Trends in Food Science & Technology,
Journal Year:
2023,
Volume and Issue:
138, P. 323 - 338
Published: June 21, 2023
Metal-Organic
Frameworks
(MOFs),
a
relatively
new
category
of
materials
which
came
into
attention
about
two
decades
ago,
have
caught
researchers
across
industrial
sectors
including
food
additives,
flavor,
packaging
and
sensing.
More
than
100,000
such
structures
been
synthesized,
approximately
500,000
theoretically
determined.
However,
most
these
are
synthesized
using
transition
metal
ions
petroleum
derived
ligands
creates
cytotoxicity
sustainability
related
concerns,
respectively.
Additional
challenges
with
MOFs
include
thermal,
moisture,
hydrothermal
stability
as
well
pH
sensitivity,
reusability
scalability.
To
mitigate
the
environmental,
toxicological
utilized
bio-compatible
edible
linkers
polyphenols,
cyclodextrins,
peptides,
amino
acids
etc.
linked
non-toxic
cations
endogenous/intercellular
Zn2+,
Fe2+,
Fe3+
Mg2+,
Ca2+,
K+
among
others.
Other
factors
hinder
real-life
applications
thermal
or
stability,
application
medium,
food-contact
concerns.
This
paper
systematically
provides
an
overview
various
coordination
ability,
acid
dissociation
constant
bond
orbitals
others
links
them
to
reusability.
Various
made
from
edible,
biocompatible,
biological
endogenous
suitable
for
food,
contact
identified.
Structure,
porosity
physical
properties
MOF
families
summarized.
Pharmaceutics,
Journal Year:
2022,
Volume and Issue:
14(2), P. 254 - 254
Published: Jan. 21, 2022
Doxorubicin
(DOX)
is
one
of
the
most
widely
used
anthracycline
anticancer
drugs
due
to
its
high
efficacy
and
evident
antitumoral
activity
on
several
cancer
types.
However,
effective
utilization
hindered
by
adverse
side
effects
associated
with
administration,
detriment
patients’
quality
life,
general
toxicity
healthy
fast-dividing
cells.
Thus,
delivering
DOX
tumor
site
encapsulated
inside
nanocarrier-based
systems
an
area
research
that
has
garnered
colossal
interest
in
targeted
medicine.
Nanoparticles
can
be
as
vehicles
for
localized
delivery
release
DOX,
decreasing
neighboring
cells
providing
more
control
over
drug’s
distribution.
This
review
presents
overview
DOX-based
nanocarrier
systems,
covering
loading
methods,
rate,
cytotoxicity
liposomal,
micellar,
metal
organic
frameworks
(MOFs)
platforms.
Biomaterials Science,
Journal Year:
2023,
Volume and Issue:
11(8), P. 2661 - 2677
Published: Jan. 1, 2023
MOF-hydrogel
composites
are
an
emerging
class
of
composite
materials
with
many
potential
biomedical
applications.
In
this
review
article,
we
discuss
the
state-of-the-art
and
prospects
for
future
development.
Pharmaceutics,
Journal Year:
2023,
Volume and Issue:
15(3), P. 931 - 931
Published: March 13, 2023
Cancer
is
a
multifaceted
disease
that
results
from
the
complex
interaction
between
genetic
and
environmental
factors.
mortal
with
biggest
clinical,
societal,
economic
burden.
Research
on
better
methods
of
detection,
diagnosis,
treatment
cancer
crucial.
Recent
advancements
in
material
science
have
led
to
development
metal–organic
frameworks,
also
known
as
MOFs.
MOFs
recently
been
established
promising
adaptable
delivery
platforms
target
vehicles
for
therapy.
These
constructed
fashion
offers
them
capability
drug
release
stimuli-responsive.
This
feature
has
potential
be
exploited
therapy
externally
led.
review
presents
an
in-depth
summary
research
conducted
date
field
MOF-based
nanoplatforms
therapeutics.
Nanoscale Advances,
Journal Year:
2024,
Volume and Issue:
6(7), P. 1800 - 1821
Published: Jan. 1, 2024
Here,
we
explored
the
recent
development
of
MOF-based
nanomaterials
for
biomedical
applications.
not
only
show
excellent
bio-imaging
and
biosensing
performance
but
also
can
be
well
designed
as
bio-carriers
in
drug
delivery.
Small,
Journal Year:
2024,
Volume and Issue:
20(30)
Published: March 7, 2024
Abstract
In
recent
years,
there
has
been
growing
interest
in
developing
innovative
materials
and
therapeutic
strategies
to
enhance
wound
healing
outcomes,
especially
for
chronic
wounds
antimicrobial
resistance.
Metal–organic
frameworks
(MOFs)
represent
a
promising
class
of
next‐generation
dressings.
Their
high
surface
area,
pore
structures,
stimuli‐responsiveness,
antibacterial
properties,
biocompatibility,
potential
combination
therapies
make
them
suitable
complex
care
challenges.
MOF‐based
composites
promote
cell
proliferation,
angiogenesis,
matrix
synthesis,
acting
as
carriers
bioactive
molecules
promoting
tissue
regeneration.
They
also
have
stimuli‐responsivity,
enabling
photothermal
skin
cancer
infections.
Herein,
critical
analysis
the
current
state
research
on
MOFs
dressings
is
provided,
offering
valuable
insights
into
applications,
challenges,
future
directions
this
field.
This
literature
review
targeted
multifunctionality
nature
wound‐disease
therapy
from
different
aspects
discussed
most
advancements
made
context,
reader
will
find
how
contributed
field
yield
more
effective,
functional,
they
lead
next
generation
biomaterials
