Trends in biotechnology, Journal Year: 2023, Volume and Issue: 42(3), P. 369 - 381
Published: Oct. 16, 2023
Language: Английский
Green Chemistry, Journal Year: 2023, Volume and Issue: 25(5), P. 1704 - 1728
Published: Jan. 1, 2023
Publication of the E Factor drew attention to problem waste in chemicals manufacture. Thirty yeas later it is abundantly clear that underlying cause global environmental problems, from climate change plastic pollution.
Language: Английский
Citations
147
Applied Catalysis B Environment and Energy, Journal Year: 2023, Volume and Issue: 330, P. 122622 - 122622
Published: March 13, 2023
Language: Английский
Citations
46
Advances in Colloid and Interface Science, Journal Year: 2023, Volume and Issue: 322, P. 103035 - 103035
Published: Nov. 3, 2023
Surface-functionalized nanostructures are at the forefront of biotechnology, providing new opportunities for biosensors, drug delivery, therapy, and bioimaging applications. The modification significantly impacts performance success various applications by enabling selective precise targeting. This review elucidates widely practiced surface strategies, including click chemistry, cross-coupling, silanization, aldehyde linkers, active ester maleimide epoxy other protein DNA-based methodologies. We also delve into application-focused landscape nano-bio interface, emphasizing four key domains: therapeutics, biosensing, environmental monitoring, point-of-care technologies, highlighting prominent studies. insights presented herein pave way further innovations intersection nanotechnology a useful handbook beginners professionals. draws on sources, latest research articles (2018-2023), to provide comprehensive overview field.
Language: Английский
Citations
44
iScience, Journal Year: 2025, Volume and Issue: 28(2), P. 111763 - 111763
Published: Jan. 7, 2025
Recent years have witnessed tremendous advances in wearable sensors, which play an essential role personalized healthcare for their ability real-time sensing and detection of human health information. Nanozymes, capable mimicking the functions natural enzymes addressing limitations, possess unique advantages such as structural stability, low cost, ease mass production, making them particularly beneficial constructing recognition units biosensors. In this review, we aim to delineate latest advancements nanozymes development biosensors, focusing on key developments nanozyme immobilization strategies, technologies, biomedical applications. The review also highlights current challenges future perspectives. Ultimately, it aims provide insights research endeavors rapidly evolving area.
Language: Английский
Citations
2
Chemical Communications, Journal Year: 2023, Volume and Issue: 59(49), P. 7518 - 7533
Published: Jan. 1, 2023
This review summarises the use of engineered ketoreductases (KREDS), both as whole microbial cells and isolated enzymes, in highly enantiospecific reduction prochiral ketones.
Language: Английский
Citations
29
Chemical Engineering Journal, Journal Year: 2024, Volume and Issue: unknown, P. 158054 - 158054
Published: Nov. 1, 2024
Language: Английский
Citations
14
Catalysis Today, Journal Year: 2024, Volume and Issue: 431, P. 114571 - 114571
Published: Feb. 17, 2024
Language: Английский
Citations
13
Smart Molecules, Journal Year: 2024, Volume and Issue: 2(3)
Published: Aug. 23, 2024
Abstract In situ precise detection of bioactive molecules with high sensitivity and spatiotemporal resolution is essential for studying physiological events disease diagnosis. The utilization versatile fluorescent probes in fluorescence imaging offers a powerful tool vivo biomarkers closely associated pathological conditions. However, the dynamic behavior leading to rapid clearance small molecule from regions interest severely compromises their potential imaging. Notably, self‐immobilizing that selectively recognize diseased tissues while improving retention enrichment enable accurate high‐fidelity this review, we aim summarize strategies employed recent advances performance precision using techniques. Lastly, discuss prospects challenges promote further development application more delicate probes.
Language: Английский
Citations
13
International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 271, P. 132357 - 132357
Published: May 19, 2024
Language: Английский
Citations
12
Angewandte Chemie International Edition, Journal Year: 2024, Volume and Issue: 63(22)
Published: April 1, 2024
Abstract The design and orderly layered co‐immobilization of multiple enzymes on resin particles remain challenging. In this study, the SpyTag/SpyCatcher binding pair was fused to N‐terminus an alcohol dehydrogenase (ADH) aldo‐keto reductase (AKR), respectively. A non‐canonical amino acid (ncAA), p ‐azido‐L‐phenylalanine (p‐AzF), as anchor for covalent bonding enzymes, genetically inserted into preselected sites in AKR ADH. Employing two bioorthogonal counterparts azide–alkyne cycloaddition immobilization ADH enabled sequential dual‐enzyme coating porous microspheres. ordered reactor subsequently used synthesize ( S )‐1‐(2‐chlorophenyl)ethanol asymmetrically from corresponding prochiral ketone, enabling situ regeneration NADPH. exhibited a high catalytic conversion 74 % good reproducibility, retaining 80 its initial activity after six cycles. product had 99.9 ee, which that maintained each cycle. Additionally, double‐layer method significantly increased enzyme loading capacity, approximately 1.7 times greater than traditional single‐layer immobilization. More importantly, it simultaneously both purification carriers, thus providing convenient approach facilitate cascade biocatalysis.
Language: Английский
Citations
9