Electrocatalytic regio- and stereoselective carboxylation of terminal alkynes with CO2 DOI Creative Commons
Pan Zhou,

Haoran Jiao,

Yue Jing

et al.

Green Synthesis and Catalysis, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 1, 2024

Language: Английский

Efficient Electrochemical Co‐Reduction of Carbon Dioxide and Nitrate to Urea with High Faradaic Efficiency on Cobalt‐Based Dual‐Sites DOI

Xiaoya Fan,

Chaozhen Liu,

Xun He

et al.

Advanced Materials, Journal Year: 2024, Volume and Issue: 36(25)

Published: April 2, 2024

Abstract Renewable electricity‐powered nitrate/carbon dioxide co‐reduction reaction toward urea production paves an attractive alternative to industrial processes and offers a clean on‐site approach closing the global nitrogen cycle. However, its large‐scale implantation is severely impeded by challenging C–N coupling requires electrocatalysts with high activity/selectivity. Here, cobalt‐nanoparticles anchored on carbon nanosheet (Co NPs@C) are proposed as catalyst electrode boost yield Faradaic efficiency (FE) electrosynthesis enhanced coupling. Such Co NPs@C renders superb urea‐producing activity FE reaching 54.3% of 2217.5 µg h −1 mg cat. , much superior NPs C counterparts, meanwhile shows strong stability. The affords rich catalytically active sites, fast reactant diffusion, sufficient catalytic surfaces‐electrolyte contacts favored charge ion transfer efficiencies. theoretical calculations reveal that high‐rate formation *CO *NH 2 intermediates crucial for facilitating synthesis.

Language: Английский

Citations

47
Visible-Light-Induced C–H Cyanoalkylation of Azauracils with Cycloketone Oxime Esters via Catalytic EDA Complex DOI
Xiaolong Huang,

Dong‐Liang Zhang,

Qing Li

et al.

Organic Letters, Journal Year: 2024, Volume and Issue: 26(18), P. 3727 - 3732

Published: April 28, 2024

Photoexcitation electron donor-acceptor (EDA) complexes provide an effective approach to produce radicals under mild conditions, while the catalytic version of EDA complex photoactivation remains scarce. Herein, we report a visible-light-induced organophotocatalytic pathway for cyanoalkylation azauracils using inexpensive and readily available 1,4-diazabicyclo[2.2.2]octane (DABCO) as donor. This synthetic method exhibits exceptional compatibility with various functional groups presents 34 examples in high yields. The efficient offers environmentally friendly sustainable route toward enhancing structural diversity azauracils.

Language: Английский

Citations

10
Visible-light-driven EDA complex-promoted cascade cyclization to construct 4-cyanoalkyl isoquinoline-1,3-diones DOI

Dong‐Liang Zhang,

Zhanggao Le,

Qing Li

et al.

Chemical Communications, Journal Year: 2024, Volume and Issue: 60(21), P. 2958 - 2961

Published: Jan. 1, 2024

Visible-light-driven EDA complex-promoted ring-opening of cycloketone oxime esters to synthesise various 4-cyanoalkylated isoquinoline-1,3-diones with acryloylbenzamides was developed.

Language: Английский

Citations

9
Photochemical Reductive Carboxylation of N-Benzoyl Imines with Oxalate Accelerated by Formation of EDA Complexes DOI
Wenwen Liu, Pei Xu,

Hui-Xian Jiang

et al.

ACS Catalysis, Journal Year: 2024, Volume and Issue: 14(13), P. 10053 - 10059

Published: June 20, 2024

Language: Английский

Citations

8
Photocatalytic deuterocarboxylation of alkynes with oxalate DOI Creative Commons

Pei Xu,

Hao-Qiang Jiang,

Hui Xu

et al.

Chemical Science, Journal Year: 2024, Volume and Issue: 15(32), P. 13041 - 13048

Published: Jan. 1, 2024

Herein, a catalytic photoredox-neutral strategy for alkyne deuterocarboxylation with tetrabutylammonium oxalate as the carbonyl source and D

Language: Английский

Citations

4
Visible Light-Induced C–H Alkylation of Azauracils with N-Hydroxyphthalimide Esters via Catalytic EDA Complex DOI
Zhiqiang Zhu,

Wenyi Zhang,

Xiao‐Long Huang

et al.

The Journal of Organic Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 13, 2025

Herein, we report sodium iodide (NaI)-catalyzed decarboxylative C–H alkylation of azauracils with N-hydroxyphthalimide (NHPI) esters facilitated by visible light activation catalytic electron donor–acceptor (EDA) complexes. Control experiments and density functional theory calculations suggest that the coupling reaction proceeds via a transiently assembled EDA complex between NHPI ester NaI in N,N-dimethylacetamide solvent. This synthetic method efficiently applies to primary, secondary, tertiary under mild, photocatalyst-free, redox-neutral conditions, achieving high yields desired alkylated azauracils.

Language: Английский

Citations

0
Metallaphotoredox-catalyzed alkynylcarboxylation of alkenes with CO2 and alkynes for expedient access to β-alkynyl acids DOI Creative Commons

Jincheng Xu,

Jun‐Ping Yue, Min Pan

et al.

Nature Communications, Journal Year: 2025, Volume and Issue: 16(1)

Published: Feb. 21, 2025

Carboxylation with CO2 offers an attractive and sustainable access to valuable carboxylic acids. Among these methods, direct C−H carboxylation of terminal alkynes has attracted much attention for one-carbon homologation alkynes, enabling rapid synthesis propiolic In contrast, the multi-carbons construct important non-conjugated alkynyl-containing acids not been reported. Herein, we present alkynylcarboxylation alkenes via photoredox copper dual catalysis. This protocol provides a practical method form alkynyl from readily available CO2. Additionally, this approach also features mild (room temperature, 1 atm CO2) redox-neutral conditions, high atom step economy, good functional group tolerance, selectivities. Moreover, diverse transformations β-alkynyl acid products bioactive molecule (GPR40/FFA1 agonist) further illustrate synthetic utility methodology. The report multi-carbon is rare. authors catalysis, affording

Language: Английский

Citations

0
CO2 Fixation into Useful Aromatic Carboxylic Acids via C (sp2)–X Bonds Functionalization DOI
Youwen Chen, Mingqiang Chen, Xinyu Li

et al.

Topics in Current Chemistry, Journal Year: 2025, Volume and Issue: 383(1)

Published: March 3, 2025

Language: Английский

Citations

0
Visible-Light Photocatalytic Nucleophilic Addition of 4-Pyridylphosphonium Salts to CO2 and Carbonyl Compounds DOI

Wenwen Cui,

Bin Li, Baiquan Wang

et al.

Organic Letters, Journal Year: 2025, Volume and Issue: unknown

Published: March 24, 2025

A visible-light photocatalytic nucleophilic addition of 4-pyridylphosphonium salts to CO2 and carbonyl compounds is reported. The reaction has mild conditions, good functional group tolerance, a wide range substrates. Mechanistic studies show that the may occur through pyridylphosphonium salt radical anion, pyridyl radical, anion intermediates. By combination with C4-H phosphination, this method can be applied late-stage C-H functionalization drugs containing pyridine unit.

Language: Английский

Citations

0
Photocatalytic Sequential Dimerization and Skeletal Rearrangement of Quinolines: Facile Synthesis of Indole–Methylquinoline Hybrids DOI

Long-Fei Dai,

Yuan‐Xu Jiang, Dongli Yu

et al.

ACS Catalysis, Journal Year: 2025, Volume and Issue: unknown, P. 7792 - 7799

Published: April 25, 2025

Language: Английский

Citations

0