Molecules,
Journal Year:
2022,
Volume and Issue:
27(17), P. 5671 - 5671
Published: Sept. 2, 2022
N-heterocyclic
compounds,
such
as
quinazolinone
derivatives,
have
significant
biological
activities.
Nowadays,
the
demand
for
environmentally
benign,
sustainable
processes
increases,
application
of
compounds
from
renewable
sources,
easily
separable
heterogeneous
catalysts
and
efficient,
alternative
activation
methods
is
great
importance.
In
this
study,
we
developed
a
convenient,
green
procedure
preparation
3a-methyl-2,3,3a,4-tetrahydropyrrolo[1,2-a]quinazoline-1,5-dione
through
double
cyclocondensation
cascade
using
anthranilamide
ethyl
levulinate.
Screening
various
Brønsted
acid
showed
that
Amberlyst®
15
convenient
choice.
By
applying
mechanochemical
in
N-heterotricyclic
compound
first
time,
it
was
possible
to
shorten
necessary
time
three
hours
compared
24
h
needed
under
conventional
conditions
obtain
high
yield
target
product.
Green Chemistry,
Journal Year:
2021,
Volume and Issue:
23(23), P. 9198 - 9238
Published: Jan. 1, 2021
The
research
progress
on
the
production
of
levulinic
acid
and
its
derivatives
for
fuel
additives
chemicals
from
various
sugars
biomass
feedstocks
have
been
comprehensively
reviewed,
focusing
chemical
processes
mechanisms.
Reaction Chemistry & Engineering,
Journal Year:
2023,
Volume and Issue:
8(8), P. 1969 - 1980
Published: Jan. 1, 2023
Furfural
is
a
versatile,
high-value-added
platform
molecule
that
can
be
produced
from
five
carbon
atom
(C5)
carbohydrates
present
in
lignocellulosic
biomass.
Industrial & Engineering Chemistry Research,
Journal Year:
2023,
Volume and Issue:
62(28), P. 10915 - 10929
Published: July 5, 2023
A
Preyssler-type
heteropolyacid
supported
on
silica,
synthesized
and
characterized
by
FTIR,
was
tested
for
levulinic
acid
(LA)
esterification
with
n-butanol
under
microwave-assisted
batch
reaction
conditions.
The
optimal
conditions
were
found
to
be
40
mg
of
catalyst,
a
5:1
n-butanol/LA
molar
ratio
at
160
°C
3
h,
resulting
in
77%
conversion
100%
selectivity.
catalytic
effect
observed
low
temperatures
(100
°C),
the
microwave
high
(160
°C).
Yield
levulinate
improved
(82%)
CuSO4
as
dehydrating
agent.
kinetic
study
using
pseudohomogeneous
reversible
model
(PH,
EForward
=
31.60
kJ
mol–1
EReverse
11.53
mol–1)
Eley–Rideal
(ER,
E
31.06
provided
best
fitting
experimental
data.
Preyssler-based
catalyst
has
potential
sustainable
synthesis
n-butyl
levulinate,
promising
fuel
additive
can
used
least
five
times
without
loss
activity.
The Journal of Organic Chemistry,
Journal Year:
2022,
Volume and Issue:
87(5), P. 2651 - 2661
Published: Jan. 21, 2022
A
novel
KPF6-promoted
green
method
has
been
developed
for
the
synthesis
of
esters
and
amides.
wide
range
carboxylic
acids
alcohols
or
amines
worked
well
under
reaction
conditions,
thus
providing
good
to
excellent
(61–98%)
yields
corresponding
The
with
bioactive
substrates
such
as
cholesterol,
levulinic
acid,
linoleic
acid.
Wide
substrate
scope,
operational
simplicity,
scalability,
sustainability
make
this
protocol
a
practical
economically
attractive
approach
preparation
ester
Reaction Chemistry & Engineering,
Journal Year:
2023,
Volume and Issue:
8(6), P. 1324 - 1333
Published: Jan. 1, 2023
The
fructose
was
subjected
to
a
dehydration
reaction
produce
5-hydroxymethylfurfural
using
deep
eutectic
solvent
composed
of
choline
chloride,
fructose,
water
as
the
third
component
mixture
and
p
-sulfonic
acid
calix[4]arene
an
organocatalyst.
