Applied Biochemistry and Biotechnology, Journal Year: 2024, Volume and Issue: unknown
Published: Aug. 13, 2024
Language: Английский
Ageing Research Reviews, Journal Year: 2023, Volume and Issue: 87, P. 101927 - 101927
Published: April 7, 2023
Language: Английский
Citations
57
Sensing and Bio-Sensing Research, Journal Year: 2021, Volume and Issue: 34, P. 100463 - 100463
Published: Oct. 25, 2021
Environmental detection, monitoring and controlling of pathogenic or harmful gases has become an utmost priority. They contribute to major public health problems such as respiratory diseases, cardiovascular dysfunction central nervous system (CNS) anomalies other diseases (cancer, bronchiolitis, asthma etc.). Also, they are associated with frightening global warming thus affecting the ambient environment. Therefore, there is urgent need control mitigate these gases. Notably, existing conventional gas sensors painstakingly very slow, labour capital intensive, invasive require specialized apparatuses human operate. A glowing develop cheap, fast, efficient, highly sensitive, portable less power usage a high degree reliability been on rise. Carbon nanotubes (CNTs) have extensively explored biosensors owing fact that tubular-nanosized materials excellent biocompatibility coupled large surface area, thermal, electrical, mechanical optical properties. In recent past, invention fabrication CNTs-based their mechanisms subject intense research studies in detection this short review, we present in-depth overview survey for sensing sourced from published papers online articles. The paper also highlights challenges sensors, possible remedial actions future work opportunities area.
Language: Английский
Citations
65
Biomass Conversion and Biorefinery, Journal Year: 2022, Volume and Issue: 14(8), P. 9361 - 9383
Published: July 12, 2022
Abstract The synthesized biochars derived from sawdust (SD) SD ozone (SDO) biochar, purified (PSD) and sonicated (SSD) which was employed in the confiscation of methylene blue (MB) dye ion, were characterized employing “Brunauer–Emmett–Teller (BET), scanning electron microscope (SEM), Fourier Transform Infrared (FTIR), Thermal gravimetrical analysis (TGA).” impact various factors, such as pH, biochar dosage, initial concentration, on MB sequestration, tested this study. It found that biosorption to dependent solution with optimum observed at pH 12 for all biochars. Pseudo-second-order (PSO), Freundlich (FRH)- (SDO SSD biochars), Langmuir (LNR)- (PSD biochar) models used best describe process Based LNR model fitting experimental data, sorption capacities obtained using SDO, SSD, PSD 200, 526, 769 mg/g, respectively. Electrostatic interaction hydrogen bonding played an important role mechanism between dye. Hence, these studied PSD, prepared cheap, easily accessible, biodegradable, non-hazardous agro-waste materials can be effectively removal, treatment, management well other industrial effluents before their disposal into environment.
Language: Английский
Citations
56
Biosensors, Journal Year: 2022, Volume and Issue: 12(6), P. 365 - 365
Published: May 26, 2022
Salmonellosis is a major cause of foodborne infections, caused by Salmonella, posing health risk. It possesses the ability to infiltrate food supply chain at any point throughout manufacturing, distribution, processing or quality control process. Salmonella infection has increased severely and requires effective efficient methods for early monitoring detection. Traditional methods, such as real-time polymerase reaction culture plate, consume lot time are labor-intensive. Therefore, new quick detection on-field applications urgently needed. Biosensors provide consumer-friendly approaches diagnoses. In last few years, there been surge in research into creation reliable advanced electrochemical sensors strains samples. Electrochemical extensive accuracy reproducible results. Herein, we present comprehensive overview focusing on various mechanisms transducer. Further, explain new-generation biosensors (microfluidics, CRISPR- IOT-based) point-of care applications. This review also highlights limitations developing future possibilities.
Language: Английский
Citations
54
Food Chemistry, Journal Year: 2022, Volume and Issue: 390, P. 133219 - 133219
Published: May 14, 2022
Language: Английский
Citations
53
Biomass Conversion and Biorefinery, Journal Year: 2022, Volume and Issue: 14(2), P. 1975 - 1991
Published: Jan. 17, 2022
Language: Английский
Citations
47
Adsorption Science & Technology, Journal Year: 2022, Volume and Issue: 2022
Published: Jan. 1, 2022
Carbon nanomaterials are endowed with novel and magnificent optical, electrical, chemical, mechanical, thermal properties, a promising prospect in different advanced applications such as electronics, batteries, capacitors, wastewater treatment, membranes, heterogeneous catalysis, medical sciences. However, macroscopic synthesis of carbon materials for industrial use has been great challenge. Furthermore, structural nonhomogeneity indefinite fabrication have hindered vigorous consistent implementation these extensive technologies. Nevertheless, they offer exotic physics, result, continued to attract interest from the scientific community an effort aimed optimize their properties through innovative techniques, ensuring production discovering new applications. Hence, this study endeavours provide conscious review via comprehensive discussion various allotropes (fullerenes, nanotubes, graphene), techniques (arc discharge, laser ablation, chemical vapor deposition), energy-related fields (batteries, photocells, hydrogen storage, sensors, etc.) impending prospects.
Language: Английский
Citations
46
Trends in biotechnology, Journal Year: 2023, Volume and Issue: 41(10), P. 1248 - 1267
Published: May 4, 2023
Prostate cancer (PC) is one of the most life-threatening diseases in men and causes numerous deaths worldwide. Early on-time detection PC could dramatically improve survival.Biomarkers are useful for monitoring due to their ease sampling abundancy. Biomarkers can also be used designing reliable platforms.Various types biosensors have provided simple, sensitive, specific, cost-effective biomarkers patients' biological fluids, such as serum urine.Recent advances application biosensing platforms pave way toward clinical practice. common tumors a leading cause mortality among men, resulting ~375 000 annually Various analytical methods been designed quantitative rapid biomarkers. Electrochemical (EC), optical, magnetic developed detect tumor point-of-care (POC) settings. Although POC shown potential biomarkers, some limitations, sample preparation, should considered. To tackle shortcomings, new technologies utilized development more practical biosensors. Here, immunosensors, aptasensors, genosensors, paper-based devices, microfluidic systems, multiplex high-throughput platforms, discussed. Despite developments diagnosis treatment, remains death [1.Siegel R.L. et al.Cancer statistics, 2022.CA Cancer J. Clin. 2022; 72: 7-33Crossref PubMed Scopus (4937) Google Scholar,2.Yigci D. al.3D bioprinted glioma models.Prog. Biomed. Eng. 4042001Crossref (5) Scholar]. Worldwide, fifth was responsible 375 2020 [3.Sung H. al.Global Statistics 2020: GLOBOCAN estimates incidence worldwide 36 cancers 185 countries.CA 2021; 71: 209-249Crossref (37388) Due inconvenience physical examination lack specific symptoms, often diagnosed its advanced stages. Diagnosis initial stages plays an undeniable role increasing survival rate achieving timely treatment. diagnostic approaches proposed determination urine physical/digital rectal examination, prostate tissue biopsy imaging (e.g., resonance transrectal ultrasound) [4.Soares S.C.M. al.Digital associated factors early cancer: cross-sectional population-based study.BMC Public Health. 2019; 19: 1573Crossref Scholar, 5.Jang al.Transrectal ultrasound photoacoustic probe cancer.Sensors (Basel). 21: 1217Crossref (6) 6.Hicks R.M. al.Diagnostic accuracy (68)Ga-PSMA-11 PET/MRI compared with multiparametric MRI cancer.Radiology. 2018; 289: 730-737Crossref (102) minimize trauma pain during prevent side effects anesthesia, (see Glossary) present solution. The main purpose investigations field diagnostics identify high specificity sensitivity minimal false-positive/negative results. accurate appropriate biomarker indicate presence or severity disease enable physicians determine effective treatment management strategy. we review developing diagnostics. In contrast other recently published articles, this Review discusses various paper-based, multiplexed, microfluidic, integrated biosensors) consideration receptors transducers. Among protein PC, prostate-specific antigen (PSA) kallikrein-like seine protease glycoprotein that encoded by KLK3, approved FDA 1986 1994 prognostic nonsymptomatic patients [7.Rittenhouse H.G. al.Human kallikrein 2 (hK2) (PSA): two closely related, but distinct, kallikreins prostate.Crit. Rev. Lab. Sci. 1998; 35: 275-368Crossref (285) Scholar,8.Van Poppel al.Serum PSA-based Europe globally: past, future.Nat. Urol. 562-572Crossref (24) concentration PSA nonspecifically increases not only benign prostatic hyperplasia (BPH) prostatitis [9.Yan Y. al.On road prognosis: current status future advances.Int. Mol. 22: 13537Crossref (4) However, threshold 3–10 ng/ml determined sufficient surveillance. Cases concentrations between 3 10 considered grey zone referred further tests [10.Falagario U.G. al.Prostate biomarkers: based on different scenarios.Crit. : 1-12Google has aided there still limitations insufficient positive predictive value (PPV) noticeable false-negative results [11.Wolf A.M. al.American Society guideline update 2010.CA 2010; 60: 70-98Crossref (741) address commercial 4Kscore, Proclarix, serum-based health index (PHI), ProMark were measure several instead alone [12.Klocker al.Development validation novel multivariate risk score guide decision clinically significant cancer.BJUI Compass. 2020; 1: 15-20Crossref Scholar,13.Parekh D.J. al.A multi-institutional prospective trial USA confirms 4Kscore accurately identifies high-grade cancer.Eur. 2015; 68: 464-470Abstract Full Text PDF Multiple isoforms reported PSA. Free (fPSA), enzymatically inactive ~33-kDa fraction PSA, applied combination [14.Jansen F.H. al.Prostate-specific isoform p2PSA total free improves detection.Eur. 57: 921-927Abstract (212) Another named p2PSA, detection. PHI assay measures fPSA, through formula conditions. Human glandular kallikrein-2 structurally similar major KLK3 important [15.Schedlich L.J. al.Primary structure human gene.DNA. 1987; 6: 429-437Crossref Compared BPH, hK2 elevated [16.Becker C. al.Discrimination from those measurements serum.J. 2000; 163: 311-316Crossref Additionally, recognized predictor gray [17.Kwiatkowski M.K. al.In prostatism ratio discrimination within "gray zone" 4 ng/ml.Urology. 52: 360-365Abstract (115) 50–100-fold less than since 10–50% [18.van Gils M.P.M.Q. al.Innovations markers European research P-Mark project.Eur. 2005; 48: 1031-1041Abstract (0) Remarkably, h2K 4KscoreVR test (OPKO Health, Miami, FL, USA) using four (tPSA, h2K) purposes suspected [13.Parekh Scholar,19.Vickers A.J. panel reduce unnecessary data Randomized Study Screening Goteborg, Sweden.BMC Med. 2008; 19Crossref (194) Box 1 discuss emerging PC.Box 1Emerging PCUnderstanding neuroendocrine differentiation led PC. Admittedly, involvement cells growth widely recognized. These detected via immunohistochemical techniques applying antibodies against produced either malignant [128.Hu C.D. al.Neuroendocrine mechanism radioresistance failure.Front. Oncol. 5: 90Crossref (104) Scholar,129.Abrahamsson P.A. Neuroendocrine carcinoma.Prostate. 1999; 39: 135-148Crossref (291) Most aforementioned chromogranin (Cg)A CgB, chorionic gonadotropin, neuron-specific enolase (NSE), somatostatin members calcitonin gene family secreted into peripheral blood immunoassays [130.Parimi V. review.Am. Exp. 2014; 2: 273-285PubMed NSE CgA characteristics both [131.Kamiya N. al.Pretreatment level neuron (NSE) factor metastatic treated endocrine therapy.Eur. 2003; 44 (discussion 314): 309-314Abstract (68) Scholar,132.Ranno S. al.The chromogranin-A (CgA) cancer.Arch. Gerontol. Geriatr. 2006; 43: 117-126Crossref (28) Scholar].Considering association obesity overweight impact adipose tissue-derived hormones (adipokines), specifically omentin leptin, well VEGF hepatocyte (HGF) studied showed dramatic increase HGF, VEGF, omentin, leptin BPH. evaluation scheme [133.Fryczkowski M. al.Circulating levels HGF relevance marker cancer.Dis. Markers. 20183852401Crossref (23) Moreover, another study, pigment epithelium-derived (PEDF) investigated find whether these distinguish revealed VEGF/PEDF differentiate BPH suggesting it personalized prognosis [134.Rivera-Perez al.Evaluation PEDF preliminary study biopsies.Oncol. Lett. 15: 1072-1078PubMed Understanding Considering advantages over invasive sampling, which may result injury/trauma patients. Generally, urinary categorized proteins, DNA-based, RNA-based, exosomes, molecules. samples first 1980s. Later, studies after prostatectomy, might recurrence [20.Iwakiri al.An analysis before radical prostatectomy: evidence secretion periurethral glands.J. 1993; 149: 783-786Crossref Telomerase reverse transcriptase (TERT), crucial protecting telomeric ends chromosomes. Its hyperactivity observed majority PCs having active telomerase replicative senescence [21.Botchkina G.I. al.Noninvasive activity.Clin. Res. 11: 3243-3249Crossref Annexin A3, member calcium phospholipid binding family, cell migration metastasis With inverse correlation cancer, annexin A3 found Hence, provide develop noninvasive [22.Schostak al.Annexin urine: highly detection.J. 2009; 181: 343-353Crossref (80) Scholar,23.Gerke al.Annexins: linking Ca2+ signalling membrane dynamics.Nat. Cell Biol. 449-461Crossref (1163) matrix metalloproteinases (MMPs) invasiveness, growth, solid tumors, particularly demonstrated MMPs healthy people [24.Egeblad Werb Z. New functions progression.Nat. Cancer. 2002; 161-174Crossref MMP-9 act independent 82% [25.Roy R. al.Tumor-specific metalloproteinase fingerprinting: identification molecular weight species.Clin. 14: 6610-6617Crossref (138) simultaneous MMP vascular endothelial (VEGF) predict 1-year progression-free radiotherapy-treated Urinary higher controls [26.Miyake al.Urinary progression.Anticancer 25: 3645-3649PubMed Scholar,27.Chan L.W. radiation therapy: longitudinal kinetics throughout progression therapy.J. 2004; 499-506Crossref Sarcosine, byproduct glycine, control group [28.Sreekumar A. al.Metabolomic profiles delineate sarcosine progression.Nature. 457: 910-914Crossref (1791) Since undetectable trace amounts informative [29.Cernei al.Sarcosine biomarker--a review.Int. 2013; 13893-13908Crossref (PCA3), mRNA significantly overexpressed tissues [30.Hessels al.DD3(PCA3)-based 15-16): 8-15Abstract (588) PSA/PCA3 promising PCA3 performance [31.Bradley L.A. al.Comparative effectiveness review: testing cancer.J. 190: 389-398Crossref (70) Scholar,32.Roobol M.J. Contemporary cancer.Curr. Opin. 2011; 225-229Crossref (26) Biosensing devices conventional methods, tools enhanced biomolecules drugs body fluids blood, cerebrospinal fluid, urine, saliva, tears [33.Aliakbarinodehi al.Performance carbon nano-scale allotropes detecting midazolam paracetamol undiluted serum.IEEE Sensors 18: 5073-5081Crossref (12) Scholar,34.Shafaei al.Electrodeposition cerium oxide nanoparticles graphenized ceramic electrode (GCCE) sensitive isoprenaline differential pulse voltammetry (DPV).Anal. 55: 2418-2435Crossref (3) Enhanced EC, plasmonic Metal gold, silver, platinum, particles lower limit (LOD). outstanding physicochemical properties stability, large surface area, conductivity, carbon-based nanomaterials including graphene oxide, nanotubes, polymers, [35.Akbari Nakhjavani al.Gold silver bio/nano-hybrids-based electrochemical immunosensor ultrasensitive carcinoembryonic antigen.Biosens. Bioelectron. 141111439Crossref (53) 36.Sarabi M.R. printing microneedle arrays: challenges towards translation.J. 3D Print. 65-70Crossref 37.Rezapour Sarabi al.machine learning-enabled prediction 3D-printed features.Biosensors. 12: 491Crossref (1) Recently, (EC biosensors), extensively [38.George Kerry comprehensive applications nano-biosensor-based non-communicable communicable detection.Biomater. 9: 3576-3602Crossref While digital testing, indispensable desired. biosensor, antibodies, aptamers, cells, DNA serve biorecognition elements [39.Thevenot D.R. al.Electrochemical biosensors: recommended definitions classification.Biosens. 2001; 16: 121-131Crossref Scholar,40.Akbari CA15-3 patient plasma biosensor labeled beads.Biosens. 122: 8-15Crossref (52) transducer system chemical, thermal, piezoelectric, magnetic, mass-sensitive. Depending nature sensing platform (Figure 1), discussed three categories: immunoassays, aptamer-based probes, gene-based ligands. Furthermore, multiplexed Table summarizes Review.Table 1Biosensing biomarkersaAbbreviations: Ag@MCM, hybridized mesoporous silica nanoparticles; Anti-KLK3, Kallikrein related peptidase 3; Apt, aptamer; AuNC-Cys, gold nanocluster cysteine; AuNF, nanoflower; AuNRs, nanorods; Au-Spa, Au linked Staphylococcal A; C60, fullerene; CD14, cluster 14; CV, cyclic voltammetry; Cys, cysteamine; DETA, diethylenetriamine; DpAu, deposited gold; EN2: engrailed-2; Fc, ferrocene; FITC, fluorescein isothiocyanate; f-PSA, PSA; FTO, fluorine-doped tin oxide; GE, electrode; GOD, glucose oxidase; GOLM-1, Golgi 1; GS, sheets; HRP, horseradish peroxidase; IGF-1, insulin factor-1; IGFBP-3, insulin-like IL, ionic liquid; IL-6, interleukin-6; ITO, indium LF, label-free; N/A, available; PAA-GMNP, poly acrylic acid (PAA) modified PABA, para amino benzoic acid; PANI, polyaniline; PdNP, palladium PF-4, platelet factor-4; PICA/FGNs, poly(indole-6-carboxylic acid)/flower-like PMMA, poly(methyl methacrylate); rGO, reduced RuBPY, Tris(bipyridine)ruthenium(II) chloride; SA, streptavidin; SiNP, SiO2@Ag@SiO2 NPs, silica-coated assembled SiO2@Au-Ag Au-Ag NP alloy NPs;ssDNA, single stranded DNA; SWCNT, walled nanotube; SWV, square wave TA, tannic TSPs, tetrahedron structural probes.BiomarkerModification/ strategyLODLDRDetection methodRefsEC immunosensorsPSAMWCNT, IL/ sandwich20 pg/ml0.2–1.0 1–40 ng/mlDPV[43.Salimi al.Highly immunosensing liquid-carbon nanotubes electrode: biopsies.Biosens. 42: 439-446Crossref (128) Scholar]PSACys/Fc-PAMAMs/ LF0.001 ng/ml0.01 ng–100 ng/mlDPV[44.Cevik E. al.Construction ferrocene-PAMAM dendrimers.Biosens. 2016; 86: 1074-1079Crossref (61) Scholar]PSAGO, chit/ sandwich10 fg/ml5 pg/ml0.1 pg/ml 90 Up 35 ng/mlDPV,EIS[45.Kavosi B. al.Ultrasensitive nanoparticles/PAMAM dendrimer loaded enzyme aptamer triple signal amplification strategy.Biosens. 74: 915-923Crossref (195) Scholar]PSMAPMMA sheets/ LF9.5 ng/ml10–200 ng/mlEIS[46.Rezaei al.Design fabrication electrochemical-based nanofibrous biomarker, PSMA.Polym. Adv. Technol. 33: 1967-1977Crossref Scholar]PSAMWCNTs-IL-Chit-AuNPs–PAMAM/ sandwich1 pg/ml0.05-80 ng/mlDPV[47.Kavosi MWCNTS/chitosan/ionic liquid nanocomposite.Biosens. 20-28Crossref Scholar]PSAPdNP-PANI-C60/ sandwich1.95×10−5 ng/ml1.6×10−4 38 ng/mlCV[48.Suresh L. al.Fabrication polyaniline, fullerene-C60 nanocomposite: tool cancer.Electroanalysis. 32: 1439-1448Crossref (14) Scholar]PSAGS, Ag@MCM48/ Sandwich2 pg/ml0.01–10.0 ng/mlN/A[49.Li Y.Y. al.Label silica.Anal. Biochem. 469: 76-82Crossref (42) Scholar]PSASAM@electrode/LF100 ag/ml100 ag/ml up mg/mlEIS[50.Pihikova al.Aberrant sialylation antigen: label-free glycoprofiling samples.Anal. Chim. Acta. 934: 72-79Crossref (50) Scholar]PSMACys-AuNPs/ LF0.47 ng/ml0–5 ng/mlDPV[51.Kabay G. al.Disposable detection.Sensors Actuators B Chem. 360131667Crossref Scholar]ECL immunosensorsPSAAu-rGO, accelerator/ sandwich0.038 pg/ml0.0001 ng-mlECL[53.Fang Q. electrochemiluminescence CdWS nanocrystals Ag+@ UIO-66-NH2 coreaction acc
Language: Английский
Citations
26
Discover Nano, Journal Year: 2024, Volume and Issue: 19(1)
Published: May 2, 2024
Graphene quantum dots (GQDs) are a newly developed class of material, known as zero-dimensional nanomaterials, with characteristics derived from both carbon (CDs) and graphene. GQDs exhibit several ideal properties, including the potential to absorb incident energy, high water solubility, tunable photoluminescence, good stability, drug-loading capacity, notable biocompatibility, which make them powerful tools for various applications in field biomedicine. Additionally, can be incorporated additional materials develop nanocomposites exceptional qualities enriched functionalities. Inspired by intriguing scientific discoveries substantial contributions biomedicine, we present broad overview recent advancements GQDs-based biomedical applications. The review first outlines latest synthesis classification nanocomposite enables their use advanced composite Furthermore, systematic study drug delivery, biosensing, photothermal, photodynamic combination therapies emphasized. Finally, possibilities, challenges, paths highlighted encourage research, will lead new therapeutics global healthcare improvements.
Language: Английский
Citations
12
Environmental Science Processes & Impacts, Journal Year: 2021, Volume and Issue: 23(8), P. 1060 - 1078
Published: Jan. 1, 2021
This perspective article reports the possible relationships between climate change and SARS-CoV-2/COVID-19 pandemic vice versa .
Language: Английский
Citations
45