The Journal of Organic Chemistry,
Journal Year:
2020,
Volume and Issue:
85(20), P. 12843 - 12855
Published: Sept. 21, 2020
Chiral
phosphoric
acid
based
organocatalysis
and
visible-light
photocatalysis
have
both
emerged
as
promising
technologies
for
the
sustainable
production
of
fine
chemicals.
In
this
context,
we
envisioned
design
synthesis
a
new
class
chimeric
catalytic
entities
that
would
feature
capabilities.
Given
their
multitask
nature,
such
catalysts
be
particularly
attractive
development
transformations,
tandem
processes
in
particular.
Toward
goal,
several
BINOL-based
chiral
backbones
presenting
one
or
two
visible-light-sensitive
thioxanthone
moieties
been
prepared
studied.
The
utility
these
photoactive
organocatalysts
is
then
demonstrated
enantioselective
three-component
electrophilic
amination
enecarbamates.
Of
note,
C1-symmetric
organo/photocatalyst
has
shown
better
activity
than
those
C2
symmetry.
Journal of the American Chemical Society,
Journal Year:
2022,
Volume and Issue:
144(9), P. 4206 - 4213
Published: Feb. 22, 2022
Stereoinduction
in
complex
organic
reactions
often
involves
the
influence
of
multiple
stereocontrol
elements.
The
interaction
among
these
can
result
observation
significant
cooperative
effects
that
afford
different
rates
and
selectivities
between
matched
mismatched
sets
stereodifferentiating
chiral
elucidation
matched/mismatched
ground-state
chemical
was
a
critically
important
theme
maturation
modern
stereocontrolled
synthesis.
development
robust
methods
for
control
photochemical
reactions,
however,
is
relatively
recent
development,
similar
stereocontrolling
excited-state
enantioselective
photoreactions
have
not
previously
been
documented.
Herein,
we
describe
tandem
photocatalyst/Brønsted
acid
strategy
highly
[2
+
2]
photocycloadditions
vinylpyridines.
Importantly,
catalyst
pairs
exhibit
reaction
enantioselectivities
across
range
coupling
partners.
We
observe
no
evidence
interactions
catalysts
conclude
arise
from
their
behavior
transient
assembly.
These
results
suggest
might
be
other
classes
dual-catalytic
reactions.
Journal of the American Chemical Society,
Journal Year:
2022,
Volume and Issue:
144(42), P. 19207 - 19218
Published: Oct. 14, 2022
With
the
rapid
development
of
photoredox
catalysis,
numerous
concepts
for
asymmetric
induction
were
successfully
and
broadly
adapted
from
polar
two-electron
transformations
to
radical
chemistry.
While
this
applies
organocatalysis
or
transition
metal
chemistry,
ion-pairing
catalysis
remains
a
niche
application
within
light-driven
reactions
today.
This
perspective
gives
an
overview
recent
examples,
strategies,
their
in
stereoselective
at
interface
photo(redox)
catalysis.
Frontiers in Catalysis,
Journal Year:
2022,
Volume and Issue:
1
Published: Jan. 10, 2022
In
the
last
years,
there
were
two
fields
that
experienced
an
astonishing
growth
within
biocatalysis
community:
photobiocatalysis
and
applications
of
flow
technology
to
catalytic
processes.
Therefore,
it
is
not
a
surprise
combination
these
research
areas
also
gave
place
several
recent
interesting
articles.
However,
best
our
knowledge,
no
review
article
covering
advances
was
published
so
far.
Within
this
review,
we
present
very
developments
in
field
continuous
flow,
discuss
different
practical
features
state-of-the
art
photobioreactors
lastly,
some
future
perspectives
field.
Angewandte Chemie International Edition,
Journal Year:
2021,
Volume and Issue:
61(11)
Published: Dec. 22, 2021
Here
we
report
a
practical,
highly
enantioselective
photoredox
allylation
of
aldehydes
mediated
by
chiral
nickel
complexes
with
commercially
available
allyl
acetate
as
the
allylating
agent.
The
methodology
allows
clean
stereoselective
in
good
to
excellent
yields
and
up
93
%
e.e.
using
catalytic
amount
NiCl2
(glyme)
presence
aminoindanol-derived
bis(oxazoline)
ligand.
system
is
constituted
organic
dye
3DPAFIPN
Hantzsch's
ester
sacrificial
reductant.
reaction
proceeds
under
visible-light
irradiation
(blue
LEDs,
456
nm)
at
8-12
°C.
Compared
other
published
procedures,
no
metal
reductants
(such
Zn
or
Mn),
additives
(e.g.
CuI)
air-sensitive
Ni(COD)2
are
necessary
for
this
reaction.
Accurate
DFT
calculations
photophysical
experiments
have
clarified
mechanistic
picture
Current Opinion in Green and Sustainable Chemistry,
Journal Year:
2021,
Volume and Issue:
31, P. 100496 - 100496
Published: April 22, 2021
Using
light
for
biocatalysis
is
a
relatively
new
and
expanding
research
field.
Because
of
the
ever-increasing
number
publications,
this
review
highlights
developments
in
field
photobiocatalysis
published
past
two
years.
We
introduce
topic
briefly
list
most
articles
appeared
so
far.
Afterward,
we
devote
special
attention
to
interesting
relevant
key
vitro
photobiocatalysis,
briefly,
describe
novel
discoveries
photobiocatalytic
cascades
strict
light-dependent
enzymes.
Finally,
outline
next
decade
conclusions
future
perspectives
part.
ChemCatChem,
Journal Year:
2023,
Volume and Issue:
15(21)
Published: Aug. 16, 2023
Abstract
Visible
light‐induced
photocatalysis
has
been
widely
investigated,
which
offers
exciting
opportunities
to
build
new
catalytic
platforms
that
are
unattainable
under
ground
state
conditions.
Asymmetric
a
longstanding
challenge
due
the
high
reactivity
of
photogenerated
intermediates
leading
strong
background
reaction.
Carbonyl
group
is
an
important
fundamental
scaffold
in
organic
synthesis.
The
photocatalytic
asymmetric
transformations
carbonyl
compounds
for
synthesizing
enantioenriched
secondary
and
tertiary
alcohols
significant
value
but
remain
problematic.
Even
so,
series
intriguing
works
concerning
this
topic
have
reported
recent
year.
This
review
summarizes
advances
area,
mainly
dividing
into
single
synergetic
catalyst
systems,
mechanism
each
reaction
discussed.
Chemical Communications,
Journal Year:
2021,
Volume and Issue:
57(15), P. 1911 - 1914
Published: Jan. 1, 2021
A
new
and
general
photocatalytic
Kharasch-type
addition/1,5-(SN′′)-substitution
cascade
of
1,7-diynes
with
alkyl
halides
such
as
BrCCl3and
CBr4was
reported
for
the
first
time,
producing
65
hitherto
unreported
β-gem-dihalovinyl
ketones/aldehydes
moderate
to
excellent
yields.
ACS Catalysis,
Journal Year:
2022,
Volume and Issue:
12(20), P. 13065 - 13074
Published: Oct. 12, 2022
The
potential
of
electron
donor–acceptor
(EDA)
complex
photochemistry
has
recently
been
recognized
in
visible-light-induced
photocatalyst-free
radical
reactions.
design
catalytic
asymmetric
reactions
driven
by
EDA
complexes
remains
a
substantial
challenge,
and
existing
examples
are
limited
to
sole
activation
modes
with
aminocatalysts
or
phase-transfer
catalysts.
Herein,
we
demonstrate
that
chiral
bifunctional
hydrogen-bonding
catalysis
can
realize
the
reaction
an
via
dual
afford
vicinal
tertiary
stereocenters
at
β,γ-positions
pyridines
high
yields
good
enantio-
diastereoselectivities.
Mechanistic
studies
suggest
crucial
success
factor
for
this
transformation
is
use
phosphoric
acid
(CPA),
which
not
only
accelerates
situ
formation
aggregates
between
redox-active
esters
(RAEs)
Hantzsch
(HEs)
but
also
provides
proper
substrate
induction.
