A Standalone and Portable Imaging Detection System with Embedded Computing for Automated Defect Inspection of Microfluidic Devices DOI
Shuo Yang, Xin Feng, Qingzheng Wang

et al.

Journal of Micromechanics and Microengineering, Journal Year: 2024, Volume and Issue: 34(8), P. 085013 - 085013

Published: July 19, 2024

Abstract The existing methods for defect detection in PDMS microfluidic chips typically involve complex image recognition algorithms or manual inspection and still lack efficiency reliability. Although some automatic have been proposed recent years, most of them rely on external computation systems to deploy. To address these challenges, we propose an independent portable system with embedded computing devices. This is completely self-contained, integrating acquisition module, a control panel power module realize chip detection, processing, result display functions. Experimental results show that the can effectively detect commonly seen defects PDMS-based chips, proving be more efficient reliable than inspection. With system, two methods: template matching (based comparison standard samples) surface recognition) were used identify chips. automatically inspect analyze without need laboratory support provide promising solution future manufacturing operation.

Language: Английский

Microfluidics for personalized drug delivery DOI Creative Commons
Seyed Ebrahim Alavi, Sitah Alharthi,

Seyedeh Fatemeh Alavi

et al.

Drug Discovery Today, Journal Year: 2024, Volume and Issue: 29(4), P. 103936 - 103936

Published: Feb. 29, 2024

This review highlights the transformative impact of microfluidic technology on personalized drug delivery. Microfluidics addresses issues in traditional synthesis, providing precise control and scalability nanoparticle fabrication, platforms show high potential for versatility, offering patient-specific dosing real-time monitoring capabilities, all integrated into wearable technology. Covalent conjugation antibodies to nanoparticles improves bioactivity, driving innovations targeting. The integration microfluidics with sensor technologies artificial intelligence facilitates feedback autonomous adaptation delivery systems. Key challenges, such as droplet polydispersity fluidic handling, along future directions focusing reliability, are essential considerations advancing

Language: Английский

Citations

23

Recent advances in Organ-on-a-Chip models: How precision engineering integrates cutting edge technologies in fabrication and characterization DOI
Sorour Sadeghzade, Mohammad Hosseini Hooshiar, Hossein Akbari

et al.

Applied Materials Today, Journal Year: 2024, Volume and Issue: 38, P. 102231 - 102231

Published: May 14, 2024

Language: Английский

Citations

9

Quantum photonics sensing in biosystems DOI Creative Commons
Ekaterina Moreva, Valeria Cimini, Ilaria Gianani

et al.

APL Photonics, Journal Year: 2025, Volume and Issue: 10(1)

Published: Jan. 1, 2025

Quantum sensors emerged among quantum technologies as the ones with promising potential applications in near future. This perspective reviews two leading sensing platforms and their advancements toward biological applications: light sources color centers diamonds. light, including squeezed states N00N states, allows enhanced phase measurements by surpassing classical shot noise limits. advantage can be exploited several contexts, enabling improved resolution sensitivity, which are particularly valuable contexts where traditional high-intensity illumination could damage or alter delicate samples. In parallel, diamonds, specifically nitrogen-vacancy silicon-vacancy centers, also for due to high sensitivity biocompatibility. These enable detailed intracellular measurements, such temperature detection, show measuring magnetic fields of origin. Despite these advancements, significant challenges remain translating from a controlled laboratory environment practical, widely applicable devices diverse applications. Overcoming is crucial unlocking full field.

Language: Английский

Citations

1

Advancing microfluidic design with machine learning: a Bayesian optimization approach DOI Creative Commons
Ivana Kundačina, Ognjen Kundačina, Dragiša Mišković

et al.

Lab on a Chip, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

The proposed Bayesian optimization-based approach enhances micromixer performance by optimizing geometric parameters, significantly reducing required number of simulations, and accelerating the design process compared to conventional methods.

Language: Английский

Citations

1

Enhanced mixing in a novel microchannel equipped with a helical micromixer: Investigation on the hydrodynamic characteristics of water/butanol two-phase system DOI

Sobhan Farahani,

Salman Movahedirad, Mohammad Amin Sobati

et al.

Journal of the Taiwan Institute of Chemical Engineers, Journal Year: 2025, Volume and Issue: 170, P. 105985 - 105985

Published: Feb. 1, 2025

Language: Английский

Citations

1

Microfluidic Hydraulic Oscillators: A Comprehensive Review of Emerging Biochemical and Biomedical Applications DOI
Md. Ahasan Ahamed, Mahmudul Hasan, Md. Emamul Kabir

et al.

Analytica Chimica Acta, Journal Year: 2025, Volume and Issue: 1350, P. 343793 - 343793

Published: Feb. 13, 2025

Language: Английский

Citations

1

Quantitative analysis of mRNA-lipid nanoparticle stability in human plasma and serum by size-exclusion chromatography coupled with dual-angle light scattering DOI
Brian Liau, Li Zhang, Melgious Jin Yan Ang

et al.

Nanomedicine Nanotechnology Biology and Medicine, Journal Year: 2024, Volume and Issue: 58, P. 102745 - 102745

Published: March 16, 2024

Language: Английский

Citations

8

Convolutional neural network augmented soft-sensor for autonomous microfluidic production of uniform bubbles DOI
Owen Land, Warren D. Seider, Daeyeon Lee

et al.

Chemical Engineering Journal, Journal Year: 2024, Volume and Issue: 499, P. 156494 - 156494

Published: Oct. 9, 2024

Language: Английский

Citations

4

Recent advances in electrospray encapsulation of probiotics: influencing factors, natural polymers and emerging technologies DOI

Haifu Jia,

Yuanyuan Li,

Yueling Tian

et al.

Critical Reviews in Food Science and Nutrition, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 18

Published: Jan. 6, 2025

The probiotic food sector is rapidly growing due to increased consumer demand for nutritional supplements. However, ensuring viability within the harsh conditions of gastrointestinal tract remains a major challenge. While encapsulation promising solution enhance viability, most traditional methods have significant limitations. This review underscores significance adopting novel technologies, particularly electrospray (ES), which offers superior efficiency and versatility. It begins with an introduction principles classification ES, analyzes factors influencing properties ES microcapsules, reviews use natural polymers in ES-based encapsulation. Additionally, it discusses recent advancements this field, focusing on improvements equipment (e.g., coaxial emulsion ES) integration other technologies microfluidic ES-fluidized bed coating). Finally, highlights existing challenges explores future prospects evolving offering valuable insights advancing enhancing public health outcomes.

Language: Английский

Citations

0

Development and microfluidic testing of a new numerical algorithm and software for modeling immiscible fluid flows in digital core models DOI
А. А. Гаврилов, Д В Гузей, Andrey I. Pryazhnikov

et al.

Fuel, Journal Year: 2025, Volume and Issue: 386, P. 134253 - 134253

Published: Jan. 6, 2025

Language: Английский

Citations

0