Background:
The
aim
of
this
study
is
to
explore
the
independent
and
joint
associations
between
physical
activity
(PA)
sleep
duration
with
depressive
symptoms.
Methods:
We
included
analyzed
18,052
participants
(age
≥
20
years)
from
cross-sectional
National
Health
Nutrition
Examination
Survey
(NHANES)
conducted
2007
2014.
Results:
After
adjustment,
both
males
females
showed
a
significant
correlation
PA,
duration,
In
association
analysis,
we
found:
1.
interaction
PA
was
statistically
in
but
not
(P=0.380).
2.
Compared
individuals
lowest
level
meeting
Sleep
Foundation's
(NSF)
guidelines,
those
highest
recommended
had
79%
decrease
depression
risk
(odds
ratio
[OR]
0.21,
95%
confidence
interval
[CI]
0.14-0.32)
74%
(OR
0.26,
CI
0.20-0.35).
3.
male
adhering
NSF
each
increase
quartile
associated
19%
reduction
0.81,
0.71-0.92).
Conversely,
among
there
23%
0.77,
0.69-0.86).
For
female
participants,
respective
reductions
are
20%
0.80,
0.73-0.89)
14%
0.86,
0.80-0.93).
Conclusion:
males,
adherence
weakens
relationship
depression,
while
opposite
observed
for
females.
Diabetic Medicine,
Journal Year:
2023,
Volume and Issue:
41(4)
Published: Dec. 29, 2023
Abstract
Aims
To
investigate
if
diabetic
complications
increase
the
risk
of
depression
and/or
anxiety
among
adults
with
type
2
diabetes.
Methods
This
register‐based,
prospective
study
included
265,799
adult
individuals
diagnosed
diabetes
between
1997
and
2017
without
a
recent
history
or
anxiety.
Diabetic
cardiovascular
disease,
amputation
lower
extremities,
neuropathy,
nephropathy
retinopathy.
Both
were
defined
by
hospital
contacts
prescription‐based
medication.
All
followed
from
date
diagnosis
until
incident
anxiety,
emigration,
death
31
December
2018,
whichever
occurred
first.
Results
The
total
time
was
1,915,390
person‐years.
incidence
rate
3368
per
100,000
person‐years
1929
those
without.
Having
developing
any
complication
associated
an
increased
(HR
1.77,
95%
CI
1.73–1.80).
for
all
types
complications.
strongest
association
found
extremities
2.16,
2.01–2.31)
weakest
retinopathy
1.13,
1.09–1.17).
Conclusion
Individuals
are
at
points
towards
importance
clinical
focus
on
mental
well‐being
medRxiv (Cold Spring Harbor Laboratory),
Journal Year:
2024,
Volume and Issue:
unknown
Published: Jan. 16, 2024
Abstract
Depression
and
anxiety
are
prevalent
in
people
with
a
chronic
physical
illness.
Increasing
evidence
suggests
that
co-occurring
mental
illness
is
associated
shared
biological
pathways.
However,
little
known
about
the
brain’s
role
mediating
links
between
health.
Using
multimodal
brain
imaging
organ-specific
physiological
markers
from
UK
Biobank,
we
establish
prospective
associations
baseline
health
of
seven
body
organs
outcomes
at
4-14
years
follow-up,
focussing
on
depression
anxiety.
We
reveal
multiple
pathways,
mediated
by
brain,
through
which
poor
organ
may
lead
to
identify
several
lifestyle
factors
influence
their
selective
impact
physiology
specific
systems
structure.
Our
work
reveals
interplay
collective
Pathways
elucidated
here
inform
behavioral
interventions
mitigate
or
prevent
synergistic
co-occurrence
disorders.
bioRxiv (Cold Spring Harbor Laboratory),
Journal Year:
2024,
Volume and Issue:
unknown
Published: March 27, 2024
Abstract
Despite
depression
being
a
leading
cause
of
global
disability,
neuroimaging
studies
have
struggled
to
identify
replicable
neural
correlates
or
explain
limited
variance.
This
challenge
may,
in
part,
stem
from
the
intertwined
state
(current
symptoms;
variable)
and
trait
(general
propensity;
stable)
experiences
depression.
Here,
we
sought
disentangle
by
leveraging
longitudinal
cohort
stratifying
individuals
into
four
groups:
those
remission
(‘trait
group’),
with
large
severity
changes
symptomatology
(‘state
their
respective
matched
control
groups
(total
analytic
n=1,030).
We
hypothesized
that
spatial
network
organization
would
be
linked
due
its
temporal
stability,
whereas
functional
connectivity
between
networks
more
sensitive
state-dependent
symptoms
capacity
fluctuate.
identified
15
large-scale
probabilistic
resting-state
fMRI
data
performed
group
comparisons
on
amplitude,
connectivity,
overlap
these
networks,
using
participants
as
reference.
Our
findings
revealed
higher
amplitude
visual
for
at
time
remission,
contrast
controls.
observation
may
suggest
altered
processing
predisposed
developing
over
time.
No
significant
differences
were
observed
any
other
measures
trait-control
comparison,
nor
state-control
comparison.
These
results
underscore
overlooked
contribution
psychopathology
provide
evidence
distinct
Background:
The
aim
of
this
study
is
to
explore
the
independent
and
joint
associations
between
physical
activity
(PA)
sleep
duration
with
depressive
symptoms.
Methods:
We
included
analyzed
18,052
participants
(age
≥
20
years)
from
cross-sectional
National
Health
Nutrition
Examination
Survey
(NHANES)
conducted
2007
2014.
Results:
After
adjustment,
both
males
females
showed
a
significant
correlation
PA,
duration,
In
association
analysis,
we
found:
1.
interaction
PA
was
statistically
in
but
not
(P=0.380).
2.
Compared
individuals
lowest
level
meeting
Sleep
Foundation's
(NSF)
guidelines,
those
highest
recommended
had
79%
decrease
depression
risk
(odds
ratio
[OR]
0.21,
95%
confidence
interval
[CI]
0.14-0.32)
74%
(OR
0.26,
CI
0.20-0.35).
3.
male
adhering
NSF
each
increase
quartile
associated
19%
reduction
0.81,
0.71-0.92).
Conversely,
among
there
23%
0.77,
0.69-0.86).
For
female
participants,
respective
reductions
are
20%
0.80,
0.73-0.89)
14%
0.86,
0.80-0.93).
Conclusion:
males,
adherence
weakens
relationship
depression,
while
opposite
observed
for
females.