Current state of the art and future directions for implantable sensors in medical technology: Clinical needs and engineering challenges DOI Creative Commons
David Yogev, Tomer Goldberg, Amir Arami

et al.

APL Bioengineering, Journal Year: 2023, Volume and Issue: 7(3)

Published: Sept. 1, 2023

Implantable sensors have revolutionized the way we monitor biophysical and biochemical parameters by enabling real-time closed-loop intervention or therapy. These technologies align with new era of healthcare known as 5.0, which encompasses smart disease control detection, virtual care, intelligent health management, monitoring, decision-making. This review explores diverse biomedical applications implantable temperature, mechanical, electrophysiological, optical, electrochemical sensors. We delve into engineering principles that serve foundation for their development. also address challenges faced researchers designers in bridging gap between sensor research clinical adoption emphasizing importance careful consideration requirements challenges. highlight need future to explore issues such long-term performance, biocompatibility, power sources, well potential transform across multiple disciplines. It is evident immense field medical technology. However, remains wide, there are still major obstacles overcome before they can become a widely adopted part practice.

Language: Английский

Strategies for body-conformable electronics DOI Creative Commons
Siyi Liu, Yifan Rao, Hongwoo Jang

et al.

Matter, Journal Year: 2022, Volume and Issue: 5(4), P. 1104 - 1136

Published: April 1, 2022

Language: Английский

Citations

186

A review of etching methods of MXene and applications of MXene conductive hydrogels DOI
Can Zhou, Xiaohan Zhao, Yingshuo Xiong

et al.

European Polymer Journal, Journal Year: 2022, Volume and Issue: 167, P. 111063 - 111063

Published: Feb. 8, 2022

Language: Английский

Citations

182

Functional Hydrogels for Treatment of Chronic Wounds DOI Creative Commons

Ilayda Firlar,

Mine Altunbek,

Colleen McCarthy

et al.

Gels, Journal Year: 2022, Volume and Issue: 8(2), P. 127 - 127

Published: Feb. 17, 2022

Chronic wounds severely affect 1-2% of the population in developed countries. It has been reported that nearly 6.5 million people United States suffer from at least one chronic wound their lifetime. The treatment is critical for maintaining physical and mental well-being patients improving quality life. There are a host methods wounds, including debridement, hyperbaric oxygen therapy, ultrasound, electromagnetic therapies, negative pressure skin grafts, hydrogel dressings. Among these, dressings represent promising viable choice because tunable functional properties, such as biodegradability, adhesivity, antimicrobial, anti-inflammatory, pre-angiogenic bioactivities, can accelerate healing wounds. This review summarizes types phases process, key therapeutic approaches. Hydrogel-based reviewed multifunctional properties advantages Examples commercially available also provided to demonstrate effectiveness over other healing.

Language: Английский

Citations

141

Hydrogels for underwater adhesion: adhesion mechanism, design strategies and applications DOI
Xintao Ma, Xun Zhou, Junjie Ding

et al.

Journal of Materials Chemistry A, Journal Year: 2022, Volume and Issue: 10(22), P. 11823 - 11853

Published: Jan. 1, 2022

This review summarizes the adhesion mechanism and design strategies of underwater hydrogels, generalizes their application fields (adhesives, motion monitoring, marine environmental exploration coatings).

Language: Английский

Citations

141

Recent Advances in Mucoadhesive Interface Materials, Mucoadhesion Characterization, and Technologies DOI
Ilker S. Bayer

Advanced Materials Interfaces, Journal Year: 2022, Volume and Issue: 9(18)

Published: May 23, 2022

Abstract Mucoadhesion is an extremely important field of adhesion science and the comprehensive understanding modulation mucoadhesion can lead to lifesaving materials technologies. For instance, deadly cases COVID‐19 (SARS‐CoV‐2) cytokine storm are associated with viral overproduction mucus, which obstructs airways. Mucin key polymeric compound that known as a family high molecular weight, heavily glycosylated proteins in epithelial tissues. occur many different ways such receptor specific charge interactions, covalent or noncovalent bonds. New mucin‐mimic polymers replicate its beneficial traits prevent biofilm formation biofouling not only biotechnology but also membrane This review addresses latest understandings related mucin's role wet considering physiological conditions shows how this translates into interfacial polymer adhesion. Advances measurement techniques including rheological aspects polymer–mucin adhesive interactions presented. Specific mucoadhesive systems discussed hydrogel mucoadhesion, catechol/dopamine functionalization, nanoparticles. overview may expand current between soft contributes elastocapillary phenomena design applications new membranes, drugs, pharmaceutical devices, lubricated surfaces.

Language: Английский

Citations

87

Injectable multifunctional hyaluronic acid/methylcellulose hydrogels for chronic wounds repairing DOI
Linyu Long, Cheng Hu, Wenqi Liu

et al.

Carbohydrate Polymers, Journal Year: 2022, Volume and Issue: 289, P. 119456 - 119456

Published: April 4, 2022

Language: Английский

Citations

74

Gel-based strain/pressure sensors for underwater sensing: Sensing mechanisms, design strategies and applications DOI
Xun Zhou, Xiaohan Zhao, Yanyan Wang

et al.

Composites Part B Engineering, Journal Year: 2023, Volume and Issue: 255, P. 110631 - 110631

Published: Feb. 21, 2023

Language: Английский

Citations

67

Liquid Metal Patterning and Unique Properties for Next‐Generation Soft Electronics DOI Creative Commons
Minwoo Kim, Hyungjun Lim, Seung Hwan Ko

et al.

Advanced Science, Journal Year: 2023, Volume and Issue: 10(6)

Published: Jan. 15, 2023

Room-temperature liquid metal (LM)-based electronics is expected to bring advancements in future soft owing its conductivity, conformability, stretchability, and biocompatibility. However, various difficulties arise when patterning LM because of rheological features such as fluidity surface tension. Numerous attempts are made overcome these difficulties, resulting LM-patterning methods. An appropriate choice method based on comprehensive understanding necessary fully utilize the unique properties. Therefore, authors aim provide thorough knowledge about methods properties for LM-based electronics. First, essential considerations investigated. Then, methods-serial-patterning, parallel-patterning, intermetallic bond-assisted patterning, molding/microfluidic injection-are categorized Finally, perspectives with provided. They include outstanding biocompatibility, permeability, restorability, recyclability. Also, they areas radio frequency electronics, robots, heterogeneous catalyst. devices permeate daily lives if aforementioned analyzed utilized.

Language: Английский

Citations

66

Carbon Dot‐Based Hydrogels: Preparations, Properties, and Applications DOI
Yijie Wang,

Tingjie Lv,

Keyang Yin

et al.

Small, Journal Year: 2023, Volume and Issue: 19(17)

Published: Jan. 29, 2023

Hydrogels have extremely high moisture content, which makes it very soft and excellently biocompatible. They become an important material a wide range of applications in various fields such as biomedicine, bionic smart material, electrochemistry. Carbon dot (CD)-based hydrogels are based on carbon dots (CDs) auxiliary substances, forming gel with comprehensive properties individual components. CDs embedding could not only solve their aggregation-caused quenching (ACQ) effect, but also manipulate the even bring some novel properties, achieving win-win situation. In this review, preparation methods, formation mechanism, CD-based hydrogels, sensing, adsorption, energy storage, catalysis -are summarized. Finally, brief discussion future research directions will be given.

Language: Английский

Citations

66

Enhanced Strength for Double Network Hydrogel Adhesive Through Cohesion‐Adhesion Balance DOI Creative Commons
Rijian Song, Xiaoyu Wang, Melissa Johnson

et al.

Advanced Functional Materials, Journal Year: 2024, Volume and Issue: 34(23)

Published: Feb. 15, 2024

Abstract Hydrogel adhesives exhibit great potential in various biomedical fields such as tissue sealing and soft robotics. However, the high‐water content defective network structures of these hydrogel result low intrinsic mechanical strength, severely impeding their application. In this study, it is reported that strong adhesive strength can be achieved when a balance established between forces cohesive forces. Based on principle, new double (DN) design created to combine an polyvinyl alcohol (PVA) first with flexible sodium alginate (SA) second network. A delicate cohesion adhesion by adjusting ratio rigid As result, balanced DN exhibits approximately three times higher than non‐balance situation.

Language: Английский

Citations

58