Optimization of heterologous production of Bacillus ligniniphilus L1 laccase in Escherichia coli through statistical design of experiments DOI Creative Commons
Ishmael Mutanda,

Zahoor,

Sivasamy Sethupathy

et al.

Microbiological Research, Journal Year: 2023, Volume and Issue: 274, P. 127416 - 127416

Published: June 2, 2023

Language: Английский

Sustainable lignin modifications and processing methods: green chemistry as the way forward DOI
Bram Jacobs, Yawen Yao, Ine Van Nieuwenhove

et al.

Green Chemistry, Journal Year: 2023, Volume and Issue: 25(6), P. 2042 - 2086

Published: Jan. 1, 2023

This review aims to assess the sustainability and greenness of modification processing lignin feedstock using an adaptation CHEM21 Metrics Toolkit includes a guide for green solvents designing ionic liquids.

Language: Английский

Citations

38

Therapeutic strategy of biological macromolecules based natural bioactive compounds of diabetes mellitus and future perspectives: A systematic review DOI Creative Commons
Naiyer Shahzad, Abdullah R. Alzahrani,

Ibrahim Abdel Aziz Ibrahim

et al.

Heliyon, Journal Year: 2024, Volume and Issue: 10(2), P. e24207 - e24207

Published: Jan. 1, 2024

High blood glucose levels are a hallmark of the metabolic syndrome known as diabetes mellitus. More than 600 million people will have by 2045 global prevalence disease continues to rise. Contemporary antidiabetic drugs reduce hyperglycemia and its consequences. However, these come with undesirable side effects, so it's encouraging that research into plant extracts bioactive substances characteristics is on Natural remedies preferable conventional anti-diabetic since they safer for body, more affordable fewer potential adverse effects. Biological macromolecules such liposomes, niosomes, polymeric nanoparticles, solid lipid nanoemulsions metallic nanoparticles explored in this review. Current drug restrictions been addressed, effectiveness plant-based therapies has enhanced merits methods. Plant extracts' loading capacity carriers' stability primary obstacles developing nanocarriers. Hydrophilic, hydrophobic, amphiphilic covered, brief overview amphipathic features phospholipids, nanocarriers provided. Metallic nanoparticles' benefits attendant risks highlighted emphasize their efficiency treating hyperglycemia. Researchers interested loaded therapeutics may find current helpful

Language: Английский

Citations

10

Theoretical insights into the mechanism underlying aflatoxin B1 transformation by the BsCotA-methyl syringate system DOI Creative Commons
Xiaolu Wang,

Lin Cui,

Mengting Liu

et al.

Ecotoxicology and Environmental Safety, Journal Year: 2024, Volume and Issue: 272, P. 116049 - 116049

Published: Feb. 1, 2024

Global concern exists regarding the contamination of food and animal feed with aflatoxin B1 (AFB1), which poses a threat to health both humans animals. Previously, we found that laccase from Bacillus subtilis (BsCotA) effectively detoxified AFB1 in reaction mediated by methyl syringate (MS), although underlying mechanism has not been determined. Therefore, our primary objective this study was explore detoxification employed BsCotA. First, enzyme mediator dependence transformation were studied using BsCotA-MS system, revealed importance MS radical formation during oxidation process. Aflatoxin Q1 (AFQ1) resulting direct BsCotA, identified ultra-high-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS). The results UPLC-MS/MS density functional theory calculations indicated products included AFQ1, AFB1-, AFD1-MS-coupled system. toxicity evaluations substances derived through exhibited markedly reduced compared AFB1. Finally, proposed set different AFB1-transformation pathways generated system based on products. These findings greatly enhance understanding laccase-mediator

Language: Английский

Citations

9

A Comprehensive Review on Mycosynthesis of Nanoparticles, Characteristics, Applications, and Limitations DOI
Abel Kolawole Oyebamiji, Sunday Adewale Akintelu, Samson Olusegun Afolabi

et al.

Plasmonics, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 8, 2025

Language: Английский

Citations

1

Investigating Past, Present, and Future Trends on Interface Between Marine and Medical Research and Development: A Bibliometric Review DOI Creative Commons
Mehdi Zamani, Tetyana Melnychuk, Anton Eisenhauer

et al.

Marine Drugs, Journal Year: 2025, Volume and Issue: 23(1), P. 34 - 34

Published: Jan. 10, 2025

The convergence of marine sciences and medical studies has the potential for substantial advances in healthcare. This study uses bibliometric topic modeling to map progression research themes from 2000 2023, with an emphasis on interdisciplinary subject sciences. Building global publication output at interface between using Hierarchical Dirichlet Process, we discovered dominating topics during three periods, emphasizing shifts focus development trends. Our data show a significant rise output, indicating growing interest bioresources applications. paper identifies two main areas active research, "natural product biochemistry" "trace substance genetics", both great therapeutic potential. We used social network analysis collaborative networks identify prominent scholars institutions driving this progress. indicates important paths policy R&D management operating crossroads healthcare innovation It also underscores significance quantitative foresight methods teams identifying interpreting future scientific convergences breakthroughs.

Language: Английский

Citations

1

Polymerization of proanthocyanidins under the catalysis of miR397a-regulated laccases in Salvia miltiorrhiza and Populus trichocarpa DOI Creative Commons
Caili Li, Xiaoxiao Qiu,

Hou Xue-min

et al.

Nature Communications, Journal Year: 2025, Volume and Issue: 16(1)

Published: Feb. 10, 2025

Language: Английский

Citations

1

A Review of the Biotechnological Potential of Cave Fungi: A Toolbox for the Future DOI Creative Commons
Renan do Nascimento Barbosa, Maria Tamara de Caldas Felipe,

Leticia Francisca Da Silva

et al.

Journal of Fungi, Journal Year: 2025, Volume and Issue: 11(2), P. 145 - 145

Published: Feb. 14, 2025

The study of the intersection between biodiversity and biotechnology has revealed a rich source innovations. Fungi, with their vast range morphologies lifestyles, thrive in various habitats, including caves. With impressive metabolic characteristics, they play key role producing essential biotechnological compounds for economic sectors. This paper aims to consolidate evidence on potential fungi isolated from caves, highlighting urgency conserving exploring these ecosystems. For this purpose, we conducted comprehensive literature search using scientific databases (SciELO, Medline Complete, Medline/PubMed, Web Science, Scopus (Elsevier), Google Scholar). We adopted an interdisciplinary approach by collecting information 22 papers published 2013 2024. Based data, our survey broad potential, antimicrobial compounds, antioxidants, antitumor agents, enzymes, organic acids. emphasize that accurately identifying depositing fungal isolates reference collections are crucial reliable research effective industrial applications, driving bioactivity production substances inhibit pathogens. Conserving protecting cave environment is imperative, considering its continuous discovery contribution advancement.

Language: Английский

Citations

1

Immobilization of Fungal Laccase onto Red Seaweed Biomass as a Novel Support for Efficient Dye Decolorization DOI Creative Commons
Ali Borham,

Mendi Bkhit,

Juanjuan Wang

et al.

Environmental Technology & Innovation, Journal Year: 2025, Volume and Issue: unknown, P. 104143 - 104143

Published: March 1, 2025

Language: Английский

Citations

1

Structural insights, biocatalytic characteristics, and application prospects of lignin-modifying enzymes for sustainable biotechnology DOI Creative Commons

Anil Kumar Singh,

Hafiz M.N. Iqbal, Nunzio Cardullo

et al.

International Journal of Biological Macromolecules, Journal Year: 2023, Volume and Issue: 242, P. 124968 - 124968

Published: May 20, 2023

Lignin modifying enzymes (LMEs) have gained widespread recognition in depolymerization of lignin polymers by oxidative cleavage. LMEs are a robust class biocatalysts that include peroxidase (LiP), manganese (MnP), versatile (VP), laccase (LAC), and dye-decolorizing (DyP). Members the family act on phenolic, non-phenolic substrates been widely researched for valorization lignin, cleavage xenobiotics phenolics. implementation biotechnological industrial sectors has sparked significant attention, although its potential future applications remain underexploited. To understand mechanism sustainable pollution mitigation, several studies undertaken to assess feasibility correlating diverse pollutants binding intermolecular interactions at molecular level. However, further investigation is required fully comprehend underlying mechanism. In this review we presented key structural functional features LMEs, including computational aspects, as well advanced biotechnology research. Furthermore, concluding remarks look ahead, use coupled with framework, built upon artificial intelligence (AI) machine learning (ML), emphasized recent milestone environmental

Language: Английский

Citations

21

Recent Progress and Future Prospects of Laccase Immobilization on MOF Supports for Industrial Applications DOI

Sizhu Ren,

Fangfang Wang, Hui Gao

et al.

Applied Biochemistry and Biotechnology, Journal Year: 2023, Volume and Issue: 196(3), P. 1669 - 1684

Published: June 28, 2023

Language: Английский

Citations

21