Chiral supramolecular polymers

Chemical Society Reviews, Journal Year: 2023, Volume and Issue: 52(21), P. 7524 - 7548

Published: Jan. 1, 2023

Within the field of supramolecular polymers, chiral polymers are an excellent benchmark to generate helical structures that can clarify origin homochirality in Nature or find out new exciting functionalities organic materials.

Language: Английский

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Bio-Inspired Nanomaterials for Micro/Nanodevices: A New Era in Biomedical Applications

Micromachines, Journal Year: 2023, Volume and Issue: 14(9), P. 1786 - 1786

Published: Sept. 18, 2023

Exploring bio-inspired nanomaterials (BINMs) and incorporating them into micro/nanodevices represent a significant development in biomedical applications. Nanomaterials, engineered to imitate biological structures processes, exhibit distinctive attributes such as exceptional biocompatibility, multifunctionality, unparalleled versatility. The utilization of BINMs demonstrates potential diverse domains micro/nanodevices, encompassing biosensors, targeted drug delivery systems, advanced tissue engineering constructs. This article thoroughly examines the various BINMs, including those originating from proteins, DNA, biomimetic polymers. Significant attention is directed toward these entities subsequent ramifications that arise. review explores biomimicry’s structure–function correlations. Synthesis mosaics include bioprocesses, biomolecules, natural structures. These nanomaterials’ interfaces use functionalization geometric adaptations, transforming delivery, nanobiosensing, organ-on-chip cancer-on-chip models, wound healing dressing mats, antimicrobial surfaces. It provides an in-depth analysis existing challenges proposes prospective strategies improve efficiency, performance, reliability devices. Furthermore, this study offers forward-thinking viewpoint highlighting avenues for future exploration advancement. objective effectively utilize maximize application progression thereby propelling rapidly developing field its promising future.

Language: Английский

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Guidelines derived from biomineralized tissues for design and construction of high-performance biomimetic materials: from weak to strong

Chemical Society Reviews, Journal Year: 2024, Volume and Issue: 53(9), P. 4490 - 4606

Published: Jan. 1, 2024

This review discusses recent advances, challenges, future research directions and perspectives in biomineralized tissues, providing in-depth insights into derived guidelines for design preparation of high-performance biomimetic materials.

Language: Английский

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Tunable metal–organic frameworks assist in catalyzing DNAzymes with amplification platforms for biomedical applications

Chemical Society Reviews, Journal Year: 2023, Volume and Issue: 52(21), P. 7549 - 7578

Published: Jan. 1, 2023

Various binding modes of tunable metal organic frameworks (MOFs) and functional DNAzymes (Dzs) synergistically catalyze the emergence abundant nanoplatforms.

Language: Английский

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Rational Design of Bio‐Inspired Peptide Electronic Materials toward Bionanotechnology: Strategies and Applications

Advanced Functional Materials, Journal Year: 2024, Volume and Issue: 34(29)

Published: March 18, 2024

Abstract Biologically inspired peptide‐based materials, as novel charge transport have gained increasing interest in bioelectronics due to their remarkable electrical properties and inherent biocompatibility. Extensive studies shown that peptides can self‐assemble into a variety of hierarchical nanostructures with unique physical through supramolecular interactions. Therefore, materials hold great promise for applications emerging electronic fields such sensing, energy harvesting, storage, transmission. Herein, this work proposes review article summarize the rational design research progress devices bioelectronics. This first introduces strategies assembly mechanism constructing high‐performance devices. In following part, are systematically classified discussed, including sensors, piezoelectric nanogenerators, electrodes, semiconductors. Finally, remaining challenges future perspectives bioelectronic presented. believes will provide inspiration guidance development innovative smart field

Language: Английский

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Peptide nanozymes: An emerging direction for functional enzyme mimics

Bioactive Materials, Journal Year: 2024, Volume and Issue: 42, P. 284 - 298

Published: Sept. 4, 2024

Language: Английский

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Bioinspired Composite Hydrogels with Osteogenic, Angiogenic, and Antioxidant Properties for Enhanced Bone Repair

Small Structures, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 28, 2025

The increasing demand of advanced biomedical materials for bone repair and regeneration has spurred significant research in recent years. While traditional hydrogels offer promising biocompatibility easy fabrication, their application reconstruction is often impeded by inadequate structural integrity biological functions. Graphene oxide (GO) emerged as a transformative additive, renowned its exceptional mechanical chemical properties, well ability to enhance the hydrogels. In this study, incorporation GO into chitosan (CS) investigated, achieving bioinspired with enhanced strength stability, which are crucial supporting regeneration. Additionally, self‐assembled synthetic peptide nanofibers (PNFs) employed facilitate biomimetic mineralization hydrogels, critical process effective remodeling. This innovative composite hydrogel not only achieves but also exhibits osteogenic, pro‐angiogenic, antioxidant properties essential repair. novel method takes advantage distinctive GO, PNFs, biomass providing robust material solution potential significantly advance field tissue engineering.

Language: Английский

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Exploiting Silica-Binding and Silica-Forming Proteins as Versatile Tools for One-Step Enzyme Immobilization on Siliceous Materials

International Journal of Molecular Sciences, Journal Year: 2025, Volume and Issue: 26(3), P. 1304 - 1304

Published: Feb. 3, 2025

Enzyme immobilization has emerged as an essential technique in industrial applications of enzymes. Silica (SiO2) serves a prominent support material for enzyme immobilization. Recent advancements have led to the development various silica-binding proteins (SBPs) and silica-forming (SFPs) that are invaluable tools immobilizing enzymes on siliceous materials fast simple manner. SBPs facilitate with controlled orientation silica surfaces, while SFPs enable biomimetic synthesis encapsulation within particles. In this review, we explore recent advances use applications. We provide comprehensive overview their mechanisms sequence characteristics relevant Additionally, summarize recombinant production procedures or SFPs. then categorize available into naturally occurring artificially engineered types, presenting examples demonstrate utilization Our review highlights strengths limitations sheds light future directions tailor-made biocatalytic silica.

Language: Английский

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Modular Design of Lipopeptide‐Based Organ‐Specific Targeting (POST) Lipid Nanoparticles for Highly Efficient RNA Delivery

Advanced Materials, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 9, 2025

Lipid nanoparticles (LNPs) with highly efficient and specific extrahepatic targeting abilities are promising in gene delivery, the lipopeptides (LPs) excellent designability functionality expected to empower construction of functional LNPs. This study aims develop ionizable components that accurately match different lipid systems through modular design LPs. Based on this, a lipopeptide-based organ-specific (POST) LNP screening strategy is constructed, which lysine-histidine-based (KH-LPs) designed as components. The optimal KH-LP screened vitro shows siRNA/mRNA transfecting ability various hard-to-transfect cell lines. Compared classic LNPs, POST LNPs vivo achieve even higher (or at least comparable) efficiency specificity delivering mRNA siRNA lung, liver, spleen, respectively. structure-activity relationship (SAR) proves regulation LP structures can provide for systems, demonstrating potential this developing selective open up more possibilities therapy.

Language: Английский

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Preparation of chiral polymers: precise chirality transfer from natural species to achiral artificial polymers

Giant, Journal Year: 2023, Volume and Issue: 14, P. 100161 - 100161

Published: April 27, 2023

The synthesis of chiral substances, especially polymers is currently one the hottest issues in field materials and chemistry due to their unique structural characteristics potential applications. However, acquisition by chemical or asymmetric catalysis may often involve expensive reagents tedious routes. types substances nature are undoubtedly limited. Except for design compounds, utilizing external stimulus factors induce chirality achiral a promising approach. Inspired nature, researchers tend rational interaction systems that attempt precisely transfer information from natural species artificial polymers, which has been proven be an excellent method construct macro-molecular/supramolecular polymer systems. In this review, account typical development naturally occurring including dopants, solvents, summarized. Finally, we further briefly introduce future scope, opportunities, challenges developing novel functional polymeric materials.

Language: Английский

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