Culturable rare Actinomycetes: diversity, isolation and marine natural product discovery DOI Open Access
Ramesh Subramani,

William G.L. Aalbersberg

Applied Microbiology and Biotechnology, Journal Year: 2013, Volume and Issue: 97(21), P. 9291 - 9321

Published: Sept. 21, 2013

Language: Английский

Sustainable agriculture options for production, greenhouse gasses and pollution alleviation, and nutrient recycling in emerging and transitional nations - An overview DOI
Moyosore Joseph Adegbeye, P. Ravi Kanth Reddy,

A. I. Obaisi

et al.

Journal of Cleaner Production, Journal Year: 2019, Volume and Issue: 242, P. 118319 - 118319

Published: Sept. 14, 2019

Language: Английский

Citations

249

Current Trends on Seaweeds: Looking at Chemical Composition, Phytopharmacology, and Cosmetic Applications DOI Creative Commons
Bahare Salehi, Javad Sharifi‐Rad, Ana M. L. Seca

et al.

Molecules, Journal Year: 2019, Volume and Issue: 24(22), P. 4182 - 4182

Published: Nov. 18, 2019

Seaweeds have received huge interest in recent years given their promising potentialities. Their antioxidant, anti-inflammatory, antitumor, hypolipemic, and anticoagulant effects are among the most renowned studied bioactivities so far, these been increasingly associated with content richness both primary secondary metabolites. Although metabolites a pivotal importance such as polysaccharides (fucoidans, agars, carragenans, ulvans, alginates, laminarin), data shown that some largely determines effective bioactive potential of seaweeds. Among metabolites, phenolic compounds feature prominently. The present review provides remarkable insights into seaweed research, specifically addressing its chemical composition, phytopharmacology, cosmetic applications.

Language: Английский

Citations

239

Statistical Research on the Bioactivity of New Marine Natural Products Discovered during the 28 Years from 1985 to 2012 DOI Creative Commons
Yiwen Hu, Jiahui Chen,

Guping Hu

et al.

Marine Drugs, Journal Year: 2015, Volume and Issue: 13(1), P. 202 - 221

Published: Jan. 7, 2015

Every year, hundreds of new compounds are discovered from the metabolites marine organisms. Finding and useful is one crucial drivers for this field research. Here we describe statistics bioactive organisms 1985 to 2012. This work based on our database, which contains information more than 15,000 chemical substances including 4196 natural products. We performed a comprehensive statistical analysis understand characteristics novel detail temporal trends, structures, species distribution, research progress. hope meta-analysis will provide into bioactivity products drug development.

Language: Английский

Citations

238

Diversity, abundance and natural products of marine sponge-associated actinomycetes DOI
Usama Ramadan Abdelmohsen, Kristina Bayer, Ute Hentschel

et al.

Natural Product Reports, Journal Year: 2014, Volume and Issue: 31(3), P. 381 - 399

Published: Jan. 1, 2014

Actinomycetes are known for their unprecedented ability to produce novel lead compounds of clinical and pharmaceutical importance. This review focuses on the diversity, abundance methodological approaches targeting marine sponge-associated actinomycetes. Additionally, qPCR data actinomycete abundances in different sponge species other environmental sources presented. The natural products literature is covered, we here reporting chemical structures, biological activities, as well source organisms from which they were isolated.

Language: Английский

Citations

237

Ecological Role of Submarine Canyons and Need for Canyon Conservation: A Review DOI Creative Commons
U. Fernández-Arcaya, Eva Ramírez-Llodra, Jacopo Aguzzi

et al.

Frontiers in Marine Science, Journal Year: 2017, Volume and Issue: 4

Published: Jan. 31, 2017

Submarine canyons are major geomorphic features of continental margins around the world. Several recent multidisciplinary projects focused on study have considerably increased our understanding their ecological role, goods and services they provide to human populations, impacts that activities overall condition. Pressures from include fishing, dumping land-based mine tailings, oil gas extraction. Moreover, hydrodynamic processes enhance down-canyon transport litter. The effects climate change may modify intensity currents. This potential hydrographic is predicted impact structure functioning canyon communities as well affect nutrient supply deep-ocean ecosystem. review not only identifies status canyons, current future issues for conservation, but also highlights need a better anthropogenic ecosystems proposes other research required inform management measures protect ecosystems.

Language: Английский

Citations

230

Effects of Marine and Freshwater Macroalgae on In Vitro Total Gas and Methane Production DOI Creative Commons
Lorenna Machado, Marie Magnusson, Nicholas A. Paul

et al.

PLoS ONE, Journal Year: 2014, Volume and Issue: 9(1), P. e85289 - e85289

Published: Jan. 22, 2014

This study aimed to evaluate the effects of twenty species tropical macroalgae on in vitro fermentation parameters, total gas production (TGP) and methane (CH4) when incubated rumen fluid from cattle fed a low quality roughage diet. Primary biochemical parameters were characterized included proximate, elemental, fatty acid (FAME) analysis. Macroalgae control, decorticated cottonseed meal (DCS), for 72 h, where was continuously monitored. Post-fermentation including CH4 production, pH, ammonia, apparent organic matter degradability (OMd), volatile (VFA) concentrations measured. All had lower TGP than DCS. Dictyota Asparagopsis strongest effects, inhibiting by 53.2% 61.8%, 92.2% 98.9% after respectively. Both also resulted lowest VFA concentration, highest molar concentration propionate among all analysed, indicating that anaerobic affected. Overall, there no strong relationships between or >70 analysed. However, zinc >0.10 g.kg−1 may potentially interact with other components influence production. The lack relationship primary biochemistry suggests significant decreases are associated secondary metabolites produced effective macroalgae. most species, Asparagopsis, offers promising alternative mitigation enteric emissions.

Language: Английский

Citations

214

Alternative and Efficient Extraction Methods for Marine-Derived Compounds DOI Creative Commons
Clara Grosso, Patrı́cia Valentão, Federico Ferreres

et al.

Marine Drugs, Journal Year: 2015, Volume and Issue: 13(5), P. 3182 - 3230

Published: May 21, 2015

Marine ecosystems cover more than 70% of the globe’s surface. These habitats are occupied by a great diversity marine organisms that produce highly structural diverse metabolites as defense mechanism. In last decades, these have been extracted and isolated in order to test them different bioassays assess their potential fight human diseases. Since traditional extraction techniques both solvent- time-consuming, this review emphasizes alternative techniques, such supercritical fluid extraction, pressurized solvent microwave-assisted ultrasound-assisted pulsed electric field-assisted enzyme-assisted with switchable solvents ionic liquids, applied search for compounds. Only studies published 21st century considered.

Language: Английский

Citations

205

Potential anti-inflammatory natural products from marine algae DOI
Ilekuttige Priyan Shanura Fernando,

Jae‐Woon Nah,

You‐Jin Jeon

et al.

Environmental Toxicology and Pharmacology, Journal Year: 2016, Volume and Issue: 48, P. 22 - 30

Published: Oct. 4, 2016

Language: Английский

Citations

200

From Marine Origin to Therapeutics: The Antitumor Potential of Marine Algae-Derived Compounds DOI Creative Commons
Celso Alves, Joana Silva, Susete Pintéus

et al.

Frontiers in Pharmacology, Journal Year: 2018, Volume and Issue: 9

Published: Aug. 6, 2018

Marine environment has demonstrated to be an interesting source of compounds with uncommon and unique chemical features on which the molecular modelling synthesis new drugs can based greater efficacy specificity for therapeutics. Cancer is a growing public health threat, despite advances in biomedical research technology, there urgent need development anticancer drugs. In this field, it estimated that more than 60% commercially available are natural biomimetic inspired. Among marine organisms, algae have been revealed one major sources origin, including those exhibiting antitumour cytotoxic potential by mediating specific inhibitory activities number key cellular processes, apoptosis pathways, angiogenesis, migration invasion both vitro vivo models, revealing their used as anti-cancer This review will focus bioactive molecules from potential, origin uses, special emphasis Sphaerococcus coronopifolius producer compounds.

Language: Английский

Citations

195

Marine natural products DOI
Anthony R. Carroll, Brent R. Copp, Rohan A. Davis

et al.

Natural Product Reports, Journal Year: 2023, Volume and Issue: 40(2), P. 275 - 325

Published: Jan. 1, 2023

A comprehensive review of 1425 new MNPs including a novel cyanobacterial cyclodepsipeptide, gatorbulin-1, that targets 7th tubulin binding site.

Language: Английский

Citations

189