Paired Electrolysis-Enabled Arylation of Quinoxalin-2(1H)-ones

The Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: 89(9), P. 6117 - 6125

Published: April 24, 2024

The first paired electrolysis-enabled arylation of quinoxalin-2(1H)-ones was achieved using cyanoarenes as the reagents. A variety 3-arylquinoxalin-2(1H)-ones with various important functional groups were obtained in moderate to good yields under metal- and chemical oxidant-free conditions. With a pair reductive oxidative processes occurring among substrates reaction intermediates, power consumption can be dramatically reduced.

Language: Английский

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Sono-photocatalytic amination of quinoxalin-2(1H)-ones with aliphatic amines

Chinese Chemical Letters, Journal Year: 2024, Volume and Issue: 35(10), P. 110038 - 110038

Published: May 22, 2024

Language: Английский

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Self-Catalyzed Sono-Photoinduced Arylation of Quinoxalin-2(1H)-ones with Arylhydrazines

The Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 25, 2024

Herein, the first example of self-catalyzed sono-photoinduced carbon-carbon bond formation was described. Combining advantages phototriggered self-catalysis and ultrasonic catalysis, a wide range 3-arylquinoxalin-2(1

Language: Английский

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Mn-Mediated Direct Regioselective C–H Trifluoromethylation of Imidazopyridines and Quinoxalines

The Journal of Organic Chemistry, Journal Year: 2023, Volume and Issue: 88(15), P. 10599 - 10608

Published: July 20, 2023

A simple and highly efficient strategy has been developed for direct C-H trifluoromethylation at C-3 of imidazopyridines C-8 quinoxalines with readily available Langlois reagent through KMnO4/AcOH system. This protocol showed broad substrate scope afforded moderate-to-excellent yields both products. It is the first report that functionalization occurred regioselectively position quinoxalines. Mechanistic studies revealed reaction proceeded via radical pathway.

Language: Английский

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Recent advancements in visible-light-induced direct C(3)–H functionalization of quinoxalin-2(1H)-ones

Green Synthesis and Catalysis, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 1, 2024

Language: Английский

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Recent Advances in Photo-promoted Generalized C3-H Alkylation of Quinoxalin-2(1H)-ones

Organic & Biomolecular Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

Recent advances in the photo-promoted C3–H alkylation reaction of quinoxalin-2(1 H )-ones with different agents.

Language: Английский

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Advances in Photoinduced Minisci-like Reactions

Synthesis, Journal Year: 2024, Volume and Issue: unknown

Published: July 29, 2024

Abstract The Minisci reaction, which has been around for more than five decades, is still the preferred tool straightforward alkylation of basic heteroarenes. recent developments in photocatalysis have opened novel pathways radical generation under milder and sustainable conditions. Implementing this approach into reaction renewed interest transformation, attractive per se Medicinal Chemistry. Aspects such as sacrificial oxidants, catalysts, specific conditions should be carefully examined to evaluate practicability protocol. This short review focuses on advances (2020 February 2024) photoinduced Minisci-type reactions, emphasizing sustainability. 1 Introduction 2 Using Noble-Metal-Based Photocatalysts 3 Noble-Metal-Free Methods Sacrificial Oxidants 4 Without 5 Conclusions Perspectives

Language: Английский

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Lewis Acid-Mediated Isothiocyanation and Chlorination of Quinoxalin-2(1H)-ones under Visible Light Conditions

The Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: 89(15), P. 10760 - 10772

Published: July 11, 2024

Lewis acid-mediated selective C3-isothiocyanation of quinoxalin-2(1

Language: Английский

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Recent applications of phenyl hydrazine in photoinduced chemical transformations

Synthetic Communications, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 23

Published: Dec. 3, 2024

Phenyl hydrazine has attracted attention in photoredox catalytic synthetic strategies for the formation of carbon-carbon (C-C) bond and Carbon-Heteroatom (C-N, C = N, C-P, C-S, S-N) bonds, because low cost ease availability make it a promising alternative method typical transition metal complex-based photocatalyzed synthesis. In this review, we have focused on recent radical coupling ­reactions phenyl via photochemical to form carbon–carbon carbon–heteroatom (N, P, S) bonds along with mechanism involved their reaction.

Language: Английский

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Radical‐Induced C−H Direct Activation of Quinoxaline via Visible Light Photoredox‐Catalyzed

Asian Journal of Organic Chemistry, Journal Year: 2023, Volume and Issue: 12(12)

Published: Oct. 12, 2023

Abstract The photocatalytic C(sp 2 )−H functionalization of quinoxaline derivatives using potassium iodide as photoredox‐mediators has been described. lower price compared to standard photocatalysts, readily available substrates, and environmental solvent constitute make this method cost‐effective interesting. A catalytic amount KI is applied the direct activation C−H bonds for construction heterocyclic compound. This system simple operation, characteristics easy obtain raw materials, high yield excellent substrate adaptability provide a new synthesis C2 substituent quinoxalines.

Language: Английский

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