Synthesis of Indenones via Persulfate Promoted Radical Alkylation/Cyclization of Biaryl Ynones with 1,4-Dihydropyridines DOI Creative Commons
Wanwan Wang, Lei Yu

Molecules, Journal Year: 2024, Volume and Issue: 29(2), P. 458 - 458

Published: Jan. 17, 2024

The oxidative radical cascade cyclization of alkynes has emerged as a versatile strategy for the efficient construction diverse structural units and complex molecules in organic chemistry. This work reports an alkyl initiated 5-exo-trig biaryl ynones with 1,4-dihydropyridines to selectively synthesize indenones.

Language: Английский

EDA Complex-Enabled Annulation to Access CF2-Containing Tetralones and Quinazolinones Using Persulfates as Electron Donors DOI
Shupeng Zhang, Dawei Guo,

Mei-Ling Yang

et al.

The Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: 89(15), P. 10614 - 10623

Published: July 25, 2024

A photocatalyst-free and EDA complex-enabled radical cascade cyclization reaction of inactive alkenes with bromodifluoroacetamides was reported for the divergent synthesis fluorine-containing tetralones quinazolinones. In this transformation, persulfates as electron donors difluoro bromamide acceptors generate complex. This is a promising photochemical method advantages such mild conditions, simple operation, being metal-free, excellent functional group tolerance.

Language: Английский

Citations

6
K2S2O8-Induced [4+2] Annulation of Tertiary Anilines and Alkenes toward Tetrahydroquinolines DOI
Jianguo Hu, Shengchun Wang, Bin Li

et al.

Organic Letters, Journal Year: 2023, Volume and Issue: 25(8), P. 1252 - 1256

Published: Feb. 22, 2023

Due to the unique physicochemical properties of heterocyclic compounds, their construction is one central issues in synthetic chemistry. Here, we report a K2S2O8-induced protocol for constructing tetrahydroquinolines from bulk chemicals (alkenes and anilines). The merit this method has been demonstrated by its operational simplicity, wide scope, mild conditions, transition-metal-free system.

Language: Английский

Citations

11
In-situ and ex-situ selective catalysis of biochar-based catalysts for the production of high-quality bio-oil and H2-rich gas from tobacco stem DOI
Xin Tang, Xiang Li,

Qiu Fa He

et al.

Journal of environmental chemical engineering, Journal Year: 2024, Volume and Issue: 12(6), P. 114268 - 114268

Published: Sept. 26, 2024

Language: Английский

Citations

4
[2+2+2] Cycloadditions DOI
Ángel Manu Martínez, Gema Domı́nguez, Javier Pérez‐Castells

et al.

Elsevier eBooks, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

Citations

0
Recent advances in radical-mediated intermolecular (4 + 2) cycloaddition DOI

Xue‐Er Cai,

Ziying Wang,

Wen‐Chan Tian

et al.

Organic & Biomolecular Chemistry, Journal Year: 2023, Volume and Issue: 21(30), P. 6068 - 6082

Published: Jan. 1, 2023

On the basis of types radicals that initiate different intermolecular (4 + 2) cycloaddition processes, we classify them into five types, and this review places special emphasis on reaction design mechanisms.

Language: Английский

Citations

8
Silver-catalyzed cyclization of α-imino-oxy acids to fused tetralone derivatives DOI
Kai Liu, Feng Li, Jingjing Wang

et al.

Organic & Biomolecular Chemistry, Journal Year: 2023, Volume and Issue: 21(13), P. 2700 - 2704

Published: Jan. 1, 2023

A silver-catalyzed cyclization of α-imino-oxy acids under mild conditions has been described. This reaction offers facile access to a diverse range fused tetralone derivatives with exquisite stereoselectivity in moderate good yields.

Language: Английский

Citations

4
Assembly of Functionalized 3,4‐Fused Tricyclic Benzosultams via Radical‐Promoted Cascade Reactions DOI
Chada Raji Reddy,

Ankita Kumari,

Banoth Karuna Sagar

et al.

Advanced Synthesis & Catalysis, Journal Year: 2024, Volume and Issue: 366(17), P. 3624 - 3630

Published: June 21, 2024

Abstract A tandem oxidative radical functionalization/annulation of N ‐acryloyl amino saccharin is disclosed. This strategy allows the facile construction diversely functionalized 3,4‐fused tricyclic benzosultams that previously have not been reported. wide range functionalities were installed through formation C−C, C−S and C−P bond enabled by respective radicals.

Language: Английский

Citations

1
Synthesis of Indenones via Persulfate Promoted Radical Alkylation/Cyclization of Biaryl Ynones with 1,4-Dihydropyridines DOI Creative Commons
Wanwan Wang, Lei Yu

Molecules, Journal Year: 2024, Volume and Issue: 29(2), P. 458 - 458

Published: Jan. 17, 2024

The oxidative radical cascade cyclization of alkynes has emerged as a versatile strategy for the efficient construction diverse structural units and complex molecules in organic chemistry. This work reports an alkyl initiated 5-exo-trig biaryl ynones with 1,4-dihydropyridines to selectively synthesize indenones.

Language: Английский

Citations

1