The concentration of dissolved organic matter impacts the neurobehavior in zebrafish larvae exposed to cyclophosphamide DOI

Tianming Liu,

Dongshen Shang,

Weiqi Tian

et al.

Environmental Science and Pollution Research, Journal Year: 2024, Volume and Issue: 31(51), P. 61181 - 61190

Published: Oct. 15, 2024

Language: Английский

Evaluation of the detoxification effect and toxicity mechanism of Fenton process for pulping wastewater treatment DOI

Fei Di,

Donghui Han,

Jinquan Wan

et al.

Journal of Water Process Engineering, Journal Year: 2025, Volume and Issue: 70, P. 107041 - 107041

Published: Jan. 22, 2025

Language: Английский

Citations

1
Developmental toxicity of the emerging contaminant cyclophosphamide and the integrated biomarker response (IBRv2) in zebrafish DOI
Tamilselvan Hema, Rama-Krishnan Poopal, Mathan Ramesh

et al.

Environmental Science Processes & Impacts, Journal Year: 2023, Volume and Issue: 25(8), P. 1391 - 1406

Published: Jan. 1, 2023

The safety of cyclophosphamide (CP) in the early developmental stages is not studied yet; it important to study responses at these because they might have relevance CP-administered humans. We toxicity CP by analysing physiological, morphological, and oxidative stress, neurotransmission enzymes, gene expression histological endpoints zebrafish embryos/larvae. lasted for 120 hpf environmentally relevant concentrations CP. No visible alterations were noticed control group. Delayed hatching, slow heart rate, yolk sac oedema, pericardial morphological deformities, incompetence stress biomarkers, excessive generation ROS, apoptosis, inhibition neurotransmitters histopathological anomalies observed CP-treated groups. These found be concentration- duration-dependent effects physiological endpoints, whereas concentration-dependent antioxidants, apoptosis endpoints. Biomarkers standardised using integrated biomarker response-IBRv2 index. IBRv2 index showed a behaviour. A non-lethal teratogenic effect was embryos/larvae concentrations. biomarkers are sensitive, interrelated; thus, their useful assess veiled unseen hazards pharmaceuticals.

Language: Английский

Citations

5
Perturbations in Redox Status, Biochemical Indices, and Expression of XBP1s and NOX4 in the Livers of Channa Punctatus Following Exposure to Mancozeb DOI Creative Commons

Adeel Ahmad Khan,

Shikha Dwivedi, Shefalee Singh

et al.

Gene Expression, Journal Year: 2024, Volume and Issue: 000(000), P. 000 - 000

Published: Jan. 2, 2024

Background and objectivesDue to the increased demand for food growing population, pesticides are widely used control diseases boost productivity. This study was designed evaluate toxic effects of fungicide, Mancozeb (MZ), in liver fish strain Channa punctatus.

Language: Английский

Citations

1
The concentration of dissolved organic matter impacts the neurobehavior in female zebrafish exposed to cyclophosphamide DOI

Tianming Liu,

Heru Dong,

Jianxing Zhao

et al.

Comparative Biochemistry and Physiology Part C Toxicology & Pharmacology, Journal Year: 2024, Volume and Issue: 278, P. 109866 - 109866

Published: Feb. 17, 2024

Language: Английский

Citations

1
The toxic effect of 2,6-di-tert-butylphenol on embryonic development in zebrafish (Danio rerio): decreased survival rate, morphological abnormality, and abnormal vascular development DOI
Juan Liu, Huiyun Wang, Mingyang Lu

et al.

Environmental Research, Journal Year: 2024, Volume and Issue: 262, P. 119881 - 119881

Published: Aug. 29, 2024

Language: Английский

Citations

1
The concentration of dissolved organic matter impacts the neurobehavior in zebrafish larvae exposed to cyclophosphamide DOI

Tianming Liu,

Dongshen Shang,

Weiqi Tian

et al.

Environmental Science and Pollution Research, Journal Year: 2024, Volume and Issue: 31(51), P. 61181 - 61190

Published: Oct. 15, 2024

Language: Английский

Citations

0