Electron Donor-Acceptor Complex Enabled Photocascade Strategy for Synthesis of trans-Dihydrofuro[3,2-c]chromen-4-one Scaffolds via Radical Conjugate Addition of Pyridinium Ylide DOI
Sovan Dey, Arindam Das, Ram Naresh Yadav

et al.

Chemical Communications, Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 1, 2024

A photocascade strategy is disclosed for the synthesis of trans -dihydrofurocoumarin utilising EDA complex followed by 1,4-radical conjugate addition pyridinium ylide.

Language: Английский

Visible-Light-Induced C–H Cyanoalkylation of Azauracils with Cycloketone Oxime Esters via Catalytic EDA Complex DOI
Xiaolong Huang,

Dong‐Liang Zhang,

Qing Li

et al.

Organic Letters, Journal Year: 2024, Volume and Issue: 26(18), P. 3727 - 3732

Published: April 28, 2024

Photoexcitation electron donor-acceptor (EDA) complexes provide an effective approach to produce radicals under mild conditions, while the catalytic version of EDA complex photoactivation remains scarce. Herein, we report a visible-light-induced organophotocatalytic pathway for cyanoalkylation azauracils using inexpensive and readily available 1,4-diazabicyclo[2.2.2]octane (DABCO) as donor. This synthetic method exhibits exceptional compatibility with various functional groups presents 34 examples in high yields. The efficient offers environmentally friendly sustainable route toward enhancing structural diversity azauracils.

Language: Английский

Citations

11
Titanium in photocatalytic organic transformations: current applications and future developments DOI
Jia‐Lin Tu, Binbin Huang

Organic & Biomolecular Chemistry, Journal Year: 2024, Volume and Issue: 22(33), P. 6650 - 6664

Published: Jan. 1, 2024

Titanium, as an important transition metal, has garnered extensive attention in both industry and academia due to its excellent mechanical properties, corrosion resistance, unique reactivity organic synthesis. In the field of photocatalysis, titanium-based compounds such titanium dioxide (TiO

Language: Английский

Citations

6
Visible-Light-Catalyzed Fast Synthesis of 1,4-Benzoxazepine Derivatives from 2-Alkoxyarylaldehydes and N-Arylglycines DOI
Sheng Huang, Haibo Zhu, Anbang Wang

et al.

The Journal of Organic Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 3, 2025

A novel photocatalytic method for the synthesis of 1,4-benzoxazepine using 2-alkoxyarylaldehyde as an oxygen source and N-arylglycine a nitrogen has been reported. This is mild, efficient, fast, corresponding reaction can be completed within 2 h at room temperature under atmosphere light-irradiation conditions. Mechanistic studies have confirmed that this scheme involves decarboxylation cyclization provides convenient pathway preparation various 2-alkyl-N-phenyl-substituted 1,4-benzoxazepine.

Language: Английский

Citations

0
Visible Light-Induced C–H Alkylation of Azauracils with N-Hydroxyphthalimide Esters via Catalytic EDA Complex DOI
Zhiqiang Zhu,

Wenyi Zhang,

Xiao‐Long Huang

et al.

The Journal of Organic Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 13, 2025

Herein, we report sodium iodide (NaI)-catalyzed decarboxylative C–H alkylation of azauracils with N-hydroxyphthalimide (NHPI) esters facilitated by visible light activation catalytic electron donor–acceptor (EDA) complexes. Control experiments and density functional theory calculations suggest that the coupling reaction proceeds via a transiently assembled EDA complex between NHPI ester NaI in N,N-dimethylacetamide solvent. This synthetic method efficiently applies to primary, secondary, tertiary under mild, photocatalyst-free, redox-neutral conditions, achieving high yields desired alkylated azauracils.

Language: Английский

Citations

0
Organophotocatalytic Three‐Component Assembly of C4‐Cyanoalkylated Phthalazin‐1(2H)‐Ones DOI Open Access

Poornima Mishra,

Ruchir Kant,

Namrata Rastogi

et al.

Chemistry - An Asian Journal, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 14, 2025

Abstract The present work documents construction of C4‐cyanoalkylated phthalazinones under visible light‐mediated conditions. three‐component reaction involving aryl hydrazines, 2‐formylbenzoic acids and cyclobutanone oxime esters with organic dye Eosin Y as photocatalyst, features initial formation subsequent cyanoalkylation phthalazin‐1(2H)‐one in one pot. is notable for mild conditions, operational simplicity, wide substrate scope good yields the products. phthalazinone products were further converted into other valuable derivatives.

Language: Английский

Citations

0
Photocatalytic synthesis of dual acylmethylation derivates of indole[2,1-a]isoquinolinones via tandem cyclization/C3 acyl methylation DOI
Zongbo Xie, Wenli Li, Weiwei Zhang

et al.

Molecular Catalysis, Journal Year: 2025, Volume and Issue: 580, P. 115058 - 115058

Published: April 15, 2025

Language: Английский

Citations

0
Visible-Light-Induced 4CzIPN-Catalyzed Alkylamination of Alkenes via Cyclobutanone Oxime Esters and Anilines DOI
Jianghong Liu, Zeyu Tian,

Zhen-Ye Wu

et al.

The Journal of Organic Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: April 22, 2025

We disclosed an organophotoredox-catalyzed three-component oxidative radical-polar crossover strategy for constructing 1,2-alkylamination products. Cycloketone oxime derivatives were used as cyanoalkyl radical precursors and anilines the nucleophiles. This facile protocol shows a good reaction yield broad substrate scope.

Language: Английский

Citations

0
A General Electron Donor‐Acceptor Photoactivation Using Oxime Esters Enabled Divergent Thioetherifications† DOI

Maojian Lu,

Liang‐Liang Jiang,

Yueming Xu

et al.

Chinese Journal of Chemistry, Journal Year: 2024, Volume and Issue: 42(22), P. 2751 - 2756

Published: July 12, 2024

Comprehensive Summary The EDA complex‐mediated reactions involving oxime esters have been few studied. Herein, an complex formed by thiophenolate anion and ester is reported for photoinduced divergent synthesis of thioethers, depending on different types esters. Operational simplicity, mild reaction conditions, flexible options leaving group demonstrate the generality synthetic utility this approach. Such approach can also enable interesting thiol‐catalysis phenanthridines.

Language: Английский

Citations

3
Visible-Light-Induced alkyl-arylation of olefins via a Halogen-Atom Transfer Process DOI

Ren Juan,

Xiao‐Feng Xia

Organic & Biomolecular Chemistry, Journal Year: 2024, Volume and Issue: 22(31), P. 6370 - 6375

Published: Jan. 1, 2024

Visible-light-induced three-component 1,2-alkyl-arylation of alkenes and alkyl radical addition/cyclization acrylamides have been realized using a photocatalytic halogen-atom transfer (XAT) strategy.

Language: Английский

Citations

1
Electron Donor-Acceptor Complex Enabled Photocascade Strategy for Synthesis of trans-Dihydrofuro[3,2-c]chromen-4-one Scaffolds via Radical Conjugate Addition of Pyridinium Ylide DOI
Sovan Dey, Arindam Das, Ram Naresh Yadav

et al.

Chemical Communications, Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 1, 2024

A photocascade strategy is disclosed for the synthesis of trans -dihydrofurocoumarin utilising EDA complex followed by 1,4-radical conjugate addition pyridinium ylide.

Language: Английский

Citations

0