Modulation of 3D Bioprintability in Polysaccharide Bioink by Bioglass Nanoparticles and Multiple Metal Ions for Tissue Engineering DOI
Amitava Bhattacharyya,

Mst Rita Khatun,

S. Narmatha

et al.

Tissue Engineering and Regenerative Medicine, Journal Year: 2023, Volume and Issue: 21(2), P. 261 - 275

Published: Nov. 18, 2023

Language: Английский

Polysaccharide-Based Hydrogels and Their Application as Drug Delivery Systems in Cancer Treatment: A Review DOI Creative Commons
Marco Dattilo, Francesco Patitucci,

Sabrina Prete

et al.

Journal of Functional Biomaterials, Journal Year: 2023, Volume and Issue: 14(2), P. 55 - 55

Published: Jan. 19, 2023

Hydrogels are three-dimensional crosslinked structures with physicochemical properties similar to the extracellular matrix (ECM). By changing hydrogel’s material type, crosslinking, molecular weight, chemical surface, and functionalization, it is possible mimic mechanical of native tissues. currently used in biomedical pharmaceutical fields for drug delivery systems, wound dressings, tissue engineering, contact lenses. Lately, research has been focused on hydrogels from natural sources. Polysaccharides have drawn attention recent years as a promising biological applications, due their biocompatibility, biodegradability, non-toxicity, excellent properties. Polysaccharide-based can be systems efficient release various types cancer therapeutics, enhancing therapeutic efficacy minimizing potential side effects. This review summarizes hydrogels’ classification, properties, synthesis methods. Furthermore, also covers several important polysaccharides (chitosan, alginate, hyaluronic acid, cellulose, carrageenan) widely and, particular, application treatment.

Language: Английский

Citations

85
Mechanical Properties of Alginate Hydrogels Cross-Linked with Multivalent Cations DOI Open Access
Haniyeh Malektaj, Aleksey D. Drozdov, Jesper de Claville Christiansen

et al.

Polymers, Journal Year: 2023, Volume and Issue: 15(14), P. 3012 - 3012

Published: July 12, 2023

Ionically, cross-linked alginate gels have a potential to be used in wide range of biomedical, environmental and catalytic applications. The study deals with preparation hydrogels various cations the analysis their equilibrium swelling mechanical properties. It is shown that type cross-linking process affects elastic moduli degree gels. experimental data small-amplitude oscillatory tests are fitted model involves two material parameters: modulus polymer network measure its inhomogeneity. influence on these quantities studied numerically. revealed dependence ionically differs from predicted by conventional theory for covalently

Language: Английский

Citations

76
Ionotropically-engineered synthesis of mechanically robust hybrid sodium alginate–silica aerogels with enhanced specific surface area for high-capacity and selective dye adsorption from wastewater DOI

Akshay A. Ransing,

Qi Wang, Rushikesh P. Dhavale

et al.

Chemical Engineering Journal, Journal Year: 2025, Volume and Issue: unknown, P. 160590 - 160590

Published: Feb. 1, 2025

Language: Английский

Citations

2
Cellulose-alginate hydrogels and their nanocomposites for water remediation and biomedical applications DOI Creative Commons

Ashvinder K. Rana,

Vijai Kumar Gupta,

Phil Hart

et al.

Environmental Research, Journal Year: 2023, Volume and Issue: 243, P. 117889 - 117889

Published: Dec. 10, 2023

In the last decade, both cellulose and alginate polysaccharides have been extensively utilized for synthesis of biocompatible hydrogels because their alluring characteristics like low cost, biodegradability, hydrophilicity, ease availability non-toxicity. The presence abundant hydrophilic functional groups (like carboxyl hydroxyl) on surface or derivatives makes these materials promising candidates preparation with appealing structures characteristics, leading to growing research in water treatment biomedical fields. These two are typically blended together improve hydrogels' desired qualities (mechanical strength, adsorption properties, cellulose/alginate yield). So, keeping view extensive applicability, present review article, recent advances development cellulose/nanocellulose-alginate-based relevance (adsorption dyes, heavy metals, etc.) field (wound healing, tissue engineering, drug delivery) has reviewed. Further, impact other inorganic/organic additives properties contaminants adsorption, delivery, etc., also studied. Moreover, current difficulties future prospects nanocellulose-alginate-based regarding purification applications discussed at end.

Language: Английский

Citations

30
A Review of Functional Hydrogels for Flexible Chemical Sensors DOI Creative Commons
Pengcheng Zhou, Zongman Zhang, Fan Mo

et al.

Advanced Sensor Research, Journal Year: 2023, Volume and Issue: 3(3)

Published: May 3, 2023

Abstract Hydrogels have drawn considerable attention in the field of flexible chemical sensors due to their unique 3D structure, high permeability, ion‐conductivity, and tissue‐like mechanical properties. These structures properties allow them be functionalized into diverse sensing components respond signals complex environments. Herein, an overview functional hydrogel‐based is provided. First, representative hydrogel materials are introduced operating principles for discussed. Then, state‐of‐the‐art applications highlighted including gas sensors, humidity pH glucose wound monitoring, others. Finally, major challenges opportunities this

Language: Английский

Citations

28
Preparation of alginate coated Pt nanoparticle for radiosensitization of breast cancer tumor DOI
Hamid Rashidzadeh, Farzad Seidi, Mohammadreza Ghaffarlou

et al.

International Journal of Biological Macromolecules, Journal Year: 2023, Volume and Issue: 233, P. 123273 - 123273

Published: Jan. 13, 2023

Language: Английский

Citations

27
Development of a pH-responsive system based on starch and alginate-pectin hydrogels using coaxial 3D food printing DOI

Matthias Dixily R. Lenie,

Safoura Ahmadzadeh, Filip Van Bockstaele

et al.

Food Hydrocolloids, Journal Year: 2024, Volume and Issue: 153, P. 109989 - 109989

Published: March 11, 2024

Language: Английский

Citations

12
Injectable and Multifunctional Hydrogels Based on Poly(N-acryloyl glycinamide) and Alginate Derivatives for Antitumor Drug Delivery DOI
Trung Thang Vu,

Sung‐Han Jo,

Seon-Hwa Kim

et al.

ACS Applied Materials & Interfaces, Journal Year: 2024, Volume and Issue: 16(12), P. 15322 - 15335

Published: March 12, 2024

Chemotherapy is a conventional treatment that uses drugs to kill cancer cells; however, it may induce side effects and be incompletely effective, leading the risk of tumor recurrence. To address this issue, we developed novel injectable thermal/near-infrared (NIR)-responsive hydrogels control drug release. The hydrogel formulation was composed biocompatible alginates, poly(N-acryloyl glycinamide) (PNAGA) copolymers with an upper critical solution temperature, NIR-responsive cross-linkers containing coumarin groups, which were gelated through bioorthogonal inverse electron demand Diels–Alder reactions. exhibited quick gelation times (120–800 s) high loading efficiencies (>90%). demonstrated higher percentage release at 37 °C than 25 due enhanced swelling behavior temperature-responsive PNAGA moieties. Upon NIR irradiation, released most entrapped doxorubicin (DOX) (97%) owing cleavage NIR-sensitive ester groups. displayed biocompatibility normal cells, while induced antitumor activity toward cells. DOX/hydrogels treated light inhibited growth in nude mice bearing tumors. In addition, injected emitted red fluorescence upon excitation green wavelength, so delivery degradation vivo could tracked xenograft model.

Language: Английский

Citations

12
Microfluidics with redox-responsive hydrogels for on-demand BPA degradation DOI Creative Commons
Rok Ambrožič, Ulrich Krühne, Igor Plazl

et al.

Chemical Engineering Journal, Journal Year: 2024, Volume and Issue: 485, P. 149542 - 149542

Published: Feb. 20, 2024

An innovative electrochemical microreactor leveraging redox-responsive hydrogels for the targeted removal of organic pollutants has been presented in this study.The centrepiece is a alginate hydrogel cross-linked with iron ions, capable controlling release Fe ions by an external electrical stimulus.The were used to activate persulfate, leading formation reactive sulfate and hydroxyl radicals situ.The system was tested continuous degradation radical oxidation using bisphenol A (BPA) as model system.This unique, responsive feature enables its modulation thus BPA on demand.In operation, efficiency over 94 % achieved, demonstrating enormous potential microfluidic setup environmental remediation various pollutants.By tailoring process conditions, such residence time, even complete achieved.The robust portable design should enable utilization at site contamination.Due efficient control achieved through design, study further delves into adaptability different matrices showcases promising solution increasing global threat water pollution.Thereby, research opens up new strategies niche-oriented pollution management, including model-based approaches.The CFD applied simulate optimize enabling intensification.

Language: Английский

Citations

11
Green magnetic carbon/alginate biocomposite beads from iron scrap waste for efficient removal of textile dye and heavy metal DOI
Amonrada Saning, Chanchana Thanachayanont,

Ladawan Suksai

et al.

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 261, P. 129765 - 129765

Published: Jan. 29, 2024

Language: Английский

Citations

10