Laser‐Based Selective Material Processing for Next‐Generation Additive Manufacturing DOI Open Access

Huijae Park,

Jung Jae Park,

Phuong‐Danh Bui

et al.

Advanced Materials, Journal Year: 2023, Volume and Issue: 36(34)

Published: Sept. 23, 2023

The connection between laser-based material processing and additive manufacturing is quite deeply rooted. In fact, the spark that started field of idea two intersecting laser beams can selectively solidify a vat resin. Ever since, has been accompanying manufacturing, with its repertoire expanded from only photopolymer resin to virtually any material, allowing liberating customizability. As result, expected take an even more prominent role in global supply chain years come. Herein, overview selective presented various aspects: physics laser-material interactions, materials currently used processes, system configurations enable functional applications next-generation manufacturing. Additionally, current challenges prospects are discussed.

Language: Английский

Stimuli-responsive engineered living materials DOI
Laura K. Rivera‐Tarazona, Zachary T. Campbell, Taylor H. Ware

et al.

Soft Matter, Journal Year: 2020, Volume and Issue: 17(4), P. 785 - 809

Published: Dec. 23, 2020

Stimuli-responsive materials are able to undergo controllable changes in properties response external cues. Increasing efforts have been directed towards building that mimic the responsive nature of biological systems. Nevertheless, limitations remain surrounding way these synthetic interact and respond their environment. In particular, it is difficult synthesize with specificity poorly differentiated (bio)chemical weak physical stimuli. The emerging area engineered living (ELMs) includes composites combine cells materials. ELMs yielded promising advances creation stimuli-responsive diverse outputs a broad array biochemical This review describes made genetic engineering component processing-property relationships ELMs. Finally, implementation as environmental sensors, biomedical drug delivery vehicles, soft robots discussed.

Language: Английский

Citations

95
Biohybrid robots: recent progress, challenges, and perspectives DOI Creative Commons
Victoria A. Webster‐Wood, Maria Guix, Nicole Xu

et al.

Bioinspiration & Biomimetics, Journal Year: 2022, Volume and Issue: 18(1), P. 015001 - 015001

Published: Oct. 20, 2022

The past ten years have seen the rapid expansion of field biohybrid robotics. By combining engineered, synthetic components with living biological materials, new robotics solutions been developed that harness adaptability muscles, sensitivity sensory cells, and even computational abilities neurons. Biohybrid has taken popular scientific media by storm advances in field, moving out science fiction into real engineering. So how did we get here, where should go next? In this perspective, first provide historical context crucial subareas reviewing 10+ microorganism-bots sperm-bots, cyborgs, tissue-based robots. We then present critical challenges facing our perspectives on vital future steps toward creating autonomous machines.

Language: Английский

Citations

69
The emerging technology of biohybrid micro-robots: a review DOI Creative Commons
Zening Lin, Tao Jiang, Jianzhong Shang

et al.

Bio-Design and Manufacturing, Journal Year: 2021, Volume and Issue: 5(1), P. 107 - 132

Published: May 16, 2021

Abstract In the past few decades, robotics research has witnessed an increasingly high interest in miniaturized, intelligent, and integrated robots. The imperative component of a robot is actuator that determines its performance. Although traditional rigid drives such as motors gas engines have shown great prevalence most macroscale circumstances, reduction these to millimeter or even lower scale results significant increase manufacturing difficulty accompanied by remarkable performance decline. Biohybrid robots driven living cells can be potential solution overcome drawbacks benefiting from intrinsic microscale self-assembly tissues energy efficiency, which, among other unprecedented properties, also feature flexibility, self-repair, multiple degrees freedom. This paper systematically reviews development biohybrid First, biological flexible drivers introduced while emphasizing on their advantages over drivers. Second, up-to-date works regarding are reviewed detail three aspects: driving sources, materials, structures with associated control methodologies. Finally, future applications major challenges explored. Graphic abstract

Language: Английский

Citations

67
Highly robust and soft biohybrid mechanoluminescence for optical signaling and illumination DOI Creative Commons
Chenghai Li, Qiguang He, Yang Wang

et al.

Nature Communications, Journal Year: 2022, Volume and Issue: 13(1)

Published: July 7, 2022

Biohybrid is a newly emerging and promising approach to construct soft robotics machines with novel functions, high energy efficiency, great adaptivity intelligence. Despite many unique advantages of biohybrid systems, it well known that most systems have relatively short lifetime, require complex fabrication process, only remain functional careful maintenance. Herein, we introduce simple method create highly robust power-free mechanoluminescence, by encapsulating dinoflagellates, bioluminescent unicellular marine algae, into elastomeric chambers. The dinoflagellates retain their intrinsic bioluminescence, which near-instantaneous light response mechanical forces. We demonstrate the robustness various geometries mechanoluminescent devices, as potential applications such visualizing external perturbations, deformation-induced illumination, optical signaling in dark environment. Our devices are ultra-sensitive fast time can maintain emission capability for weeks without special

Language: Английский

Citations

64
Vitrimer-based soft actuators with multiple responsiveness and self-healing ability triggered by multiple stimuli DOI Creative Commons
Yang Yang, Haomin Wang, Shuai Zhang

et al.

Matter, Journal Year: 2021, Volume and Issue: 4(10), P. 3354 - 3365

Published: Sept. 9, 2021

Language: Английский

Citations

62
Recent progress in the shape deformation of polymeric hydrogels from memory to actuation DOI Creative Commons
Baoyi Wu, Huanhuan Lu, Xiaoxia Le

et al.

Chemical Science, Journal Year: 2021, Volume and Issue: 12(19), P. 6472 - 6487

Published: Jan. 1, 2021

Shape deformation hydrogels, which are one of the most promising and essential classes stimuli-responsive polymers, could provide large-scale reversible under external stimuli.

Language: Английский

Citations

61
Biohybrid Micro- and Nanorobots for Intelligent Drug Delivery DOI Creative Commons
Jinhua Li, Lukáš Děkanovský, Bahareh Khezri

et al.

Cyborg and Bionic Systems, Journal Year: 2022, Volume and Issue: 2022

Published: Jan. 1, 2022

Biohybrid micro- and nanorobots are integrated tiny machines from biological components artificial components. They can possess the advantages of onboard actuation, sensing, control, implementation multiple medical tasks such as targeted drug delivery, single-cell manipulation, cell microsurgery. This review paper is to give an overview biohybrid for smart delivery applications. First, a wide range comprising different reviewed in detail. Subsequently, applications active introduced demonstrate how being exploited field medicine healthcare. Lastly, key challenges be overcome discussed pave way clinical translation application nanorobots.

Language: Английский

Citations

58
Toward a living soft microrobot through optogenetic locomotion control of Caenorhabditis elegans DOI
Xianke Dong, Sina Kheiri, Yangning Lu

et al.

Science Robotics, Journal Year: 2021, Volume and Issue: 6(55)

Published: June 23, 2021

The combination of microrobotics and optogenetics enables closed-loop locomotion control a living nematode worm.

Language: Английский

Citations

57
Advances in 3D Bioprinting DOI Creative Commons
Yongcong Fang,

Yuzhi Guo,

Tiankun Liu

et al.

Chinese Journal of Mechanical Engineering Additive Manufacturing Frontiers, Journal Year: 2022, Volume and Issue: 1(1), P. 100011 - 100011

Published: Feb. 16, 2022

Three-dimensional (3D) bioprinting has emerged as a promising approach for engineering functional tissues and organs by layer-by-layer precise positioning of biological materials, living cells, biochemical components. Compared with nonbiological printing, 3D involves additional complexities technical challenges owing to the processing such appropriate biomaterials that fulfill requirements both printability functionality. In this review, we first introduce development course bioprinting, highlighting innovative forms building blocks advances in enabling techniques bioprinting. We then summarize state-of-the-art advancements biomedical applications, including macroscale tissue or organ disease modeling, microphysiological systems, biobots, space. Despite rapid over past decades, most bioprinted constructs are still far from being suitable clinical translation, it is necessary field shift its focus shape mimicking towards functionality development. Therefore, provide our perspectives on burgeoning an emphasis maturation post printing translational applications at bedside.

Language: Английский

Citations

56
Electroconductive and Anisotropic Structural Color Hydrogels for Visual Heart‐on‐a‐Chip Construction DOI
Lingyu Sun, Zhuoyue Chen, Dongyu Xu

et al.

Advanced Science, Journal Year: 2022, Volume and Issue: 9(16)

Published: March 28, 2022

Heart-on-a-chip plays an important role in revealing the biological mechanism and developing new drugs for cardiomyopathy. Tremendous efforts have been devoted to heart-on-a-chip systems featuring simplified fabrication, accurate imitation microphysiological visuality. In this paper, authors present a novel electroconductive anisotropic structural color hydrogel by simply polymerizing non-close-packed colloidal arrays on super aligned carbon nanotube sheets (SACNTs) visualized construction. The generated consists of array-locked layer with brilliant one surface conductive methacrylated gelatin (GelMA)/SACNTs film other surface. It is demonstrated that morphology SACNTs could effectively induce alignment cardiomyocytes, conductivity contribute synchronous beating cardiomyocytes. Such consistent rhythm caused deformation substrates dynamic shifts reflection spectra whole hybrid hydrogels. More attractively, integration such cardiomyocyte-driven living hydrogels microfluidics, system more frequency has established cardiomyocyte sensing drug screening. results indicate are potential various biomedical applications.

Language: Английский

Citations

54