Crystals,
Journal Year:
2025,
Volume and Issue:
15(4), P. 322 - 322
Published: March 28, 2025
The
selective
adsorption
and
separation
of
benzene
from
structurally
similar
six-membered
hydrocarbons
fluorocarbons
remain
a
significant
challenge
due
to
their
comparable
physical
properties.
In
this
study,
we
investigated
the
molecular
recognition
properties
perfluorinated
triketonate
Cu(II)
complex
(1)
as
Nonporous
Adaptive
Crystal
(NAC).
addition
previously
reported
(2)-encapsulated
crystal
1•(2)3,
report
here
structures
guest-free
1
cyclohexene
(3)-encapsulated
1•(O)2•3,
where
(O)2
represents
two
water
molecules.
Single-crystal
analysis
demonstrated
that
selectively
encapsulates
2
while
excluding
other
hydrocarbons,
including
3,
cyclohexane
(4),
trifluorobenzene
(5),
hexafluorobenzene
(6).
Gas
experiments
confirmed
high
affinity
for
2,
reflected
in
its
preferential
behavior
mixed
solvent
vapor
environments.
selectivity
was
attributed
strong
π-hole···π
metal···π
interactions,
which
favor
electron-rich
aromatic
guests.
Additionally,
crystallization
competitive
systems
consistently
led
formation
reinforcing
2.
These
findings
highlight
unique
capabilities
NACs,
providing
valuable
insights
into
rational
design
advanced
materials
industrial
applications
involving
hydrocarbons.
Hirshfeld
surface
revealed
contribution
F···F
interactions
packing
decreased
upon
guest
(48.8%
1,
34.2%
22.2%
1•(2)3),
F···H/H···F
increased
(8.6%
35.4%
1•(2)3).
Regarding
Cu
self-assembled
columnar
structure
results
close
contacts
at
coordination
sites,
Cu···Cu
(0.1%),
Cu···O
(0.7%),
Cu···C
(1.3%).
However,
guest-incorporated
1•(O)2•3
disappears;
instead,
exhibits
increase
(1.2%),
corresponding
coordination,
1•(2)3
shows
an
(1.5%),
indicative
benzene.
Nature Communications,
Journal Year:
2024,
Volume and Issue:
15(1)
Published: Feb. 10, 2024
Abstract
The
combination
of
macrocyclic
chemistry
with
co-crystal
engineering
has
promoted
the
development
materials
vapochromic
behaviors
in
supramolecular
science.
Herein,
we
develop
a
macrocycle
based
on
hybrid[4]arene
and
1,2,4,5-tetracyanobenzene
that
is
able
to
construct
materials.
After
capture
benzene
toluene
vapors,
activated
hybrid[4]arene-based
forms
new
structures,
accompanied
by
color
changes
from
brown
yellow.
However,
when
captures
cyclohexane
pyridine,
neither
structures
nor
colors
change.
Interestingly,
can
separate
benzene/cyclohexane
equal-volume
mixture
allow
be
removed
toluene/
pyridine
purities
reaching
100%.
In
addition,
process
adsorptive
separation
visually
monitored.
selectivity
attributed
different
charge-transfer
interaction
between
vapors.
Moreover,
reused
without
losing
performance.
This
work
constructs
material
for
hydrocarbon
separation.
Journal of the American Chemical Society,
Journal Year:
2024,
Volume and Issue:
146(9), P. 6225 - 6230
Published: Feb. 22, 2024
Per-
and
polyfluoroalkyl
substances
(PFAS)
accumulate
in
water
resources
pose
serious
environmental
health
threats
due
to
their
nonbiodegradable
nature
long
persistence
times.
Strategies
for
the
efficient
removal
of
PFAS
from
contaminated
are
needed
address
this
concern.
Here,
we
report
a
fluorinated
nonporous
adaptive
crystalline
cage
(F-Cage
2)
that
exploits
electrostatic
interaction,
hydrogen
bonding,
F–F
interactions
achieve
perfluorooctanoic
acid
(PFOA)
aqueous
source
phases.
F-Cage
2
exhibits
high
second-order
kobs
value
approximately
441,000
g
mg–1
h–1
PFOA
maximum
adsorption
capacity
45
mg
g–1.
can
decrease
concentrations
1500
6
ng
L–1
through
three
rounds
flow-through
purification,
conducted
at
flow
rate
40
mL
h–1.
Elimination
PFOA-loaded
is
readily
achieved
by
rinsing
with
mixture
MeOH
saturated
NaCl.
Heating
80
°C
under
vacuum
then
makes
ready
reuse,
as
demonstrated
across
five
successive
uptake
release
cycles.
This
work
thus
highlights
potential
utility
suitably
designed
crystals
platforms
remediation.
Science,
Journal Year:
2024,
Volume and Issue:
386(6725), P. 1037 - 1042
Published: Nov. 28, 2024
Aromatic
-
aliphatic
hydrocarbon
separation
is
a
challenging
but
important
industrial
process.
Pervaporation
membrane
technology
has
the
potential
for
separating
these
mixtures.
We
developed
an
oriented
monolayer
polyhedral
(OMP)
that
consists
of
ordered
particles
and
anchored
by
hyperbranched
polymers.
It
contains
high
density
straight,
selective
nanochannels,
enabling
preferential
transport
aromatic
molecules.
Compared
with
traditional
mixed-matrix
membranes
random
orientations,
OMP
improves
pervaporation
index
aromatic-aliphatic
mixtures
C
6
7
compounds,
surpassing
performance
existing
3
to
10
times.
This
demonstrates
molecular
their
application
in
value-added
naphtha
feedstocks.
Materials Chemistry Frontiers,
Journal Year:
2024,
Volume and Issue:
8(10), P. 2273 - 2281
Published: Jan. 1, 2024
An
efficient
strategy
for
separation
of
xylene
isomers
in
both
vapor
and
liquid
phases
based
on
nonporous
adaptive
crystals
hybrid[3]arene
is
developed,
showing
good
performance
high
recyclability
o
-xylene,
providing
a
new
method
isomers.
Chemistry of Materials,
Journal Year:
2024,
Volume and Issue:
36(3), P. 1631 - 1638
Published: Jan. 18, 2024
Ortho-chlorotoluene
serves
as
a
vital
raw
material
in
the
petrochemical
industries.
However,
due
to
alkylation
and
chlorination,
ortho-chlorotoluene
is
often
mixed
with
meta-chlorotoluene
para-chlorotoluene.
The
selective
separation
of
from
chlorotoluene
isomers
crucial
step
industrial
production.
owing
close
boiling
points
isomers,
traditional
methods
demand
large
amount
energy.
Therefore,
there
an
urgent
need
develop
new
achieve
efficient
isomers.
Herein,
we
developed
adsorptive
strategy
using
nonporous
adaptive
crystals
hybrid[3]arene
H
(Hα).
Hα
was
proved
be
highly
effective
binary
or
ternary
mixture
Single-crystal
structure
analysis
electrostatic
potential
maps
indicated
that
selectivity
derived
stable
host–guest
between
H.
Besides,
exhibited
high
recyclability
reversible
transformation
guest-free
guest-contained
structures.
Frontiers in Immunology,
Journal Year:
2025,
Volume and Issue:
16
Published: Jan. 22, 2025
Cell
penetrating
peptides
(CPPs)
are
usually
positive
charged
and
have
good
cell
membrane
permeability.
Meanwhile,
CPPs
facile
to
synthesize,
can
be
functionalized
satisfy
different
demands,
such
as
cyclization,
incorporating
unnatural
amino
acids,
lipid
conjugation.
These
properties
made
them
efficient
drug-delivery
tools
deliver
therapeutic
molecules
cells
tissues
in
a
nontoxic
manner,
including
small
molecules,
DNA,
siRNA,
proteins
other
various
nanoparticles.
However,
the
poor
serum
stability
low
tumor
targeting
ability
also
hindered
their
broad
application.
Besides,
inappropriate
chemical
modification
lead
disruption
nonspecific
toxicity.
In
this
paper,
we
first
reviewed
recent
advances
CPP
applications
for
cancer
therapy
via
covalent
or
non-covalent
manners.
We
carefully
analyzed
advantages
disadvantages
of
each
modifications
drug
delivery.
Then,
concluded
progress
clinical
trials
diseases.
Finally,
discussed
challenges
opportunities
met
translate
into
applications.
This
review
presented
new
insight
delivery,
which
could
provide
advice
on
design
clinically
effective
systemic
delivery
systems
using
CPPs.
ACS Applied Materials & Interfaces,
Journal Year:
2024,
Volume and Issue:
16(4), P. 4863 - 4872
Published: Jan. 18, 2024
A
butterfly-shaped
phenothiazine
derivative,
PTTCN,
was
synthesized
to
obtain
pure
organic
porous
crystals
for
the
highly
efficient
absorptive
separation
of
toluene
(Tol)
and
methylcyclohexane
(Mcy).
Due
presence
three
polar
cyano
groups
nonplanar
conformation,
these
molecules
self-assembled
into
a
hydrogen-bonded
framework
(X-HOF-5)
with
distinct
cavities
capable
accommodating
Tol
through
multiple
hydrogen-bonding
interactions.
Upon
solvent
removal
via
heating,
activated
X-HOF-5
retained
its
cavity
structure
albeit
altered
stacking
arrangements,
accompanied
by
remarkable
fluorescent
color
change
from
cyan
green.
X-HOF-5a
can
undergo
phase
transformation
upon
reabsorption
Tol,
while
exhibiting
no
accommodation
Mcy
due
weak
intermolecular
interaction
between
PTTCN
Mcy.
This
suggests
that
HOF
material
prefers
over
Moreover,
may
selectively
accommodate
in
Tol/Mcy
equimolar
mixture,
purity
reach
97%
after
release
framework.
Additionally,
it
is
noteworthy
exhibits
recyclability
without
any
discernible
loss
performance.
Journal of Nanobiotechnology,
Journal Year:
2024,
Volume and Issue:
22(1)
Published: May 21, 2024
Transdermal
delivery
of
sparingly
soluble
drugs
is
challenging
due
to
their
low
solubility
and
poor
permeability.
Deep
eutectic
solvent
(DES)/or
ionic
liquid
(IL)-mediated
nanocarriers
are
attracting
increasing
attention.
However,
most
them
require
the
addition
auxiliary
materials
(such
as
surfactants
or
organic
solvents)
maintain
stability
formulations,
which
may
cause
skin
irritation
potential
toxicity.
