Chemistry - A European Journal,
Journal Year:
2022,
Volume and Issue:
28(42)
Published: May 19, 2022
We
developed
time-atom
economic
regio-
and
chemoselective
sulfonyl
radical
triggered
5-exo-dig
cyclization
of
unactivated
1,6-enynes
with
halides
under
metal,
additive-free
reaction
conditions
to
achieve
highly
substituted
five-membered
heterocyclic
compounds.
This
transformation
creates
three
new
bonds,
such
as
C-SO2
,
C-C,
active
C-I/Br
bonds.
Importantly,
one-pot
protocols
produce
desired
products
directly
from
sodium
sulfinates
have
an
additional
advantage
minimising
chemical
waste,
saving
time,
simplifying
practical
aspects
compared
existing
protocols.
Organic Letters,
Journal Year:
2024,
Volume and Issue:
26(18), P. 3810 - 3815
Published: April 28, 2024
A
visible-light-driven
photocatalytic
protocol
is
established
for
the
diastereoselective
synthesis
of
pyrrolo[3,2,1-jk]carbazoles
via
a
radical-triggered
multicomponent
bicyclization
reaction
starting
from
readily
available
indole-tethered
1,6-enynes
and
α-benzyl-α-bromomalonates
under
mild
conditions.
This
approach
exhibits
wide
substrate
compatibility
excellent
tolerability
toward
various
functional
groups
boasts
benefit
efficient
ring
formation
chemical
bond
creation.
Green Chemistry,
Journal Year:
2021,
Volume and Issue:
23(17), P. 6652 - 6658
Published: Jan. 1, 2021
A
visible-light
driven
1,3-selenosulfonylation
of
vinyldiazo
compounds
with
selenosulfonates
provided
γ-seleno
allylic
sulfones
in
good
yields.
Control
experiments
showed
that
the
1,3-addition
proceeded
via
a
radical-chain
propagation
process.
Green Chemistry,
Journal Year:
2022,
Volume and Issue:
24(21), P. 8460 - 8465
Published: Jan. 1, 2022
Visible
light-driven,
a
radical-cascade
process
for
thioalkylation
of
quinoxalin-2(1
H
)-one
utilizing
styrene
and
aryl
disulfide
derivatives
has
been
discussed.
ChemCatChem,
Journal Year:
2022,
Volume and Issue:
14(14)
Published: May 2, 2022
Abstract
The
1,
n
‐enynes
are
potent
scaffolds
in
organic
synthesis,
providing
a
state‐of‐the‐art
approach
for
synthesizing
various
acyclic
and
carbo‐
heterocyclic
compounds.
Radical
cascade
cyclization
C−H
functionalization
of
have
gained
immense
attention
the
synthetic
community.
Significant
advancement
this
field
has
been
developed
over
years,
employing
harsh
expensive
metal
catalysts
usually
associated
with
intense
product
purification
unwanted
side‐products.
In
context,
advent
visible
light
photocatalysis
as
mild
efficient
area
is
welcome
step.
Herein,
we
provide
an
exclusive
overview
recent
developments
light‐assisted
manipulation
‐enynes.
We
classified
review
into
1,3‐,
1,4‐,
1,5‐,
1,6‐,
1,7‐,
1,8‐enynes,
well
dienyne,
enediyne‐based
reactions.
Chemistry - A European Journal,
Journal Year:
2022,
Volume and Issue:
28(42)
Published: May 19, 2022
We
developed
time-atom
economic
regio-
and
chemoselective
sulfonyl
radical
triggered
5-exo-dig
cyclization
of
unactivated
1,6-enynes
with
halides
under
metal,
additive-free
reaction
conditions
to
achieve
highly
substituted
five-membered
heterocyclic
compounds.
This
transformation
creates
three
new
bonds,
such
as
C-SO2
,
C-C,
active
C-I/Br
bonds.
Importantly,
one-pot
protocols
produce
desired
products
directly
from
sodium
sulfinates
have
an
additional
advantage
minimising
chemical
waste,
saving
time,
simplifying
practical
aspects
compared
existing
protocols.
