Recent Advances in Zwitterionic Hydrogels: Preparation, Property, and Biomedical Application

Gels, Journal Year: 2022, Volume and Issue: 8(1), P. 46 - 46

Published: Jan. 7, 2022

Nonspecific protein adsorption impedes the sustainability of materials in biologically related applications. Such activates immune system by quick identification allogeneic and triggers a rejection, resulting rapid failure implant drugs. Antifouling have been rapidly developed past 20 years, from natural polysaccharides (such as dextran) to synthetic polymers polyethylene glycol, PEG). However, recent studies shown that traditional antifouling materials, including PEG, still fail overcome challenges complex human environment. Zwitterionic are class contain both cationic anionic groups, with their overall charge being neutral. Compared PEG zwitterionic much stronger hydration, which is considered most important factor for antifouling. Among hydrogels excellent structural stability controllable regulation capabilities various biomedical scenarios. Here, we first describe mechanism structure materials. Following preparation property hydrogels, advances applications reviewed.

Language: Английский

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Curcumin-loaded alginate hydrogels for cancer therapy and wound healing applications: A review

International Journal of Biological Macromolecules, Journal Year: 2023, Volume and Issue: 232, P. 123283 - 123283

Published: Jan. 17, 2023

Hydrogels have emerged as a versatile platform for numerous biomedical application due to their ability absorb huge quantity of biofluids. In order design hydrogels, natural polymers are an attractive option owing biocompatibility and biodegradability. Due abundance in occurrence, cost effectiveness, facile crosslinking approaches, alginate has been extensively investigated fabricate hydrogel matrix. Management cancer chronic wounds always challenge pharmaceutical healthcare sector. both cases, curcumin shown significant improvement effectiveness. However, the innate restraints like poor bioavailability, hydrophobicity, rapid systemic clearance associated with restricted its clinical translations. The current review explores cascade research around encapsulated matrix wound healing therapy. focus is emphasize mechanistic effects fate inside cells. Further, discusses different approaches designed loaded hydrogels along parameters that regulates release behavior. Finally, concluded on some key aspect increasing efficacy these novel strategies further develop multifacet applications.

Language: Английский

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Poly(Ionic Liquid) Double‐Network Elastomers with High‐Impact Resistance Enhanced by Cation‐π Interactions

Advanced Materials, Journal Year: 2023, Volume and Issue: 36(13)

Published: Dec. 27, 2023

Abstract With the continuous development of impact protection materials, lightweight, high‐impact resistance, flexibility, and controllable toughness are required. Here, tough impact‐resistant poly(ionic liquid) (PIL)/poly(hydroxyethyl acrylate) (PHEA) double‐network (DN) elastomers constructed via multiple cross‐linking polymer networks cation‐π interactions PIL chains. Benefiting from strong noncovalent cohesion achieved by in chains, prepared DN exhibit extraordinary compressive strength (95.24 ± 2.49 MPa) (55.98 0.66 MJ m −3 ) under high‐velocity load (5000 s −1 ). The synthesized elastomer combines flexibility to protect fragile items impact. This strategy provides a new research idea field next generation safety protective materials.

Language: Английский

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Stimuli-responsive coordination polymers toward next-generation smart materials and devices

eScience, Journal Year: 2024, Volume and Issue: 4(3), P. 100231 - 100231

Published: Jan. 21, 2024

Stimuli-responsive coordination polymers (CPs) are among one of the most prolific research areas in developing next-generation functional materials. Their capability being accurately excited by particular external changes with pre-determined and observable/characterizable behaviours correspond, so called "stimuli" "responsive". Abundant types CP compounds, especially metal-organic frameworks (MOFs), rocketing interest owing to their compositional diversity, structural tunability, essence highly engineerable functionality. This present review is aimed sketch several common stimulation corresponding responses for CPs, accompanied broad logic mechanisms underneath. And further from aspect material revolution, some representative progresses together latest advances CP-based materials various fields covered attempt display a broader picture towards possible prospects this topic.

Language: Английский

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Superwetting metal mesh membranes for oil/water separation: A comprehensive review

Separation and Purification Technology, Journal Year: 2025, Volume and Issue: unknown, P. 132016 - 132016

Published: Feb. 1, 2025

Language: Английский

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Poly (vinyl alcohol)-alginate as potential matrix for various applications: A focused review

Carbohydrate Polymers, Journal Year: 2021, Volume and Issue: 277, P. 118881 - 118881

Published: Nov. 11, 2021

Language: Английский

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Modifications of Polymers through the Addition of Ultraviolet Absorbers to Reduce the Aging Effect of Accelerated and Natural Irradiation

Polymers, Journal Year: 2021, Volume and Issue: 14(1), P. 20 - 20

Published: Dec. 22, 2021

The photooxidative degradation process of plastics caused by ultraviolet irradiation leads to bond breaking, crosslinking, the elimination volatiles, formation free radicals, and decreases in weight molecular weight. Photodegradation deteriorates both mechanical physical properties affects their predicted life use, particular for applications harsh environments. Plastics have many benefits, while on other hand, they numerous disadvantages, such as photodegradation photooxidation environments release toxic substances due leaching some components, which a negative effect living organisms. Therefore, attention is paid design use safe, plastic, stabilizers that do not pose danger environment if released. Plastic photostabilizers act efficient light screeners (absorbers or pigments), excited-state deactivators (quenchers), hydroperoxide decomposers, radical scavengers. Ultraviolet absorbers are cheap produce, can be used low concentrations, mix well with polymers produce homogenous matrix, alter color polymers. Recently, polyphosphates, Schiff bases, organometallic complexes were synthesized potential polymeric materials. They reduced damage accelerated natural aging, was confirmed inspecting surface morphology irradiated films. For example, atomic force microscopy revealed roughness factor polymers’ surfaces improved significantly presence absorbers. In addition, investigation using scanning electron showed high degree homogeneity appearance pores different size shape. current work surveys first time newly synthesized, additives enhance photostability materials and, particular, polyvinyl chloride polystyrene, based mainly our own recent field.

Language: Английский

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Toward enabling manufacturing paradigm of 4D printing of shape memory materials: Open literature review

European Polymer Journal, Journal Year: 2022, Volume and Issue: 168, P. 111106 - 111106

Published: March 7, 2022

Language: Английский

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Dynamic polymeric materials based on reversible B–O bonds with dative boron–nitrogen coordination

SmartMat, Journal Year: 2023, Volume and Issue: 4(3)

Published: Feb. 21, 2023

Abstract To minimize the environmental pollution caused by polymeric waste, materials based dynamic chemistry have attracted extensive attention around world. Various covalent bonds or noncovalent interactions been employed to design multifunctional polymers with recyclability, reprocessablility, and sustainability. Among them, on reversible boron–oxygen (B–O) widely investigated because of their unique properties. Particularly, lots scientists demonstrated that combination boron–nitrogen (B–N) coordination can effectively accelerate dynamicity as well enhance stability B–O bonds. Therefore, numerous containing dative B–N designed synthesized in recent years. These exhibit excellent versatility great potential for diverse applications such biosensors, battery electrolytes, artificial skins. This review provides an overview comprehensive influence organoboron species highlights developments area constructing boron‐containing this interesting linkage. The guidelines, existing challenges, future perspectives burgeoning field are discussed proposed.

Language: Английский

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Cation–π Interaction-Enhanced Self-Healing Injectable Hydrogels for Gastric Perforation Repair

ACS Applied Materials & Interfaces, Journal Year: 2024, Volume and Issue: 16(28), P. 35887 - 35897

Published: July 4, 2024

Surgical operations are the preferred treatment for gastric perforation (GP) but incur postoperative complications such as gastrointestinal adhesions and bacterial infections, leading to inefficient wound healing serious that may even threaten life of patient. Developing hydrogel dressings capable adapting environment (acid) decreasing visceral infections after GP is crucial. In this article, we developed an injectable, self-healing using cation–π interactions between protonated amines aromatic rings under acidic conditions explored it repair. The hydrogels demonstrate exceptional capabilities can be effectively tailored environment. addition, demonstrated significant efficacy in preventing adhesion, reducing inflammation, promoting angiogenesis, facilitating a rat model. This novel demonstrates adaptability environment, rendering highly promising potential applications trauma healing.

Language: Английский

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