Journal of the American Chemical Society,
Journal Year:
2022,
Volume and Issue:
144(24), P. 10663 - 10687
Published: June 8, 2022
Hydrogen-bonded
organic
frameworks
(HOFs),
self-assembled
from
strategically
pre-designed
molecular
tectons
with
complementary
hydrogen-bonding
patterns,
are
rapidly
evolving
into
a
novel
and
important
class
of
porous
materials.
In
addition
to
their
common
features
shared
other
functionalized
materials
constructed
modular
building
blocks,
the
intrinsically
flexible
reversible
H-bonding
connections
endow
HOFs
straightforward
purification
procedures,
high
crystallinity,
solution
processability,
recyclability.
These
unique
advantages
have
attracted
considerable
attention
across
broad
range
fields,
including
gas
adsorption
separation,
catalysis,
chemical
sensing,
electrical
optical
However,
relatively
weak
interactions
within
can
potentially
limit
stability
potential
use
in
further
applications.
To
that
end,
this
Perspective
highlights
recent
advances
development
chemically
thermally
robust
HOF
systematically
discusses
relevant
design
rules
synthesis
strategies
access
highly
stable
HOFs.
ACS Central Science,
Journal Year:
2022,
Volume and Issue:
8(12), P. 1589 - 1608
Published: Dec. 16, 2022
Hydrogen-bonded
organic
frameworks
(HOFs),
self-assembled
from
or
metalated
building
blocks
(also
termed
as
tectons)
by
hydrogen
bonding,
π–π
stacking,
and
other
intermolecular
interactions,
have
become
an
emerging
class
of
multifunctional
porous
materials.
So
far,
a
library
HOFs
with
high
porosity
has
been
synthesized
based
on
versatile
tectons
supramolecular
synthons.
Benefiting
the
flexibility
reversibility
H-bonds,
feature
structural
flexibility,
mild
synthetic
reaction,
excellent
solution
processability,
facile
healing,
easy
regeneration,
good
recyclability.
However,
flexible
reversible
nature
H-bonds
makes
most
suffer
poor
designability
low
framework
stability.
In
this
Outlook,
we
first
describe
development
features
summarize
design
principles
strategies
to
enhance
their
Second,
highlight
state-of-the-art
for
diverse
applications,
including
gas
storage
separation,
heterogeneous
catalysis,
biological
sensing,
proton
conduction,
applications.
Finally,
current
challenges
future
perspectives
are
discussed.
Journal of the American Chemical Society,
Journal Year:
2024,
Volume and Issue:
146(6), P. 3567 - 3584
Published: Feb. 1, 2024
Covalent
organic
frameworks
(COFs)
are
an
emerging
class
of
highly
porous
crystalline
polymers
comprised
entirely
linkers
connected
by
strong
covalent
bonds.
Due
to
their
excellent
physicochemical
properties
(e.g.,
ordered
structure,
porosity,
and
stability),
COFs
considered
ideal
materials
for
developing
state-of-the-art
separation
membranes.
In
fact,
significant
advances
have
been
made
in
the
last
six
years
regarding
fabrication
functionalization
COF
particular,
utilized
obtain
thin-film,
composite,
mixed
matrix
membranes
that
could
achieve
effective
rejection
(mostly
above
80%)
dyes
model
foulants
humic
acid).
COF-based
membranes,
especially
those
prepared
embedding
into
polyamide
thin-films,
obtained
adequate
salts
desalination
applications.
However,
claims
structure
mechanisms
remain
unclear
debatable.
this
perspective,
we
analyze
critically
design
exploitation
membrane
performance
water
treatment
addition,
technological
challenges
associated
with
properties,
methods,
efficacy
highlighted
redirect
future
research
efforts
realizing
selective
scale-up
industrial
Chemical Society Reviews,
Journal Year:
2023,
Volume and Issue:
52(21), P. 7504 - 7523
Published: Jan. 1, 2023
Hydrogen-bonded
organic
frameworks
(HOFs)
are
an
emerging
attractive
class
of
highly
crystalline
porous
materials
characterized
by
significant
biocompatibility,
rich
chemical
functionalities
and
well-defined
porosity.
The
unique
advantages
including
metal-free
nature
reversible
binding
manner
significantly
distinguish
HOFs
from
other
in
the
biotechnology
biomedical
field.
However,
relevant
HOF
studies
still
remain
their
infancy
despite
promising
remarkable
results
that
have
been
presented
recent
years.
Due
to
intricate
dynamic
physiological
conditions,
major
challenge
lies
stability
structural
diversity
vivo.
In
this
Tutorial
Review,
we
summarize
common
building
blocks
for
construction
HOF-based
functional
biomaterials
latest
developments
biological
Moreover,
highlight
current
challenges
regarding
functionalization
along
with
corresponding
potential
solutions.
This
Review
will
a
profound
effect
future
years
on
design
applications
biomaterials.
Nature,
Journal Year:
2024,
Volume and Issue:
630(8015), P. 102 - 108
Published: May 22, 2024
Abstract
Metal–organic
frameworks
(MOFs)
are
useful
synthetic
materials
that
built
by
the
programmed
assembly
of
metal
nodes
and
organic
linkers
1
.
The
success
MOFs
results
from
isoreticular
principle
2
,
which
allows
families
structurally
analogous
to
be
in
a
predictable
way.
This
relies
on
directional
coordinate
covalent
bonding
define
framework
geometry.
However,
strategies
do
not
translate
other
common
crystalline
solids,
such
as
salts
3–5
intermolecular
ionic
is
less
directional.
Here
we
show
chemical
knowledge
can
combined
with
computational
crystal-structure
prediction
6
(CSP)
design
porous
ammonium
halide
contain
no
metals.
these
salt
tightly
packed
clusters
direct
crystallize
specific
ways,
demonstrated
presence
well-defined
spikes
low-energy,
low-density
structures
predicted
lattice
energy
landscapes
7,8
These
allow
us
select
combinations
cations
anions
will
form
thermodynamically
stable,
channel
sizes,
functionalities
geometries
priori.
Some
adsorb
molecular
guests
iodine
quantities
exceed
those
most
MOFs,
this
could
for
applications
radio-iodine
capture
9–12
More
generally,
synthesis
scalable,
involving
simple
acid–base
neutralization,
strategy
makes
it
possible
create
family
non-metal
combine
high
charge
density
permanent
porosity.
Materials Today Sustainability,
Journal Year:
2024,
Volume and Issue:
25, P. 100672 - 100672
Published: Jan. 13, 2024
Mixed-matrix
membranes
(MMMs)
have
emerged
as
a
promising
approach
for
developing
new,
stable,
and
highly
effective
gas
liquid
separation
materials.
MMMs
combine
porous
crystalline
framework
materials,
such
Metal-organic
frameworks
(MOFs),
covalent
organic
(COFs),
hydrogen-bonded
(HOFs),
fillers
incorporated
in
polymer
matrix.
This
article
comprehensively
reviews
MMM
research,
discussing
the
structure
properties
of
MOFs,
COFs,
HOFs
their
attractiveness
use
MMMs.
The
also
mixed
matrix
filtration
with
various
water
treatment
applications.
potential
meeting
needs
different
industries
is
demonstrated
through
discussion
specific
examples.
Overall,
this
highlights
significant
technology
next-generation
materials
attempts
to
cover
most
recent
progress
design
deployment
COFs
HOFs-based
MMMs,
are
remaining
obstacles
prospects.
work
enormous
these
applications
raises
attention
toward
economic
aspect
market
diffusion
Chemistry - A European Journal,
Journal Year:
2024,
Volume and Issue:
30(17)
Published: Jan. 5, 2024
Abstract
Hydrogen‐bonded
organic
frameworks
(HOFs)
are
a
class
of
crystalline
framework
materials
assembled
by
hydrogen
bonds.
HOFs
have
the
advantages
high
crystallinity,
mild
reaction
conditions,
good
solution
processability,
and
reproducibility.
Coupled
with
reversibility
flexibility
bonds,
can
be
into
wide
diversity
structures.
Since
bonding
energy
bonds
is
lower
than
that
ligand
covalent
prone
to
collapse
after
desolventisation
stability
not
high,
which
limits
development
application
HOFs.
In
recent
years,
numerous
stable
functional
been
developed
π–π
stacking,
highly
interpenetrated
networks,
charge‐assisted,
ligand‐bond‐assisted,
molecular
weaving,
cross‐linking.
Charge‐assisted
ionic
introduce
electrostatic
attraction
improve
while
enriching
structural
functionality.
this
paper,
we
review
development,
principles
rational
design
assembly
charge‐assisted
HOFs,
introduces
different
building
block
construction
modes
Highlight
applications
in
gas
adsorption
separation,
proton
conduction,
biological
applications,
etc.,
prospects
for
diverse
structures
multifunctional
applications.
Advanced Science,
Journal Year:
2024,
Volume and Issue:
11(22)
Published: April 22, 2024
Abstract
Hydrogen‐bonded
organic
frameworks
(HOFs)
are
emerging
porous
materials
that
show
high
structural
flexibility,
mild
synthetic
conditions,
good
solution
processability,
easy
healing
and
regeneration,
recyclability.
Although
these
properties
give
them
many
potential
multifunctional
applications,
their
unstable
due
to
the
presence
of
only
weak
reversible
hydrogen
bonds.
In
this
work,
development
history
synthesis
methods
HOFs
reviewed,
categorize
design
concepts
strategies
improve
stability.
More
importantly,
significant
latest
HOF‐related
research
for
addressing
energy
environmental
issues,
work
discusses
advances
in
storage
conversion,
substance
generation
isolation,
detection
degradation
transformation,
biological
applications.
Furthermore,
a
discussion
coupling
orientation
HOF
cross‐cutting
fields
environment
is
presented
first
time.
Finally,
current
challenges,
opportunities,
advance
applications
discussed.
Chemical Society Reviews,
Journal Year:
2024,
Volume and Issue:
53(8), P. 3640 - 3655
Published: Jan. 1, 2024
This
tutorial
review
discusses
the
design
principles,
implications,
and
future
challenges
associated
with
peptide-based
hydrogen-bonded
porous
frameworks
(P-HPFs).
Aggregate,
Journal Year:
2024,
Volume and Issue:
5(2)
Published: Jan. 4, 2024
Abstract
The
development
of
efficient
drug
delivery
systems
is
essential
for
improving
the
efficacy
and
safety
cancer
drugs,
particularly
aggressive
difficult‐to‐treat
cancers.
Covalent
organic
frameworks
(COFs)
are
emerging
as
innovative
porous
nanomaterials
in
(DDS),
due
to
their
unique
properties,
including
metal‐free
skeleton,
predetermined
structures
pore
geometries,
high
porosity,
large
surface
area,
facile
modification
potential,
good
biocompatibility.
These
characteristics
make
COFs
excellent
candidates
by
enhancing
loading
capacity
enabling
precise
encapsulation.
This
review
emphasizes
importance
donor‐acceptor‐based
COFs,
which
provide
channels
charge
transportation,
we
also
explore
how
π‐conjugated
skeleton
enhances
its
long‐acting
fluorescent
properties
facilitates
uptake
via
cell
endocytosis.
While
this
primarily
focuses
on
recent
advancements
COF‐based
targeted
DDS,
it
acknowledges
challenges
posed
diverse
geometries
materials
discusses
potential
solutions.
Further,
underlines
developing
future
carriers
that
can
successfully
specifically
target
cells,
treatment
efficiency
while
reducing
adverse
side
effects.
