Highly Selective Cyclization and Isomerization of Propargylamines to Access Functionalized Quinolines and 1-Azadienes DOI Creative Commons
Zheng‐Guang Wu, Hui Zhang, Chenhui Cao

et al.

Molecules, Journal Year: 2023, Volume and Issue: 28(17), P. 6259 - 6259

Published: Aug. 26, 2023

Developing new organic reactions with excellent atom economy and high selectivity is significant urgent. Herein, by ingeniously regulating the reaction conditions, highly selective transformations of propargylamines have been successfully implemented. The palladium-catalyzed cyclization generates a series functionalized quinoline heterocycles, while base-promoted isomerization affords diverse 1-azadienes. Both good functional group tolerance, mild yields up to 93%. More importantly, these heterocycles 1-azadienes could be flexibly transformed into valuable compounds, illustrating validity practicability propargylamine-based reactions.

Language: Английский

Copper–cobalt coordination polymers and catalytic applications on borrowing hydrogen reactions DOI

Shaoze Chang,

Hongqiang Liu, Gang Shi

et al.

New Journal of Chemistry, Journal Year: 2022, Volume and Issue: 46(33), P. 15929 - 15936

Published: Jan. 1, 2022

A porous copper–cobalt polymer was synthesized and achieved applications for the N-alkylation of sulfonamides with alcohols, carboxamides alcohols.

Language: Английский

Citations

5
An efficient approach for 3-haloquinoline synthesis: PhI(OAc)2-mediated A3-X type tandem annulation of amine, aldehyde, alkyne and halide salt DOI
Hongbin Lu,

Yuchen Qiu,

Qin Zhao

et al.

Tetrahedron Letters, Journal Year: 2022, Volume and Issue: 101, P. 153927 - 153927

Published: June 7, 2022

Language: Английский

Citations

4
Deoxygenative Cross-coupling of Aryl Ketones with (Hetero)arenes Mediated by a TiCl4/Ammonia Borane System DOI
Yongjun Zang, Shijie Zhou, Qian Chen

et al.

Tetrahedron, Journal Year: 2024, Volume and Issue: 163, P. 134147 - 134147

Published: Aug. 1, 2024

Language: Английский

Citations

0
Utilizing Nitroarenes and HCHO to Directly Construct Functional N‐Heterocycles by Supported Cobalt/Amino Acid Relay Catalysis DOI
Jialu Sun, Chenggang Ci, Huanfeng Jiang

et al.

Angewandte Chemie, Journal Year: 2023, Volume and Issue: 135(22)

Published: March 22, 2023

Abstract Due to the generation of multiple intermediates during nitroarene reduction, precise interception single one develop tandem reactions involving both C−C and C−N bond formations still remains a significant challenge. Herein, relay catalysis supported bifunctional cobalt catalyst with l ‐proline has been successfully applied establish bran‐new reductive annulation reaction nitroarenes formaldehyde, which enables direct diverse construction symmetrical unsymmetrical 1,3‐diaryl imidazolines. It proceeds operational simplicity, good substrate functionality compatibility, excellent step atom‐efficiency. Mechanistic studies reveal that Co‐catalyst exhibits synergistic effect on formation key N ‐hydroxy imine, subsequently facilitates formation. The current work opens door useful transformations by reduction‐interrupted strategy.

Language: Английский

Citations

1
Highly Selective Cyclization and Isomerization of Propargylamines to Access Functionalized Quinolines and 1-Azadienes DOI Creative Commons
Zheng‐Guang Wu, Hui Zhang, Chenhui Cao

et al.

Molecules, Journal Year: 2023, Volume and Issue: 28(17), P. 6259 - 6259

Published: Aug. 26, 2023

Developing new organic reactions with excellent atom economy and high selectivity is significant urgent. Herein, by ingeniously regulating the reaction conditions, highly selective transformations of propargylamines have been successfully implemented. The palladium-catalyzed cyclization generates a series functionalized quinoline heterocycles, while base-promoted isomerization affords diverse 1-azadienes. Both good functional group tolerance, mild yields up to 93%. More importantly, these heterocycles 1-azadienes could be flexibly transformed into valuable compounds, illustrating validity practicability propargylamine-based reactions.

Language: Английский

Citations

1