BODIPY as a Multifunctional Theranostic Reagent in Biomedicine: Self‐Assembly, Properties, and Applications

Advanced Materials, Journal Year: 2022, Volume and Issue: 35(18)

Published: Nov. 18, 2022

Abstract The use of boron dipyrromethene (BODIPY) in biomedicine is reviewed. To open, its synthesis and regulatory strategies are summarized, inspiring cutting‐edge work post‐functionalization highlighted. A brief overview assembly model BODIPY then provided: introduced as a promising building block for the formation single‐ multicomponent self‐assembled systems, including nanostructures suitable aqueous environments, thereby showing great development potential supramolecular applications. frontier progress biomedical application thereafter described, supported by examples frontiers applications BODIPY‐containing smart materials: it mainly involves materials based on blocks their assemblies fluorescence bioimaging, photoacoustic imaging, disease treatment photodynamic therapy, photothermal immunotherapy. Lastly, not only current status family field but also challenges worth considering summarized. At same time, insights into future prospects biomedically applicable provided.

Language: Английский

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Advances in applied supramolecular technologies

Chemical Society Reviews, Journal Year: 2021, Volume and Issue: 50(4), P. 2737 - 2763

Published: Jan. 1, 2021

Supramolecular chemistry is a comparatively young field that to date has mainly been focused on building foundation of fundamental understanding. With much progress in this area, researchers are seeking apply knowledge the development commercially viable products. In review we seek outline historical and recent developments within supramolecular have made transition from laboratory market, bring light those technologies believe commercial potential. doing so hope may illuminate pathways market for research currently being conducted.

Language: Английский

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Nanoengineered Peptide‐Based Antimicrobial Conductive Supramolecular Biomaterial for Cardiac Tissue Engineering

Advanced Materials, Journal Year: 2021, Volume and Issue: 33(26)

Published: May 25, 2021

Abstract Owing to their dynamic nature and ordered architecture, supramolecular materials strikingly resemble organic components of living systems. Although short‐peptide self‐assembled nanostructured hydrogels are regarded as intriguing for biotechnology, application is often limited due low stability considerable challenge combining other desirable properties. Herein, a di‐Fmoc‐based hydrogelator containing the cell‐adhesive Arg–Gly–Asp (RGD) fragment that forms mechanically stable, self‐healing hydrogel designed. Molecular dynamics simulation reveals presence RGD segments on surface fibers, highlighting cell adherence capacity. Aiming impart conductivity, 3D network further nanoengineered by incorporating polyaniline (PAni). The composite demonstrate semiconductivity, excellent antibacterial activity, DNA binding Cardiac cells grown form functional synchronized monolayers. Taken together, combination these attributes in single suggests it an exceptional candidate biomaterial designed electrogenic tissue engineering.

Language: Английский

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Highly Efficient and Direct Ultralong All‐Phosphorescence from Metal–Organic Framework Photonic Glasses

Angewandte Chemie International Edition, Journal Year: 2022, Volume and Issue: 61(39)

Published: July 12, 2022

Realizing efficient and ultralong room-temperature phosphorescence (RTP) is highly desirable but remains a challenge due to the inherent competition between excited state lifetime photoluminescence quantum yield (PLQY). Herein, we report bottom-up self-assembly of transparent metal-organic framework (MOF) bulk glasses exhibiting direct all-phosphorescence (lifetime: 630.15 ms) with PLQY up 75 % at ambient conditions. These macroscopic MOF have high Young's modulus hardness, which provide rigid environment reduce non-radiative transitions boost triplet excitons. Spectral technologies theoretical calculations demonstrate directly derived from different states, indicating great capability for color-tunable afterglow emission. We further developed information storage light-emitting devices based on pure RTP fabricated photonic glasses.

Language: Английский

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Recent advances in fluorescent and colorimetric chemosensors for the detection of chemical warfare agents: a legacy of the 21st century

Chemical Society Reviews, Journal Year: 2022, Volume and Issue: 52(2), P. 663 - 704

Published: Dec. 22, 2022

This review highlights recently reported optical molecular sensors for the sensing of Chemical Warfare Agents (CWAs) including nerve agents, blister blood and other toxicants.

Language: Английский

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