Environmental Science & Technology Letters,
Journal Year:
2023,
Volume and Issue:
10(11), P. 983 - 988
Published: March 21, 2023
A
comprehensive
online
database
on
the
toxicity
of
ionic
liquids
(ILs)
is
urgently
needed
to
facilitate
machine
learning
design
environmentally
friendly
ILs.
In
this
direction,
we
present
ILTox,
a
manually
curated
1183
ILs
with
over
6700
pieces
data
across
different
living
organisms,
including
mammalian
cells,
bacteria,
and
plants.
All
values
structural
information
have
been
rigorously
assessed
ensure
quality.
Using
database,
various
models
constructed
quantitatively
analyze
relationship
between
ILs'
structures
their
toxicities.
Furthermore,
optimized
were
used
for
virtual
screening
desired
properties
from
8
million
Our
results
demonstrated
that
ILTox
could
accelerate
transformation
into
critical
structure–toxicity
knowledge.
As
far
as
know,
only
available
IL
now
openly
accessible
at
http://www.iltox.com.
Molecules,
Journal Year:
2025,
Volume and Issue:
30(2), P. 353 - 353
Published: Jan. 16, 2025
Thanks
to
their
unique
physicochemical
properties,
ionic
liquids
(ILs)
have
moved
from
niche
academic
interest
critical
components
in
various
industrial
applications.
The
textile
industry,
facing
significant
environmental
and
economic
pressures,
has
begun
explore
ILs
as
sustainable
alternatives
traditional
solvents
chemicals.
This
review
summarizes
research
on
the
use
of
processes,
including
dyeing,
finishing,
fiber
recycling,
where
high
thermal
stability,
tunable
solubility,
low
volatility
are
exploited
reduce
resource
consumption
impact.
discussion
also
extends
integration
waste
highlighting
innovative
approaches
dissolution
regeneration
aimed
at
circular
economy
goals.
Despite
these
advances,
challenges
such
production
costs
scalability
remain
barriers
widespread
adoption
sector.
Addressing
through
continued
development
is
essential
fully
realize
potential
for
transformation
textiles.
Green Analytical Chemistry,
Journal Year:
2023,
Volume and Issue:
4, P. 100053 - 100053
Published: Feb. 1, 2023
This
review
article
overviews
green
analytical
microextraction
methods
developed
for
food
analysis.
Particular
attention
is
paid
to
the
type
and
characteristics
of
extraction
phase
(solvent
or
sorbent),
given
not
only
their
enormous
impact
on
sustainability
method,
but
also
its
capability
clean-up
efficiency.
Ionic
liquids,
deep
eutectic
solvents,
supramolecular
switchable
solvents
are
among
reviewed,
whereas
polymers,
metal-organic
frameworks,
covalent-organic
carbon-based
nanomaterials
sorbents
discussed.
The
greenness
material
evaluated
in
terms
cost
availability
reagents
employed
preparation,
aspects
synthesis,
possibility
re-use,
safety
and/or
toxicity
related
manipulation.
At
same
time,
main
applications
last
years
field
presented
following
this
vision.
Advanced Functional Materials,
Journal Year:
2024,
Volume and Issue:
34(38)
Published: May 19, 2024
Abstract
Flexible
and
stretchable
ion‐conductive
elastomers
have
shown
promising
applications
in
wearable
flexible
sensor
devices,
biopotential
detection,
electroluminescent
other
areas.
However,
the
currently
employed
gel‐based
materials
encounter
issues
such
as
solvent
volatilization
or
leakage.
Herein,
there
is
an
urgent
requirement
to
develop
a
solid‐state
ionic
conductor
material
that
both
safe
reliable,
free
from
of
liquid
Here,
study
reports
elastomer
with
excellent
mechanical
properties
high
conductivity
based
on
synergistic
strategy
multiple
interaction
forces.
The
ion−conductive
exhibits
(1.42
×
10
−4
S
cm
−1
at
25
°C),
superior
stretchability
(≈1550%
elongation)
strength
(1.48
MPa).
Moreover,
resilience
possesses
self‐healing
ability.
sensor,
prepared
comprehensive
performance,
not
only
demonstrates
strain
sensitivity
but
also
captures
high‐quality
epidermal
signals
human
body
detection.
Additionally,
can
serve
electrode
devices
for
applications.
It
believed
provide
novel
opportunities
advancement
soft
ionotronics.
Acta Pharmaceutica Sinica B,
Journal Year:
2024,
Volume and Issue:
14(11), P. 4683 - 4716
Published: Sept. 2, 2024
About
40%
of
approved
drugs
and
nearly
90%
drug
candidates
are
poorly
water-soluble
drugs.
Low
solubility
reduces
the
drugability.
Effectively
improving
bioavailability
is
a
critical
issue
that
needs
to
be
urgently
addressed
in
development
application.
This
review
briefly
introduces
conventional
solubilization
techniques
such
as
solubilizers,
hydrotropes,
cosolvents,
prodrugs,
salt
modification,
micronization,
cyclodextrin
inclusion,
solid
dispersions,
details
crystallization
strategies,
ionic
liquids,
polymer-based,
lipid-based,
inorganic-based
carriers
bioavailability.
Some
most
commonly
used
carrier
materials
for
presented.
Several
using
summarized.
Furthermore,
this
summarizes
mechanism
each
technique,
reviews
latest
research
advances
challenges,
evaluates
potential
clinical
translation.
could
guide
selection
approach,
dosage
form,
administration
route
Moreover,
we
discuss
several
promising
attracting
increasing
attention
worldwide.
Nature Communications,
Journal Year:
2024,
Volume and Issue:
15(1)
Published: Jan. 24, 2024
Abstract
The
chemical
transformation
of
waste
polymers
into
value-added
chemicals
is
significance
for
circular
economy
and
sustainable
development.
Herein,
we
report
upcycling
poly(succinates)
(PSS)
with
amines
N-substituted
succinimides
over
succinimide
anion-based
ionic
liquids
(ILs,
e.g,
1,8-diazabicyclo[5.4.0]undec-7-ene
succinimide,
[HDBU][Suc]).
Assisted
H
2
O,
[HDBU][Suc])
showed
the
best
performance,
which
could
achieve
complete
a
series
PSS
derivatives
corresponding
diols
under
mild
metal-free
conditions.
Mechanism
investigation
indicates
that
cation-anion
confined
hydrogen-bonding
interactions
among
IL,
ester
group,
amino/amide
groups,
strengthens
nucleophilicity
N
atoms
in
improves
electrophilicity
carbonyl
C
atom
group.
attack
on
group
results
cleavage
C-O
bond
polyester
formation
amide
This
strategy
also
effective
aminolysis
poly(trimethylene
glutarate)
to
glutarimides,
poly(1,4-butylene
adipate)
caprolactone
diimides.
Asian Journal of Pharmaceutical Sciences,
Journal Year:
2024,
Volume and Issue:
19(2), P. 100900 - 100900
Published: March 6, 2024
Ionic
liquids
(ILs)
have
been
proven
to
be
an
effective
technology
for
enhancing
drug
transdermal
absorption.
However,
due
the
unique
structural
components
of
ILs,
design
efficient
ILs
and
elucidation
action
mechanisms
remain
explored.
In
this
review,
basic
principles
ideal
delivery
system
(TDDS)
are
discussed
considering
melting
point,
skin
permeability,
toxicity,
which
depend
on
molar
ratios,
types,
functional
groups
ions
inter-ionic
interactions.
Secondly,
contributions
development
TDDS
through
different
roles
described:
as
novel
penetration
enhancers
absorption
drugs;
solvents
improving
solubility
drugs
in
carriers;
active
pharmaceutical
ingredients
(API-ILs)
regulating
solubility,
release,
pharmacokinetic
behaviors
polymers
smart
medical
materials.
Moreover,
diverse
mechanisms,
mainly
including
interactions
among
drugs,
polymers,
components,
summarized.
Finally,
future
challenges
related
discussed,
underlying
quantitative
structure-activity
relationships,
complex
interaction
forces
between
anions,
microenvironment,
long-term
stability,
vivo
safety
issues.
summary,
article
will
promote
based
ILs.
