Asian Journal of Organic Chemistry,
Journal Year:
2021,
Volume and Issue:
10(11), P. 2820 - 2847
Published: Aug. 30, 2021
Abstract
Electro‐organic
reactions
are
now
considered
as
one
of
the
most
efficient
and
environmentally
benign
methodologies
to
synthesize
highly
functionalized
motifs
like
difunctionalized
unsaturated
compounds
from
readily
available
substrates.
Excellent
regioselectivity,
functional
group
tolerance
broad
range
substrates
main
advantages
electrochemical
difunctionalization
reactions.
Alkenes
alkynes
accept
radical
or
ionic
derivatives
which
makes
it
vital
precursors
for
synthesis
industrially
relevant
biologically
active
molecules
through
difunctionalization.
This
review
aims
provide
readers
an
excellent
coverage
different
alkenes
such
1,2‐homodifunctionalization,
1,2‐heterodifunctionalization,
rearrangement,
ipso
‐migration,
cyclization
dehydrogenative
annulation
The Chemical Record,
Journal Year:
2020,
Volume and Issue:
20(12), P. 1530 - 1552
Published: Oct. 5, 2020
Abstract
Organophosphorus
chemistry
is
a
broad
field
with
multi‐dimensional
applications
in
research
area
of
organic,
biology,
drug
design
and
agrochemicals.
Conventional
methods
have
been
adopted
extensively
to
access
phosphorylated
compounds
that
rely
on
the
use
toxic,
moisture
sensitive
phosphorylating
agents
occur
presence
oxidants,
catalysts,
as
well
high
temperatures
harsh
conditions
are
required
for
complete
transformations.
However,
recent
progress
has
made
phosphorylation
reactions
using
electricity
introduce
green
sustainable
synthetic
procedures.
These
can
be
performed
at
mild
proceed
excellent
atom
economy.
Herein,
we
targeted
electrochemical
generation
new
bonds
such
C(sp
3
)
−P,
2
O−P,
N−P,
S−P
Se−P.
This
review
aimed
offer
an
overview
developments
methodology
easy
organophosphorus
electrochemistry.
The Journal of Organic Chemistry,
Journal Year:
2020,
Volume and Issue:
85(23), P. 15708 - 15716
Published: Nov. 23, 2020
A
transition-metal-
and
oxidant-free
electrochemical
strategy
for
radical
fluoroalkylation
of
vinyl
azides
was
developed.
The
reaction
carried
out
under
mild
conditions
by
using
inexpensive
bench-stable
RfSO2Na
(Rf
=
CF3,
CF2H)
as
fluorination
reagents.
Depending
on
the
starting
material,
both
cyclization
dearomatization
products
could
be
obtained.
This
method
provides
a
green
safe
approach
to
synthesize
fluorinated
nitrogen
heterocycles.
The Journal of Organic Chemistry,
Journal Year:
2021,
Volume and Issue:
86(3), P. 2593 - 2601
Published: Jan. 11, 2021
A
green
and
practical
electrochemical
method
for
the
synthesis
of
C-3-sulfonated
benzothiophenes
from
2-alkynylthioanisoles
sodium
sulfinates
was
developed
under
oxidant-
catalyst-free
conditions.
Moderate
to
good
yields
sulfonated
bearing
important
useful
functional
groups
have
been
achieved
at
a
constant
current.
Preliminary
mechanistic
studies
indicated
tandem
radical
addition-cyclization
pathway.
Moreover,
protocol
is
easy
scale
up
exhibits
reaction
efficiency.
Asian Journal of Organic Chemistry,
Journal Year:
2021,
Volume and Issue:
10(11), P. 2820 - 2847
Published: Aug. 30, 2021
Abstract
Electro‐organic
reactions
are
now
considered
as
one
of
the
most
efficient
and
environmentally
benign
methodologies
to
synthesize
highly
functionalized
motifs
like
difunctionalized
unsaturated
compounds
from
readily
available
substrates.
Excellent
regioselectivity,
functional
group
tolerance
broad
range
substrates
main
advantages
electrochemical
difunctionalization
reactions.
Alkenes
alkynes
accept
radical
or
ionic
derivatives
which
makes
it
vital
precursors
for
synthesis
industrially
relevant
biologically
active
molecules
through
difunctionalization.
This
review
aims
provide
readers
an
excellent
coverage
different
alkenes
such
1,2‐homodifunctionalization,
1,2‐heterodifunctionalization,
rearrangement,
ipso
‐migration,
cyclization
dehydrogenative
annulation
