Ligand-Based Shielding Effect Induced Efficient Near-Infrared Electrochemiluminescence of Gold Nanoclusters and Its Sensing Application DOI
Yamin Nie, Yue Zhang,

Weiwei Cao

et al.

Analytical Chemistry, Journal Year: 2023, Volume and Issue: 95(17), P. 6785 - 6790

Published: April 20, 2023

Preparing high-efficiency ECL gold nanoclusters (Au NCs) still faces a serious challenge due to the poor stability of co-reactant radicals in aqueous media. Herein, we report ligand-based shielding effect induced record near-infrared (λmax = 786 nm) efficiency β-cyclodextrin-protected Au NCs (β-CD-Au with triethylamine (TEA) as co-reactant. The ligand β-CD-Au matched hydrophobic cavity could encapsulate TEA driven by host-guest chemistry, which not only allows generation TEA• diminish environmental exposure, thus reducing quenching dissolved oxygen, water, etc., but also shortens charge transfer pathway without extensive chemical modification. Density functional theory, 1H NMR spectra, electron paramagnetic resonance, and differential pulse voltammetry studies revealed that β-CD significantly increased reactivity TEA. More importantly, stark contrast those traditional ligand-protected NCs, enhanced 321-fold versus BSA-Au 153-fold ATT-Au 19-fold GSH-Au 1 mM Therefore, this work provides an in-depth understanding crucial role ligands enhancing active radical for metal immensely stimulate their promising applications. Using emitters, "signal off" sensing platform was constructed detect noradrenaline model target lower detection limit 0.91 nM.

Language: Английский

Recent advances in electrochemiluminescence immunosensing DOI Creative Commons
Jing Yu, Dalibor M. Stanković, Jasmina Vidić

et al.

Sensors & Diagnostics, Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 1, 2024

Herein, we review the recent developments and applications of ECL for immunosensing in different areas, such as detection biomarkers, bead-based bacteria cell analysis, provide future perspectives new developments.

Language: Английский

Citations

6
Electrochemiluminescence Microscopy of Cells: Essential Role of Surface Regeneration DOI
Dongni Han, Bertrand Goudeau, Dechen Jiang

et al.

Analytical Chemistry, Journal Year: 2020, Volume and Issue: 93(3), P. 1652 - 1657

Published: Dec. 29, 2020

Electrochemiluminescence (ECL) microscopy is successfully applied to image cells, micro-/nano-objects, and electrochemical processes at electrode surfaces. The classic ECL tandem system composed of the [Ru(bpy)3]2+ luminophore with very efficient tripropylamine (TPA) coreactant. dramatic decrease signal observed when recording successive images constitutes a key limitation for development microscopy. Herein, we investigated progressive Chinese hamster ovary (CHO) cells. plasma membranes CHO cells were labeled derivative, recorded using TPA We demonstrate that loss related step because lower oxidation current. tested cathodic regenerative treatment surface, which allowed us restore initial intensity thus record sequence without any vanishing light signal. approach presented here an essential

Language: Английский

Citations

45
Catalytic route electrochemiluminescence microscopy of cell membranes with nitrogen-doped carbon dots as nano-coreactants DOI
Cheng Ma,

Minxuan Wang,

Huifang Wei

et al.

Chemical Communications, Journal Year: 2021, Volume and Issue: 57(17), P. 2168 - 2171

Published: Jan. 1, 2021

Catalytic route electrochemiluminescence microscopy enables us to image upper cell membranes with a vertical resolution mode by using nitrogen-doped carbon dots as nano-coreactants and labels.

Language: Английский

Citations

39
Recent advances in mechanistic understanding and analytical methodologies of the electrochemiluminescence of tris(2,2′-bipyridine)ruthenium(II) and tri-n-propylamine DOI
Emily Kerr, Egan H. Doeven, Paul S. Francis

et al.

Current Opinion in Electrochemistry, Journal Year: 2022, Volume and Issue: 35, P. 101034 - 101034

Published: May 3, 2022

Language: Английский

Citations

27
Ligand-Based Shielding Effect Induced Efficient Near-Infrared Electrochemiluminescence of Gold Nanoclusters and Its Sensing Application DOI
Yamin Nie, Yue Zhang,

Weiwei Cao

et al.

Analytical Chemistry, Journal Year: 2023, Volume and Issue: 95(17), P. 6785 - 6790

Published: April 20, 2023

Preparing high-efficiency ECL gold nanoclusters (Au NCs) still faces a serious challenge due to the poor stability of co-reactant radicals in aqueous media. Herein, we report ligand-based shielding effect induced record near-infrared (λmax = 786 nm) efficiency β-cyclodextrin-protected Au NCs (β-CD-Au with triethylamine (TEA) as co-reactant. The ligand β-CD-Au matched hydrophobic cavity could encapsulate TEA driven by host-guest chemistry, which not only allows generation TEA• diminish environmental exposure, thus reducing quenching dissolved oxygen, water, etc., but also shortens charge transfer pathway without extensive chemical modification. Density functional theory, 1H NMR spectra, electron paramagnetic resonance, and differential pulse voltammetry studies revealed that β-CD significantly increased reactivity TEA. More importantly, stark contrast those traditional ligand-protected NCs, enhanced 321-fold versus BSA-Au 153-fold ATT-Au 19-fold GSH-Au 1 mM Therefore, this work provides an in-depth understanding crucial role ligands enhancing active radical for metal immensely stimulate their promising applications. Using emitters, "signal off" sensing platform was constructed detect noradrenaline model target lower detection limit 0.91 nM.

Language: Английский

Citations

15