Applied Microbiology and Biotechnology, Journal Year: 2013, Volume and Issue: 97(21), P. 9291 - 9321
Published: Sept. 21, 2013
Language: Английский
Applied Microbiology and Biotechnology, Journal Year: 2013, Volume and Issue: 97(21), P. 9291 - 9321
Published: Sept. 21, 2013
Language: Английский
Journal of Cleaner Production, Journal Year: 2019, Volume and Issue: 242, P. 118319 - 118319
Published: Sept. 14, 2019
Language: Английский
Citations
249Molecules, Journal Year: 2019, Volume and Issue: 24(22), P. 4182 - 4182
Published: Nov. 18, 2019
Seaweeds have received huge interest in recent years given their promising potentialities. Their antioxidant, anti-inflammatory, antitumor, hypolipemic, and anticoagulant effects are among the most renowned studied bioactivities so far, these been increasingly associated with content richness both primary secondary metabolites. Although metabolites a pivotal importance such as polysaccharides (fucoidans, agars, carragenans, ulvans, alginates, laminarin), data shown that some largely determines effective bioactive potential of seaweeds. Among metabolites, phenolic compounds feature prominently. The present review provides remarkable insights into seaweed research, specifically addressing its chemical composition, phytopharmacology, cosmetic applications.
Language: Английский
Citations
239Marine Drugs, Journal Year: 2015, Volume and Issue: 13(1), P. 202 - 221
Published: Jan. 7, 2015
Every year, hundreds of new compounds are discovered from the metabolites marine organisms. Finding and useful is one crucial drivers for this field research. Here we describe statistics bioactive organisms 1985 to 2012. This work based on our database, which contains information more than 15,000 chemical substances including 4196 natural products. We performed a comprehensive statistical analysis understand characteristics novel detail temporal trends, structures, species distribution, research progress. hope meta-analysis will provide into bioactivity products drug development.
Language: Английский
Citations
238Natural Product Reports, Journal Year: 2014, Volume and Issue: 31(3), P. 381 - 399
Published: Jan. 1, 2014
Actinomycetes are known for their unprecedented ability to produce novel lead compounds of clinical and pharmaceutical importance. This review focuses on the diversity, abundance methodological approaches targeting marine sponge-associated actinomycetes. Additionally, qPCR data actinomycete abundances in different sponge species other environmental sources presented. The natural products literature is covered, we here reporting chemical structures, biological activities, as well source organisms from which they were isolated.
Language: Английский
Citations
237Frontiers in Marine Science, Journal Year: 2017, Volume and Issue: 4
Published: Jan. 31, 2017
Submarine canyons are major geomorphic features of continental margins around the world. Several recent multidisciplinary projects focused on study have considerably increased our understanding their ecological role, goods and services they provide to human populations, impacts that activities overall condition. Pressures from include fishing, dumping land-based mine tailings, oil gas extraction. Moreover, hydrodynamic processes enhance down-canyon transport litter. The effects climate change may modify intensity currents. This potential hydrographic is predicted impact structure functioning canyon communities as well affect nutrient supply deep-ocean ecosystem. review not only identifies status canyons, current future issues for conservation, but also highlights need a better anthropogenic ecosystems proposes other research required inform management measures protect ecosystems.
Language: Английский
Citations
230PLoS ONE, Journal Year: 2014, Volume and Issue: 9(1), P. e85289 - e85289
Published: Jan. 22, 2014
This study aimed to evaluate the effects of twenty species tropical macroalgae on in vitro fermentation parameters, total gas production (TGP) and methane (CH4) when incubated rumen fluid from cattle fed a low quality roughage diet. Primary biochemical parameters were characterized included proximate, elemental, fatty acid (FAME) analysis. Macroalgae control, decorticated cottonseed meal (DCS), for 72 h, where was continuously monitored. Post-fermentation including CH4 production, pH, ammonia, apparent organic matter degradability (OMd), volatile (VFA) concentrations measured. All had lower TGP than DCS. Dictyota Asparagopsis strongest effects, inhibiting by 53.2% 61.8%, 92.2% 98.9% after respectively. Both also resulted lowest VFA concentration, highest molar concentration propionate among all analysed, indicating that anaerobic affected. Overall, there no strong relationships between or >70 analysed. However, zinc >0.10 g.kg−1 may potentially interact with other components influence production. The lack relationship primary biochemistry suggests significant decreases are associated secondary metabolites produced effective macroalgae. most species, Asparagopsis, offers promising alternative mitigation enteric emissions.
Language: Английский
Citations
214Marine Drugs, Journal Year: 2015, Volume and Issue: 13(5), P. 3182 - 3230
Published: May 21, 2015
Marine ecosystems cover more than 70% of the globe’s surface. These habitats are occupied by a great diversity marine organisms that produce highly structural diverse metabolites as defense mechanism. In last decades, these have been extracted and isolated in order to test them different bioassays assess their potential fight human diseases. Since traditional extraction techniques both solvent- time-consuming, this review emphasizes alternative techniques, such supercritical fluid extraction, pressurized solvent microwave-assisted ultrasound-assisted pulsed electric field-assisted enzyme-assisted with switchable solvents ionic liquids, applied search for compounds. Only studies published 21st century considered.
Language: Английский
Citations
205Environmental Toxicology and Pharmacology, Journal Year: 2016, Volume and Issue: 48, P. 22 - 30
Published: Oct. 4, 2016
Language: Английский
Citations
200Frontiers in Pharmacology, Journal Year: 2018, Volume and Issue: 9
Published: Aug. 6, 2018
Marine environment has demonstrated to be an interesting source of compounds with uncommon and unique chemical features on which the molecular modelling synthesis new drugs can based greater efficacy specificity for therapeutics. Cancer is a growing public health threat, despite advances in biomedical research technology, there urgent need development anticancer drugs. In this field, it estimated that more than 60% commercially available are natural biomimetic inspired. Among marine organisms, algae have been revealed one major sources origin, including those exhibiting antitumour cytotoxic potential by mediating specific inhibitory activities number key cellular processes, apoptosis pathways, angiogenesis, migration invasion both vitro vivo models, revealing their used as anti-cancer This review will focus bioactive molecules from potential, origin uses, special emphasis Sphaerococcus coronopifolius producer compounds.
Language: Английский
Citations
195Natural Product Reports, Journal Year: 2023, Volume and Issue: 40(2), P. 275 - 325
Published: Jan. 1, 2023
A comprehensive review of 1425 new MNPs including a novel cyanobacterial cyclodepsipeptide, gatorbulin-1, that targets 7th tubulin binding site.
Language: Английский
Citations
189