Advanced Synthesis & Catalysis,
Journal Year:
2022,
Volume and Issue:
364(6), P. 1205 - 1210
Published: Feb. 11, 2022
Abstract
The
oxidative
dehydrogenation
of
N
‐heterocyclic
compounds
by
using
H
2
O
as
oxidant
in
combination
with
polar
solvents
such
1,1,1,3,3,3‐hexafluoroisopropanol
(HFIP)
and
is
described.
Among
these
two
solvents,
the
best
yields
for
heteroaromatic
were
generally
achieved
HFIP.
However,
it
remarkable,
that
use
a
non
toxic
solvent
gave
good
yields.
Furthermore,
procedure
was
implemented
larger‐scale
HFIP
distilled
from
reaction
mixture
reused
(up
to
5
cycles)
without
significant
detriment
outcome.
magnified
image
ChemistrySelect,
Journal Year:
2025,
Volume and Issue:
10(1)
Published: Jan. 1, 2025
Abstract
An
electrochemical
cyclization
strategy
is
employed
herewith
for
the
eco‐friendly
and
cost‐effective
synthesis
of
2‐substituted
quinazolines
by
using
2‐aminobenzylamines
aldehydes
or
alcohols
as
starting
substrates.
The
reactions
were
conducted
under
two
distinct
reaction
temperatures:
25
°C
60
alcohols.
Tetra‐
n
‐butylammonium
iodide
(TBAI)
participates
in
dual
roles
such
as,
an
electrolyte
a
mild
reagent
to
facilitate
formation
at
constant
current
30
mA
graphite
electrode
anode
platinum
cathode
dimethyl
sulfoxide
(DMSO)
solvent.
Under
devised
process,
accomplished
with
broad
substrate
scope
excellent
yields
(up
90%),
which
reduces
toxic
side
products.
plausible
mechanistic
pathways
have
been
formulated,
are
supported
control
experiments
cyclic
voltammetry
studies.
findings
demonstrate
that
conditions,
iodonium
ions
generated,
play
crucial
role
enhancing
efficacy
described
method.
Angewandte Chemie International Edition,
Journal Year:
2023,
Volume and Issue:
62(47)
Published: Oct. 6, 2023
Abstract
Most
attempts
to
synthesize
supramolecular
nanosystems
are
limited
a
single
mechanism,
often
resulting
in
the
formation
of
nanomaterials
that
lack
diversity
properties.
Herein,
hierarchical
assemblies
with
appropriate
variety
fabricated
bulk
via
superstructure‐induced
organic–inorganic
hybrid
strategy.
The
dynamic
balance
between
substructures
and
superstructures
is
managed
using
covalent
organic
frameworks
(COFs)
metal–organic
(MOFs)
as
dual
building
blocks
regulate
performances
assemblies.
Significantly,
from
controlled
cascade
COFs
MOFs
create
highly
active
photocatalytic
systems
through
multiple
topologies.
Our
designed
tandem
photocatalysis
can
precisely
efficiently
conversion
rates
bioactive
molecules
(benzo[d]imidazoles)
competing
redox
pathways.
Furthermore,
benzo[d]imidazoles
catalyzed
by
such
be
isolated
yields
ranging
70
%
93
within
tens
minutes.
multilayered
structural
states
demonstrate
importance
facilitating
propagation
expanding
repertoire
hybrids.
Inorganic Chemistry,
Journal Year:
2022,
Volume and Issue:
61(27), P. 10442 - 10453
Published: June 25, 2022
The
development
of
visible-light
photocatalysts
for
the
selective
oxidative
coupling
amines
to
imines
is
an
area
great
interest.
Herein,
four
hybrid
compounds
based
on
polyoxometalate
anions
and
tris(bipyridine)ruthenium
cations,
Ru(bpy)3[M6O19]
(M
=
Mo,
W)
1-2,
[Ru(bpy)3]2[Mo8O26]
3,
[Ru(bpy)3]2[W10O32]
4,
are
prepared
characterized
by
X-ray
diffraction
(single-crystal
powder),
elemental
analysis,
energy-dispersive
spectroscopy
(EDS)
infrared
(IR)
spectroscopy,
solid
diffuse
reflective
spectroscopy.
Single-crystal
structural
analysis
indicates
that
cations
interact
with
each
other
through
extensive
hydrogen
bonds
in
these
compounds.
These
species
strong
visible-light-harvesting
abilities
suitable
photocatalytic
energy
potentials
show
excellent
activity
selectivity
oxidation
at
room
temperature
air
as
oxidant.
Among
them,
compound
1
[Mo6O19]2-
anion
has
highest
catalytic
activity,
which
can
swiftly
convert
>99.0%
benzylamine
into
N-benzylidenebenzylamine
a
98.0%
25
min
illumination
10
W
445
nm
light-emitting
diode
(LED).
Its
turnover
frequency
reaches
392
h-1,
not
only
better
than
homogeneous
catalyst
[Ru(bpy)3]Cl2
but
also
much
superior
those
achieved
over
most
reported
heterogeneous
catalysts.
Moreover,
it
shows
wide
generality
various
aromatic
amines,
accompanied
advantages
good
recyclability
stability.
mechanism
corresponding
polyoxometalate-based
was
fully
investigated.
Organic & Biomolecular Chemistry,
Journal Year:
2024,
Volume and Issue:
22(6), P. 1157 - 1161
Published: Jan. 1, 2024
Herein,
a
photoinduced
direct
C(sp
2
)–H
alkylation
of
N
-heteroaromatics
by
using
commercially
available
tetrabutylammonium
tribromide
(TBATB)
as
HAT
reagent
is
described.
Molecules,
Journal Year:
2022,
Volume and Issue:
27(2), P. 497 - 497
Published: Jan. 13, 2022
Performing
synthetic
transformation
using
visible
light
as
energy
source,
in
the
presence
of
a
photocatalyst
promoter,
is
currently
high
interest,
and
oxidation
reactions
carried
out
under
these
conditions
oxygen
final
oxidant
are
particularly
convenient
from
an
environmental
point
view.
This
review
summarizes
recent
developments
achieved
oxidative
dehydrogenation
C–N
C–O
bonds,
leading
to
C=N
C=O
respectively,
air
or
pure
metal-free
homogeneous
recyclable
heterogeneous
photocatalysts
irradiation.
The Journal of Organic Chemistry,
Journal Year:
2024,
Volume and Issue:
89(6), P. 4145 - 4155
Published: Feb. 28, 2024
The
environmental
benefits
of
molecular
oxygen
as
the
oxidizing
agent
in
oxidation
reactions
that
synthesize
fine
chemicals
cannot
be
overstated.
Increased
interest
developing
robust
photocatalysts
is
stimulated
by
fact
current
photocatalytic
transformation
boom
has
made
previously
inaccessible
synthetic
approaches
possible.
Motivated
enzymatic
catalysis,
employing
a
reusable
phenalenyl-based
photocatalyst,
we
have
successfully
developed
oxidative
dehydrogenation
utilizing
greener
oxidant.
Under
photoinduced
conditions,
different
types
saturated
N-heterocycles
and
alcohols
were
dehydrogenated.
versatility
this
bioinspired
protocol
demonstrated
wide
variety
N-heteroaromatics,
such
quinoline,
carbazole,
quinoxaline,
acridine,
indole
derivatives,
well
aldehydes
ketones,
synthesized.
Detailed
mechanistic
studies
validate
proposed
mechanism.
Fluorescence
lifetime
CV
experiments
revealed
crucial
role
water
on
efficiency
reaction.
present
also
provides
chemoselectivity
scalability,
leading
to
superior
results
allowing
for
functionalization
bioactive
molecules
at
late
stage
sustainable
manner.