Exploring the potential of hydroxyapatite-based materials in biomedicine: A comprehensive review

Materials Science and Engineering R Reports, Journal Year: 2024, Volume and Issue: 161, P. 100870 - 100870

Published: Nov. 2, 2024

Language: Английский

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A Fish-Gill-Inspired Biomimetic Multiscale-Ordered Hydrogel-Based Solar Water Evaporator for Highly Efficient Salt-Rejecting Seawater Desalination

ACS Applied Materials & Interfaces, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 23, 2025

Solar energy-driven steam generation is a renewable, energy-efficient technology that can alleviate the global clean water shortage through seawater desalination. However, contradiction between resistance to salinity accretion and maintaining high evaporation properties remains challenging bottleneck. Herein, we have developed biomimetic multiscale-ordered hydrogel-based solar evaporator for efficient The as-prepared consists of highly ordered ultralong hydroxyapatite (HAP) nanowires as supporting backbone heat insulator, MXene sunlight absorber, hydrophilic hyaluronic acid methacryloyl (HAMA) an interfacial bonding agent, modifier reduce enthalpy. MXene/ultralong HAP nanowires/HAMA (MHH) photothermal hydrogel with hierarchical structure mimics fish-gill structure. alignment realized at multiple scales, from nanoscale microscale macroscale 1D 2D 3D in evaporator. high-performance MHH exhibits efficiency conversion, low enthalpy, excellent management capability, performance. enthalpy decreases 2431 J g-1 (pure water) 1113 using As result, realize rate 6.278 kg m-2 h-1 under one sun illumination (1 kW m-2). Moreover, able achieve 4.931 real sample, exhibiting salt-rejecting It expected has promising applications desalination wastewater purification sustainable energy.

Language: Английский

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Hydrogel Toughening Resets Biomedical Application Boundaries

Progress in Polymer Science, Journal Year: 2025, Volume and Issue: unknown, P. 101929 - 101929

Published: Jan. 1, 2025

Language: Английский

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Failure Analysis of Composite Pre-tightened Multi-hierarchy Tooth Joint Based on Suture Structure

Journal of Bionic Engineering, Journal Year: 2025, Volume and Issue: 22(1), P. 262 - 281

Published: Jan. 1, 2025

Language: Английский

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Bioinspired Materials for Controlling Mineral Adhesion: From Innovation Design to Diverse Applications

ACS Nano, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 20, 2025

The advancement of controllable mineral adhesion materials has significantly impacted various sectors, including industrial production, energy utilization, biomedicine, construction engineering, food safety, and environmental management. Natural biological exhibit distinctive properties that inspire the design artificial systems for controlling adhesion. In recent decades, researchers have sought to create bioinspired effectively regulate adhesion, accelerating development functional across emerging fields. Herein, we review advances in mineralized antiscaling materials. First, a systematic overview nature is provided. Then, mechanism latest characterization between minerals material surfaces are introduced. Later, designed presented, ranging from molecular level micro/nanostructures, Additionally, applications these fields discussed, such as management, highlighting their roles promoting or inhibiting aspects. Finally, summarize ongoing challenges offer perspective on future this charming field.

Language: Английский

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Microwave-Heating-Assisted Synthesis of Ultrathin and Ultralong Hydroxyapatite Nanowires Using Biogenic Creatine Phosphate and Their Derived Flexible Bio-Paper with Drug Delivery Function

Molecules, Journal Year: 2025, Volume and Issue: 30(5), P. 996 - 996

Published: Feb. 21, 2025

With an ultrahigh aspect ratio and a similar chemical composition to the biomineral in bone tooth, ultralong hydroxyapatite nanowires (UHAPNWs) exhibit meritorious combination of high flexibility, excellent mechanical performance, biocompatibility, bioactivity. Despite these exciting merits, rapid green synthesis UHAPNWs remains challenging. In this work, we have developed environment-friendly, rapid, highly efficient ultrathin by microwave-assisted calcium oleate precursor hydrothermal method using biogenic creatine phosphate as bio-phosphorus source. Owing controllable hydrolysis bio-phosphorus-containing heating microwave irradiation, with homogeneous morphology several nanometers diameter (single nanowire), hundred micrometers length, ratios (>10,000) can be rapidly synthesized within 60 min. This effectively shortens time about two orders magnitude compared traditional method. Furthermore, are decorated situ bioactive self-assembled into nanowire bundles along their longitudinal direction at nanoscale. addition, relatively specific surface area 84.30 m2 g–1 ibuprofen drug loading capacity. The flexible bio-paper constructed from interwoven ibuprofen-loaded sustainably deliver phosphate-buffered saline, which is promising for various biomedical applications such tissue regeneration anti-inflammatory analgesic functions.

Language: Английский

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Metastable Calcium Phosphate Cluster‐Involved Mineralization Process Regulated by a Dual Biomolecule System Toward the Application in Dentinal Tubules Occlusion

Advanced Healthcare Materials, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 21, 2025

Dentin hypersensitivity caused by the exposure of dentinal tubules is affecting a significant portion population. With promising prospects, biomimetic mineralization materials used in treating dentin are expected to possess metastable characteristic, for which they can easily penetrate and surrounding tissues, but then occlude them via transformation size phase immediately. Herein, this study develops calcium phosphate cluster (MCPC)-involved process, regulated dual biological macromolecules: bovine serum albumin (BSA) poly-L-lysine (PLL). BSA functions stabilize primary clusters; PLL further tunes cluster's evolution (toward larger crystalline particles) into fashion, meanwhile inhibits local bacteria. Upon treatments, system generates amorphous MCPC with ultrasmall (1-2 nm); enter deep tubules, subsequently aggregate immobile particles, finally seal exposed tubules. The effective occlusion as well antibacterial performance confirmed both vivo vitro. This has devised not only regulatory approach mineralization-active clusters also established an efficient method managing hypersensitivity.

Language: Английский

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Control of Hydroxyapatite Mineralization in an Orthogonal Diffusion System

Crystal Growth & Design, Journal Year: 2025, Volume and Issue: unknown

Published: April 21, 2025

Language: Английский

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Twin-like chiral configuration of a calcium oxalate monohydrate mesocrystal regulated with an organic framework in grape leaves

CrystEngComm, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

Biogenic calcium oxalate monohydrate (COM, CaC 2 O 4 ·H O) needle crystals (raphides) having a pointed tip and two tails are arranged as bundle in grape leaves.

Language: Английский

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Biomimetic Scaffolds Regulating the Iron Homeostasis for Remolding Infected Osteogenic Microenvironment

Advanced Science, Journal Year: 2024, Volume and Issue: 11(44)

Published: Oct. 7, 2024

Abstract The treatment of infected bone defects (IBDs) needs simultaneous elimination infection and acceleration regeneration. One mechanism that hinders the regeneration IBDs is iron competition between pathogens host cells, leading to an deficient microenvironment impairs innate immune responses. In this work, in situ modification strategy proposed for printing iron‐active multifunctional scaffolds with homeostasis regulation ability treating IBDs. As a proof‐of‐concept, ultralong hydroxyapatite (HA) nanowires are modified through growth layer gallate (FeGA) followed by incorporation poly(lactic‐co‐glycolic acid) (PLGA) matrix print biomimetic PLGA based composite containing FeGA HA (FeGA‐HA@PLGA). photothermal effect endows excellent antibacterial activity. released ions from FeGA‐HA@PLGA help restore microenvironment, thereby promoting anti‐inflammatory, angiogenesis osteogenic differentiation. transcriptomic analysis shows exert anti‐inflammatory pro‐osteogenic differentiation activating NF‐κB, MAPK PI3K‐AKT signaling pathways. Animal experiments confirm repair performance IBDs, suggesting promising prospect therapy future clinical applications.

Language: Английский

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