Chemical Communications,
Journal Year:
2023,
Volume and Issue:
59(43), P. 6584 - 6587
Published: Jan. 1, 2023
We
synthesized
tetrasubstituted
olefins
regioselectively
and
stereoselectively
from
ynamides
internal
alkynes
with
sulfonyl
iodides
under
blue
LEDs
in
few
minutes.
The
key
features
are
being
metal-free,
easy
to
handle,
simple,
broad
scope,
environmentally
friendly.
Furthermore,
a
gram-scale
experiment
was
conducted,
the
corresponding
sulfonyl-iodinated
products
were
smoothly
altered
into
various
other
products.
Organic Chemistry Frontiers,
Journal Year:
2021,
Volume and Issue:
8(6), P. 1345 - 1363
Published: Jan. 1, 2021
This
review
is
devoted
to
highlighting
main
achievements
in
the
development
of
cascade
radical
cyclization
acceptors
for
synthesis
carbo-
and
heterocycles.
Organic Chemistry Frontiers,
Journal Year:
2020,
Volume and Issue:
7(19), P. 3100 - 3119
Published: Jan. 1, 2020
This
review
highlights
recent
progress
in
tandem
selenocyclization
and
tellurocyclization
with
alkenes
alkynes,
an
emphasis
on
the
scopes,
limitations
mechanisms
of
these
different
reactions.
Organic Letters,
Journal Year:
2023,
Volume and Issue:
25(22), P. 4208 - 4213
Published: May 30, 2023
A
novel
visible-light-promoted
selective
sulfonylation
and
selenylation
of
dienes
with
selenosulfonates
has
been
developed.
This
technology
provides
mild
access
to
a
wide
range
sulfonyl
benzo[b]azepinones
seleno-benzo[b]azepines.
Preliminary
mechanistic
studies
suggest
that
the
involves
radical
engaged
cascade
process,
is
accomplished
through
sequential
oxidation/electrophilic
cyclization
process.
The
large-scale
operation
late-stage
modification
experiment
reveal
promising
utility
this
protocol.
Advanced Synthesis & Catalysis,
Journal Year:
2024,
Volume and Issue:
366(6), P. 1220 - 1268
Published: Jan. 22, 2024
Abstract
Elaborated
molecular
architectures,
specifically
those
bearing
one
or
more
carbon
stereocenters,
stand
as
an
important
class
of
carbocyclic
and
heterocyclic
frameworks
because
they
are
frequently
occurring
core
structures
in
numerous
natural
products
biologically
active
pharmaceutical
molecules.
Over
the
past
few
decades,
development
versatile
synthetic
approaches
via
cascade
cyclization
reactions
1,6‐enynes
for
construction
a
series
fused
spiro
compounds
has
been
focus
great
deal
research
initiatives.
These
synthesis
strategies
peculiarly
fascinating
context
assembly
wide
array
molecules,
products,
agrochemicals,
functional
materials.
In
this
review,
recent
developments
transformations
with
diverse
coupling
reagents
summarized
since
2018,
which
could
be
divided
into
five
categories:
1)
Introduction;
2)
Transition
metal
catalyzed
1,6‐enynes;
3)
Metal‐free
4)
Visible‐light‐induced
5)
Electrocatalytic
1,6‐enynes.
Organic Letters,
Journal Year:
2024,
Volume and Issue:
26(31), P. 6652 - 6657
Published: July 26, 2024
We
report
a
visible-light-promoted
cyclization/sulfonylation
cascade
of
N-heterocycles
with
thianthrenium
salts
using
DABSO
as
the
SO2
surrogate.
This
method
features
excellent
functional
group
tolerance,
wide
substrate
scope,
and
late-stage
elaboration
bioactive
relevant
molecules.
Mechanistic
investigations
reveal
that
photoactive
electron
donor–acceptor
(EDA)
complexes
between
DABCO
are
capable
generation
aryl
radicals,
which
induce
following
insertion
by
attacking
DABSO,
thus
triggering
key
radical
cyclization
step.
Organic Letters,
Journal Year:
2021,
Volume and Issue:
23(7), P. 2754 - 2759
Published: March 19, 2021
A
direct
cascade
cyclization
of
3-aminoindazoles,
ynals,
and
accessible
chalcogens
facilitated
by
visible
light
has
been
developed.
series
fluoroactive
selenium/tellurium-substituted
pyrimido[1,2-b]-indazoles
were
easily
accessed
in
moderate
to
good
yields
with
a
broad
scope.
Furthermore,
we
surveyed
the
spectral
properties
selenide
prepared
this
method.
The Chemical Record,
Journal Year:
2021,
Volume and Issue:
21(10), P. 2739 - 2761
Published: March 3, 2021
Organoselenium
compounds
constitute
an
important
class
of
substances
with
applications
in
the
biological,
medicinal
and
material
sciences
as
well
modern
organic
synthesis,
attracting
considerable
attention
from
scientific
community.
Therefore,
construction
C-Se
bond
via
facile,
efficient
sustainable
strategies
to
access
complex
scaffolds
simple
substrates
are
appealing
hot
topic.
Visible
light
can
be
regarded
alternative
source
energy
is
associated
environmentally-friendly
processes.
Recently,
use
visible-light
mediated
seleno-functionalization
has
emerged
ideal
powerful
route
obtain
high-value
selenylated
products,
diminished
cost
waste.
This
approach,
involving
photo-excited
substrates/catalyst
single-electron
transfer
(SET)
between
presence
visible
been
successfully
used
versatile
direct
insertion
organoselenium
moieties
activated
unactivated
C(sp3
)-H,
C(sp2
C(sp)-H
bonds
C-heteroatom
bonds.
In
most
cases,
ease
operation
accessibility
(LEDs
or
commercial
CFL
bulbs)
makes
this
approach
more
attractive
than
traditional
strategies.
