The Chemical Record,
Journal Year:
2021,
Volume and Issue:
21(9), P. 2585 - 2600
Published: April 8, 2021
Progress
in
electroorganic
synthesis
is
linked
to
innovation
of
new
synthetic
reactions
with
impact
on
medicinal
chemistry
and
drug
discovery
the
desire
minimise
waste
provide
energy-efficient
chemical
transformations
for
future
industrial
processes.
Paired
electrosynthetic
processes
that
combine
use
both
anode
cathode
(convergent
or
divergent)
minimal
(or
without)
intentionally
added
electrolyte
need
additional
reagents
are
growing
interest.
In
this
overview,
recent
progress
developing
paired
electrolytic
surveyed.
The
discussion
focuses
electrosynthesis
technology
proven
value
preparation
small
molecules.
Reactor
types
contrasted
concept
translating
light-energy
driven
photoredox
into
highlighted
as
a
newly
emerging
trend.
Organic Chemistry Frontiers,
Journal Year:
2021,
Volume and Issue:
8(6), P. 1132 - 1142
Published: Jan. 1, 2021
Triarylamines
are
demonstrated
as
novel,
tunable
electroactivated
photocatalysts
that
use
dispersion
precomplexation
to
harness
the
full
potential
of
visible
photon
(>4.0
V
vs.
SCE)
in
anti-Kasha
photo(electro)chemical
super-oxidations
arenes.
Chemical Society Reviews,
Journal Year:
2022,
Volume and Issue:
51(10), P. 3898 - 3925
Published: Jan. 1, 2022
This
manuscript
reviews
for
the
first
time
developments
at
interface
between
organic
electrosynthesis
and
single-atom
catalysis,
highlighting
advantages
in
shifting
from
a
batch
to
flow
production.
Advanced Materials,
Journal Year:
2023,
Volume and Issue:
35(14)
Published: Feb. 17, 2023
With
the
ultimate
atomic
utilization,
well-defined
configuration
of
active
sites
and
unique
electronic
properties,
catalysts
with
single-atom
(SASs)
exhibit
appealing
performance
for
electrocatalytic
green
hydrogen
generation
from
water
splitting
further
utilization
via
hydrogen-oxygen
fuel
cells,
such
that
a
vast
majority
synthetic
strategies
toward
SAS-based
(SASCs)
are
exploited.
In
particular,
room-temperature
electrosynthesis
under
atmospheric
pressure
offers
novel,
safe,
effective
route
to
access
SASs.
Herein,
recent
progress
in
ambient
SASs
sustainable
future
opportunities
discussed.
A
systematic
summary
is
started
on
three
kinds
electrochemically
routes
SASs,
including
electrochemical
etching
(ECE),
direct
electrodeposition
(DED),
leaching-redeposition
(ELR),
associated
advanced
characterization
techniques.
Next,
their
applications
energy
conversion
evolution
reaction,
oxygen
overall
splitting,
reduction
reaction
reviewed.
Finally,
brief
conclusion
remarks
challenges
regarding
development
high-performance
cost-effective
SASCs
many
other
presented.
Chemical Society Reviews,
Journal Year:
2023,
Volume and Issue:
52(23), P. 8106 - 8125
Published: Jan. 1, 2023
This
tutorial
review
delves
into
the
unique
advantages
of
electrochemistry
in
context
asymmetric
catalysis,
first
providing
a
brief
introduction
to
electrosynthesis,
then
exploring
representative
case
studies
with
mechanistic
focus.
Science,
Journal Year:
2024,
Volume and Issue:
384(6696), P. 670 - 676
Published: May 9, 2024
Electrochemistry
offers
a
sustainable
synthesis
route
to
value-added
fine
chemicals
but
is
often
constrained
by
competing
electron
transfer
between
the
electrode
and
redox-sensitive
functionalities
distinct
from
target
site.
Here,
we
describe
an
ion-shielding
heterogeneous
photoelectrocatalysis
strategy
impose
mass-transfer
limitations
that
invert
thermodynamically
determined
order
of
transfer.
This
showcased
enable
decarboxylative
trifluoromethylation
sensitive
(hetero)arenes
using
trifluoroacetate,
inexpensive
yet
relatively
inert
trifluoromethyl
group
(CF
Green Chemistry,
Journal Year:
2020,
Volume and Issue:
22(15), P. 4849 - 4870
Published: Jan. 1, 2020
Herein,
electrochemical
annulations
involving
mediators
and
mediator-free
conditions
have
been
discussed.
Also,
the
use
of
sacrificial
electrodes
has
explored.
Advanced Synthesis & Catalysis,
Journal Year:
2021,
Volume and Issue:
363(22), P. 5047 - 5071
Published: Oct. 1, 2021
Abstract
Electrochemical
synthesis
offers
a
mild,
simple,
and
efficient
tool
for
the
preparation
of
interesting
useful
molecules,
thus
eluding
severe
chemical
oxidizing
reducing
agents
used
in
conventional
synthetic
methods.
In
particular,
electrochemical
C−H
activation
is
expected
to
play
an
important
role
direct
functionalization
heterocyclic
compounds.
Over
past
few
decades,
research
interest
imidazopyridine
indazole
has
increased
significantly
due
their
multipurpose
uses
medicinal
industrial
chemistry.
Therefore,
structural
modification
these
heterocycles
using
electro‐oxidation
become
one
topics
among
organic
chemistry
recent
time.
This
review
provides
comprehensive
discussion
indazoles
imidazopyridines
published
so
far.
A
summary
current
challenges
future
direction
development
green
methods
also
presented.
magnified
image
Advanced Synthesis & Catalysis,
Journal Year:
2020,
Volume and Issue:
362(23), P. 5219 - 5237
Published: Oct. 13, 2020
Abstract
The
importance
of
fluorinated
organic
molecules
in
drugs
and
pharmaceuticals
led
to
the
development
several
synthetic
methods
for
introducing
fluorine
into
bioactive
trifluoromethylation
is
one
key
approaches
same.
Electrochemical
synthesis
has
emerged
as
most
sustainable,
green
strategies
recent
years
new
developments
electroorganic
also
focus
on
electrochemical
compounds.
A
considerable
number
reports
have
appeared
literature
this
review
surveys
all
reactions.
This
highly
sustainable
trifluoromethylating
protocol
will
emerge
further
soon
pave
way
more
energy‐efficient
protocols.
magnified
image
Journal of the American Chemical Society,
Journal Year:
2021,
Volume and Issue:
144(1), P. 23 - 41
Published: Dec. 30, 2021
Although
electrochemical
strategies
for
small-molecule
synthesis
are
flourishing,
this
technology
has
yet
to
be
fully
exploited
the
mild
and
chemoselective
modification
of
peptides
proteins.
With
growing
number
diverse
peptide
natural
products
being
identified
emergence
modified
proteins
as
therapeutic
diagnostic
agents,
methods
stand
alluring
prospects
harnessing
reactivity
polypeptides
build
molecular
complexity.
As
a
inherently
tunable
reaction
platform,
electrochemistry
is
arguably
well-suited
overcome
chemo-
regioselectivity
issues
which
limit
existing
bioconjugation
strategies.
This
Perspective
will
showcase
recently
developed
approaches
protein
modification.
The
article
also
highlights
wealth
untapped
opportunities
production
homogeneously
biomolecules,
with
an
eye
toward
realizing
enormous
potential
chemistry.
