Molecular Catalysis, Journal Year: 2024, Volume and Issue: 569, P. 114563 - 114563
Published: Sept. 25, 2024
Language: Английский
Organic Letters, Journal Year: 2023, Volume and Issue: 25(3), P. 494 - 499
Published: Jan. 12, 2023
The annulation reactions of N-allylbenzamides with N-sulfonylaminopyridinium salts were developed under metal-free photoinduced mild conditions. Substituent-controlled sulfonaminoarylation and sulfonaminooxylation benzamides realized: lead to benzosultams, while N-(2-phenylallyl)benzamides give sulfonamidylated oxazoline derivatives. Control experiments indicated that those undergo a radical pathway arylsulfonamidyl radicals as the intermediates. aryl C–H bond functionalization in was involved for first time benzosultams.
Language: Английский
Citations
24
Chemical Communications, Journal Year: 2023, Volume and Issue: 59(19), P. 2767 - 2770
Published: Jan. 1, 2023
Radical-mediated photoredox hydroarylation reaction of unactivated alkenes using thiosulfonate compounds as key radical precursors to synthesize pyridyquinazolinone and pyrroloquinazolinone derivatives is described.
Language: Английский
Citations
23
Organic Letters, Journal Year: 2023, Volume and Issue: 25(10), P. 1683 - 1688
Published: March 8, 2023
A visible-light-induced hydrocyclization of unactivated alkenes was developed using 3CzClIPN as the photocatalyst to generate substituted α-methyldeoxyvasicinones and α-methylmackinazolinones in moderate good yields. An intermolecular hydrogen atom transfer with THF source involved. Mechanism studies indicated that intramolecular addition situ formed aminal radical alkene generated polycyclic quinazolinone.
Language: Английский
Citations
23
Asian Journal of Organic Chemistry, Journal Year: 2023, Volume and Issue: 12(5)
Published: April 8, 2023
Abstract Ring‐fused polycyclic structures widely exist in a myriad of natural products and pharmaceutical molecules. Consequently, the construction such from readily available substrates becomes an important researching topic organic synthesis. Triggered by addition radicals to (activated or unactivated) double bonds alkenes, subsequent intramolecular addition/cyclization leads compounds. Following this procedure, variety functionalized ring‐fused were formed. Great achievements have been witnessed recently. Those works provided efficient, atom economy, operational simple approaches toward versatile alkene‐based substrates. Here, we summarized recent on formation via radical‐triggered cascade reactions alkenes. Construction with no less than 3 fused rings developed during last decade included Review, corresponding mechanisms also discussed.
Language: Английский
Citations
23
Advanced Synthesis & Catalysis, Journal Year: 2024, Volume and Issue: 366(4), P. 635 - 697
Published: Jan. 13, 2024
Abstract In recent years, the interest to develop cyclizations promoted by visible light has been gaining a lot of attention due its sustainability aspect. this review, we summarize most important advances in period describing methods used generate different ring sizes, while focusing on mechanistic details these reactions.
Language: Английский
Citations
8
Organic Chemistry Frontiers, Journal Year: 2023, Volume and Issue: 10(14), P. 3479 - 3484
Published: Jan. 1, 2023
A visible-light induced radical cyclization of olefinic amides with easily available N -sulfonylaminopyridinium salts towards iminoisobenzofurans and benzoxazines has been developed.
Language: Английский
Citations
16
Organic Chemistry Frontiers, Journal Year: 2023, Volume and Issue: 10(21), P. 5470 - 5477
Published: Jan. 1, 2023
A photocatalytic, regio- and stereoselective olefinic β-C–H sulfamoylation of enamides with commercially available sulfamoyl chlorides was developed.
Language: Английский
Citations
12
Chemical Communications, Journal Year: 2024, Volume and Issue: 60(18), P. 2556 - 2559
Published: Jan. 1, 2024
3-(2-Isocyanophenyl)quinazolin-4(3 H )-ones were designed and synthesized as new building units for the construction of novel quinoxalino[2,1- b ]quinazolinones under mild, photocatalytic metal-free conditions.
Language: Английский
Citations
5
Organic Letters, Journal Year: 2023, Volume and Issue: 25(13), P. 2300 - 2305
Published: March 27, 2023
Here we report facile and manipulable access to methylenebisamide derivatives via visible-light-driven radical cascade processes incorporating C(sp3)–H activation C–N/N–O cleavage. Mechanistic studies reveal that a traditional Ir-catalyzed photoredox pathway novel copper-induced complex-photolysis are both involved, contributing activating the inert N-methoxyamides rendering valuable bisamides. This approach exhibits many advantages, including mild reaction conditions, broad scope functional group tolerance, competitive step economy. Given mechanistic plenitude operational simplicity, believe this package deal paves promising way for synthesis of nitrogen-containing molecules.
Language: Английский
Citations
10
The Journal of Organic Chemistry, Journal Year: 2023, Volume and Issue: 89(1), P. 644 - 655
Published: Dec. 13, 2023
A photoredox-catalyzed intermolecular tandem sulfonamination/cyclization of enaminones was realized by using N-aminopyridinium salts as the sulfonaminated reagents without transition-metal catalysts or bases. The reaction exhibits a broad scope and good functional group tolerance, yields, regioselectivity. Preliminary mechanistic studies support radical property involvement N-centered intermediates.
Language: Английский
Citations
10