Analytical Chemistry,
Journal Year:
2020,
Volume and Issue:
92(14), P. 10076 - 10082
Published: June 15, 2020
Green
analytical
chemistry
focuses
on
making
procedures
more
environmentally
benign
and
safer
to
humans.
The
amounts
toxicity
of
reagents,
generated
waste,
energy
requirements,
the
number
procedural
steps,
miniaturization,
automation
are
just
a
few
multitude
criteria
considered
when
assessing
an
methodology's
greenness.
use
greenness
assessment
requires
dedicated
tools.
We
propose
Analytical
GREEnness
calculator,
comprehensive,
flexible,
straightforward
approach
that
provides
easily
interpretable
informative
result.
taken
from
12
principles
green
(SIGNIFICANCE)
transformed
into
unified
0–1
scale.
final
score
is
calculated
based
SIGNIFICANCE
principles.
result
pictogram
indicating
score,
performance
procedure
in
each
criterion,
weights
assigned
by
user.
Freely
available
software
makes
straightforward.
It
open-source
downloadable
https://mostwiedzy.pl/AGREE.
TrAC Trends in Analytical Chemistry,
Journal Year:
2021,
Volume and Issue:
138, P. 116223 - 116223
Published: Feb. 17, 2021
The
concept
of
White
Analytical
Chemistry
(WAC)
is
presented
as
an
extension
Green
(GAC).
We
propose
the
12
WAC
principles
alternative
to
known
GAC
principles.
In
addition
green
aspects,
takes
into
account
other
key
criteria
affecting
quality
method,
analytical
(red)
and
practical
(blue).
reference
RGB
color
model,
according
which
mixing
red,
blue
light
beams
gives
impression
whiteness,
a
white
method
shows
coherence
synergy
analytical,
ecological
attributes.
Whiteness
can
also
be
quantified,
based
on
assessment
individual
principles,
convenient
parameter
useful
in
comparisons
selecting
optimal
method.
closer
idea
sustainable
development
due
more
holistic
view,
it
strives
for
compromise
that
avoids
unconditional
increase
greenness
at
expense
functionality.
Green Chemistry,
Journal Year:
2021,
Volume and Issue:
23(21), P. 8657 - 8665
Published: Jan. 1, 2021
It
is
not
easy
to
find
appropriate
tools
for
the
evaluation
of
“green”
nature
analytical
methodologies
which
involve
use
compounds,
materials,
or
chemicals
manufactured
prior
step.
TrAC Trends in Analytical Chemistry,
Journal Year:
2022,
Volume and Issue:
148, P. 116530 - 116530
Published: Jan. 13, 2022
The
ten
principles
of
GSP
are
presented
with
the
aim
establishing
a
road
map
toward
development
overall
greener
analytical
methodologies.
Paramount
aspects
for
greening
sample
preparation
and
their
interconnections
identified
discussed.
These
include
use
safe
solvents/reagents
materials
that
renewable,
recycled
reusable,
minimizing
waste
generation
energy
demand,
enabling
high
throughput,
miniaturization,
procedure
simplification/automation,
operator's
safety.
Further,
importance
applying
green
metrics
assessing
greenness
methods
is
highlighted,
next
to
contribution
in
achieving
broader
goal
sustainability.
Green
preparation.
It
not
new
subdiscipline
but
guiding
principle
promotes
sustainable
through
adoption
environmentally
benign
procedures.
Analytical Chemistry,
Journal Year:
2019,
Volume and Issue:
91(16), P. 10343 - 10352
Published: July 15, 2019
Evaluation
of
an
analytical
method
is
a
fundamental
problem
in
chemistry,
and
it
never
straightforward.
In
this
article,
we
show
perspective
for
facing
issue
using
original
tool.
We
propose
model
that
allows
one
to
evaluate
any
method/procedure
global
manner.
It
refers
the
RGB
additive
color
uses
three
primary
colors
represent
main
attributes
evaluated
method:
performance
–
Red,
compliance
with
"green"
chemistry
principles
Green,
productivity/practical
effectiveness
Blue.
A
final
results
from
synthesis
colors.
To
simplify
classifications,
set
nine
(white,
magenta,
cyan,
yellow,
red,
green,
blue,
colorless/gray,
black).
The
provides
also
quantitative
parameter,
named
"method
brilliance",
which
integrates
all
treats
them
varying
importance,
adjusted
evaluation
context
subjective
user
preferences.
performed
standard
Excel
worksheets
interpretable
"at-a-glance"
adjustable
particular
specifications.
discuss
opportunities
offered
by
model,
potential
obstacles,
related
countermeasures,
as
well
future
perspectives
its
utilization.
paper
shows
examples
real
methods.
believe
can
be
applied
not
only
science
but
other
chemical
subdisciplines.
Analytical Methods,
Journal Year:
2020,
Volume and Issue:
13(3), P. 369 - 380
Published: Dec. 16, 2020
Several
assessment
tools
were
recently
introduced
for
the
evaluation
of
greenness
analytical
methods.
Each
tool
has
advantages,
disadvantages,
and
a
unique
protocol.
The
final
results
obtained
from
each
may
lead
to
dissimilar
conclusion
about
selection
greenest
method,
which
makes
decision
confusing
as
an
relies
on.
Accordingly,
in
this
comparative
case
study,
four
tools-National
Environmental
Methods
Index
(NEMI),
Eco-Scale
Assessment
(ESA),
Green
Analytical
Procedure
(GAPI),
GREEnness
metric
(AGREE)-were
tested
evaluate
16
chromatographic
methods
described
literature
commonly
used
antispasmodic
drug
Hyoscine
N-butyl
bromide
(HNBB).
importance
applying
more
than
one
when
evaluating
is
explained
study.
Despite
NEMI
simplicity,
it
was
least
effective
providing
information
method
14
out
had
same
pictogram.
ESA
AGREE
provided
reliable
numerical
assessments
that
differed
their
total
scores
whereas
100
1
each,
respectively.
merits
over
with
respect
automation
highlighting
weakest
points
techniques
need
further
improvements
terms
greenness.
GAPI
provide
fully
descriptive
three-colored
pictograms.
main
disadvantage
complexity
compared
ESA.
simplicity
GAPI.
Based
on
results,
recommendations
are
made
ESA,
GAPI,
tools,
precise
method.
Planning
should
be
assured
before
practical
trials
laboratory
reduction
chemical
hazards
released
into
environment.
Moreover,
inclusion
validation
protocols
strongly
recommended.
