Journal of Colloid and Interface Science, Journal Year: 2025, Volume and Issue: 684, P. 647 - 657
Published: Jan. 8, 2025
Language: Английский
The Science of The Total Environment, Journal Year: 2023, Volume and Issue: 902, P. 165944 - 165944
Published: Aug. 4, 2023
Language: Английский
Citations
114
Acta Pharmaceutica Sinica B, Journal Year: 2023, Volume and Issue: 13(11), P. 4391 - 4416
Published: May 20, 2023
Owing to the inherent shortcomings of traditional therapeutic drugs in terms inadequate efficacy and toxicity clinical treatment, nanomedicine designs have received widespread attention with significantly improved reduced non-target side effects. Nanomedicines hold tremendous theranostic potential for treating, monitoring, diagnosing, controlling various diseases are attracting an unfathomable amount input research resources. Against backdrop exponentially growing number publications, it is imperative help audience get a panorama image activities field nanomedicines. Herein, this review elaborates on development trends nanomedicines, emerging nanocarriers, vivo fate safety their extensive applications. Moreover, challenges obstacles hindering translation nanomedicines also discussed. The elaboration aspects may enlighten readers set route future endeavors.
Language: Английский
Citations
82
Chemical Society Reviews, Journal Year: 2024, Volume and Issue: 53(11), P. 5626 - 5676
Published: Jan. 1, 2024
Metalation of metal-organic frameworks (MOFs) has been developed as a prominent strategy for materials functionalization pore chemistry modulation and property optimization. By introducing exotic metal ions/complexes/nanoparticles onto/into the parent framework, many metallized MOFs have exhibited significantly improved performance in wide range applications. In this review, we focus on research progress metalation during last five years, spanning design principles, synthetic strategies, potential Based crystal engineering minor change MOF composition through would lead to leveraged variation properties. This review starts from general strategies established incorporation species within MOFs, followed by principles graft desired functionality while maintaining porosity frameworks. Facile contributed great number bespoke with excellent performance, summarize their applications gas adsorption separation, heterogeneous catalysis, detection sensing, energy storage conversion. The underlying mechanisms are also investigated state-of-the-art techniques analyzed gaining insight into structure-property relationships, which turn facilitate further development principles. Finally, current challenges opportunities discussed, promising future directions customizing next-generation advanced outlined well.
Language: Английский
Citations
54
Journal of Hazardous Materials, Journal Year: 2023, Volume and Issue: 447, P. 130848 - 130848
Published: Jan. 21, 2023
Language: Английский
Citations
53
Advances in Colloid and Interface Science, Journal Year: 2023, Volume and Issue: 313, P. 102865 - 102865
Published: Feb. 27, 2023
Language: Английский
Citations
48
Nature Reviews Methods Primers, Journal Year: 2024, Volume and Issue: 4(1)
Published: June 27, 2024
Language: Английский
Citations
48
Advanced Science, Journal Year: 2023, Volume and Issue: 10(10)
Published: Feb. 5, 2023
Due to radiation resistance and the immunosuppressive microenvironment of metastatic osteosarcoma, novel radiosensitizers that can sensitize radiotherapy (RT) antitumor immunity synchronously urgently needed. Here, authors developed a nanoscale metal-organic framework (MOF, named TZM) by co-doping high-atomic elements Ta Zr as metal nodes porphyrinic molecules (tetrakis(4-carboxyphenyl)porphyrin (TCPP)) photosensitizing ligand. Given 3D arrays ultra-small heavy metals, porous TZM serves an efficient attenuator absorbing X-ray energy sensitizing hydroxyl radical generation for RT. Ta-Zr narrowed highest occupied molecular orbital-lowest unoccupied orbital (HOMO-LUMO) gap exhibited close levels between singlet triplet photoexcited states, facilitating transfer photosensitizer TCPP oxygen (
Language: Английский
Citations
47
Food Chemistry, Journal Year: 2023, Volume and Issue: 413, P. 135640 - 135640
Published: Feb. 4, 2023
Language: Английский
Citations
44
Biomaterials Research, Journal Year: 2023, Volume and Issue: 27(1)
Published: Feb. 9, 2023
The immune system interacts with cancer cells in various intricate ways that can protect the individual from overproliferation of cells; however, these interactions also lead to malignancy. There has been a dramatic increase application immunotherapy last decade. However, low immunogenicity, poor specificity, weak presentation efficiency, and off-target side effects still limit its widespread application. Fortunately, advanced biomaterials effectively contribute play an important role treatment, making it research hotspot biomedical field. This review discusses immunotherapies development related for first summarizes types tumor applicable clinical practice as well their underlying mechanisms. Further, focuses on applied metal nanomaterials, silicon nanoparticles, carbon nanotubes, polymer cell membrane nanocarriers. Moreover, we introduce preparation processing technologies (liposomes, microspheres, microneedles, hydrogels) summarize mechanisms when immunotherapy. Finally, discuss future advancements shortcomings Research biomaterial-based is booming; several challenges remain be overcome transition experimental Biomaterials have optimized continuously nanotechnology achieved continuous progression, ensuring more efficient biomaterials, thereby providing platform opportunity breakthroughs
Language: Английский
Citations
43
Coordination Chemistry Reviews, Journal Year: 2023, Volume and Issue: 497, P. 215434 - 215434
Published: Sept. 17, 2023
Language: Английский
Citations
43