Chemistry - A European Journal,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Aug. 20, 2024
A
green
and
efficient
protocol
for
the
direct
monofluorination
of
unactivated
alkylarenes
under
visible-light
irradiation
has
been
developed,
without
any
extraneous
transition-metal
catalysts
or
photosensitizers.
This
method
is
compatible
with
a
broad
spectrum
functional
groups,
including
carboxylic
alcoholic
scaffolds,
mild
reaction
conditions.
Gram-scale
synthesis
fluorine-containing
pharmaceutical
analogue
was
successfully
executed,
underscoring
strategy's
reliability
practicality.
Furthermore,
mechanistic
studies
suggest
that
single-electron
transfer
mechanism
might
be
responsible
generation
benzylic
radicals
in
initiation
step.
Russian Chemical Reviews,
Journal Year:
2023,
Volume and Issue:
92(12), P. RCR5104 - RCR5104
Published: Dec. 1, 2023
After
the
appearance
of
green
chemistry
concept,
which
was
introduced
in
vocabulary
early
1990s,
its
main
statements
have
been
continuously
developed
and
modified.
Currently,
there
are
10–12
cornerstones
that
should
form
basis
for
an
ideal
chemical
process.
This
review
analyzes
accumulated
experience
achievements
towards
design
products
processes
reduce
or
eliminate
use
generation
hazardous
substances.
The
presents
views
leading
Russian
scientists
specializing
various
fields
this
subject,
including
homogeneous
heterogeneous
catalysis,
fine
basic
organic
synthesis,
electrochemistry,
polymer
chemistry,
based
on
bio-renewable
feedstocks
energetic
compounds
materials.
A
new
approach
to
quantitative
evaluation
environmental
friendliness
by
authors
is
described.
<br>
bibliography
includes
1761.
ACS Sustainable Chemistry & Engineering,
Journal Year:
2023,
Volume and Issue:
11(41), P. 14841 - 14865
Published: Sept. 15, 2023
The
development
of
cutting-edge
catalysts
is
critical
in
material
science
for
sustainable
development.
Though,
metals
have
always
been
used
catalysis
enabling
essential
chemicals,
but
their
use
not
considered
owing
to
the
high
cost,
toxicity,
and
poor
durability.
Nevertheless,
modern
focus
has
shifted
towards
metal
free
materials
due
leading
role
Carbon-based
nanomaterials
become
researchers
over
last
30
years
are
either
as
a
catalyst
support
or
metal-free
various
chemical
conversions.
They
highly
anticipated
state-of-the-art
specific
surface
area,
conductivity,
tunable
functional
groups.
This
account
summarizes
strategies
proposed
by
our
group
design
carbon
electrochemical
sensing,
biomass
valorization,
synthesis
value-added
chemicals.
Also,
"metal-free"
point-of-care
devices
fabricated
provide
affordable
healthcare
services
user
end.
designed
using
graphitic
nitride,
reduced
graphene
oxide,
Janus
2D
nanomaterials,
ultradispersed
diamonds,
nanotubes.
Their
efficacy
can
be
improved
building
composites
with
incorporating
defects.
Finally,
we
share
some
knowledge
insights
regarding
current
challenges
future
perspectives
this
emerging
field.
European Journal of Organic Chemistry,
Journal Year:
2024,
Volume and Issue:
27(7)
Published: Jan. 19, 2024
Abstract
A
Minisci‐type
carbamoylation
of
azauracils
was
developed
to
afford
6‐carbamoyl
in
yields
up
94
%.
In
this
transformation,
oxamic
acids
were
employed
as
the
carbamoyl
radical
sources
under
metal‐free
conditions.
It
features
high
atom
economy,
good
functional
group
compatibility
and
convenient
operation.
Journal of the American Chemical Society,
Journal Year:
2024,
Volume and Issue:
146(6), P. 4172 - 4177
Published: Feb. 5, 2024
Recently,
transition-metal
terminal
nonoxo
complexes
have
shown
a
remarkable
ability
to
activate
and
functionalize
C–H
bonds
via
proton-coupled
electron
transfer
(PCET).
Here
we
report
the
first
example
of
mononuclear
manganese(IV)
bis(fluoro)
complex
bearing
tetradentate
pyridinophane
ligand,
[MnIV(TBDAP)(F)2]2+
(3),
with
an
X-ray
single
crystal
structure
physicochemical
characterization.
The
has
very
high
reduction
potential
1.61
V
vs
SCE,
thereby
enabling
four-electron
oxidation
mesitylene
3,5-dimethylbenzaldehyde.
Kinetic
studies,
including
kinetic
isotope
effect
employment
other
toluene
derivatives,
reveal
(ET)-driven
PCET
in
bond
activation
by
3.
This
novel
metal
halide
intermediate
would
be
prominently
valuable
for
expanding
chemistry.
Nature Synthesis,
Journal Year:
2024,
Volume and Issue:
3(8), P. 1021 - 1030
Published: July 1, 2024
Abstract
Intramolecular
amination
of
remote
aliphatic
C–H
bonds
via
hydrogen-atom
transfer
reactions
has
become
a
powerful
tool
for
accessing
saturated
nitrogen-containing
heterocycles.
However,
the
formation
six-membered
rings
or
oxa-heterocycles
remains
formidable
challenge
Hofmann–Löffler–Freytag
reactions.
Here
we
show
how
by
simply
combining
bench-stable
(bis(trifluoroacetoxy)iodo)benzene
and
hexafluoroisopropanol
(HFIP)
can
switch
from
well-established
mechanism
to
different
versatile
reaction
pathway
that
enables
selective
C(
sp
3
)–H
bond
functionalization.
We
have
exploited
facile
radical
cations
single-electron
transfer,
in
presence
absence
light,
synthesize
pyrrolidines
piperidines,
including
drug-type
molecules,
along
with
O-heterocycles.
Experimental
computational
mechanistic
studies
support
two
distinct
pathways,
depending
on
electron
density
substrate,
which
HFIP
plays
multifunctional
role.
