The Application and Research Progress of Hydrogel Loading Stem Cells in Bone Regeneration DOI Creative Commons

Shenyu Zhao

MedScien, Journal Year: 2024, Volume and Issue: 1(7)

Published: June 6, 2024

Nowadays, osteogenesis technology is one of the hot topics in current orthopedic field. Globally, improving stability and efficiency bone regeneration has become a problem that society been studying. Due to its good tunability, compatibility, combination ability, hydrogel gradually applied technology. Stem cells can differentiate copy, have certain clinical potential treatment tissue. In recent years, many new types materials developed, some are expected be trials. Likewise, stem cell therapy also at forefront medical research today. Many characteristics make part them smoothly regeneration. this review, experimental data results cutting-edge developmental hydrogel-loading field collected, development application will summarized. The article contains nature, preparation, hydrogel; discusses effective role regeneration; combined with biological factor future technologies. focuses on different composite hydrogel. At same time, these hydrogels more efficient stable through characteristics. Therefore, review tells far-reaching impact technology, skeletal development, even organizational repair.

Language: Английский

Multifunctional hydrogel scaffolds based on polysaccharides and polymer matrices promote bone repair: A review DOI

Chang Bing Shen,

Yuanyuan Han, Huan Xiong

et al.

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: 294, P. 139418 - 139418

Published: Jan. 5, 2025

Language: Английский

Citations

1
Novel 3D printed TPMS scaffolds: microstructure, characteristics and applications in bone regeneration DOI Creative Commons
Jiaqi Ma, Yumeng Li,

Yujing Mi

et al.

Journal of Tissue Engineering, Journal Year: 2024, Volume and Issue: 15

Published: Jan. 1, 2024

Bone defect disease seriously endangers human health and affects beauty function. In the past five years, three dimension (3D) printed radially graded triply periodic minimal surface (TPMS) porous scaffold has become a new solution for repairing bone defects. This review discusses 3D printing technologies applications TPMS scaffolds. To this end, microstructural effects of scaffolds on regeneration were reviewed structural characteristics TPMS, which can promote regeneration, introduced. Finally, challenges prospects using to treat defects presented. is expected stimulate interest tissue engineers in provide reliable clinical treatment personalised

Language: Английский

Citations

8
Engineering injectable composite scaffolds for enhanced bone healing: Integration of stem cells, hydrogels, and microspheres DOI Creative Commons
Hongda Wang,

Junjin Li,

Haiwen Feng

et al.

Chemical Engineering Journal, Journal Year: 2025, Volume and Issue: unknown, P. 160593 - 160593

Published: Feb. 1, 2025

Language: Английский

Citations

0
Assessment of bone regeneration potential for a 6-bromoindirubin-3′-oxime (BIO) encapsulated chitosan based scaffold in a mouse critical sized bone defect model DOI
Celine J. Agnes, Ling Li, David Bertrand

et al.

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: 304, P. 140995 - 140995

Published: Feb. 12, 2025

Language: Английский

Citations

0
Multifunctional NIR-II Nanoplatform for Disrupting Biofilm and Promoting Infected Wound Healing DOI

Jinqiang Wu,

Xiao-Lei Huo, Jinjia Liu

et al.

Colloids and Surfaces B Biointerfaces, Journal Year: 2024, Volume and Issue: 245, P. 114330 - 114330

Published: Oct. 23, 2024

Language: Английский

Citations

2
In situ borneol-modified polyester with antibacterial adhesion and long-term fungal-repellent properties DOI

Zixu Xie,

Chen Chen, Xinyu Chen

et al.

Reactive and Functional Polymers, Journal Year: 2024, Volume and Issue: 202, P. 105993 - 105993

Published: June 22, 2024

Language: Английский

Citations

1
Bioactive Hydrogels Inspired by Laminin: An Emerging Biomaterial for Tissue Engineering Applications DOI Creative Commons
Sweta Mohanty, Sangita Roy

Macromolecular Bioscience, Journal Year: 2024, Volume and Issue: 24(11)

Published: Aug. 22, 2024

Abstract Tissue or organ damage due to severe injuries chronic diseases can adversely affect the quality of life. Current treatments rely on tissue transplantation which has limitations including unavailability donors, ethical issues, immune rejection after transplantations. These be addressed by regeneration involves development bioactive scaffolds closely mimicking extracellular matrix (ECM). One major components ECM is laminin protein supports several tissues associated with important organs. In this direction, peptide‐based hydrogels effectively mimic essential characteristics laminin. While reports have discussed structure laminin, potential laminin‐derived peptide as effective biomaterial for engineering applications yet discussed. context, current review focuses and its role an protein. Further, short in crucial properties proposed. The further highlights significance inspired – addressing numerous angiogenesis, neural, skeletal muscle, liver, adipose along a brief outlook future these laminin‐based hydrogels.

Language: Английский

Citations

1
In Situ Borneol-Modified Polyester with Antibacterial Adhesion and Long-Term Fungal-Repellent Properties DOI

Zixu Xie,

Chen Chen, Xinyu Chen

et al.

Published: Jan. 1, 2024

Polyester is widely utilized in biomedical, textile and food packaging fields, therefore imbuing it with antimicrobial properties would be a big advancement. In this paper, series of borneol-triazine polyesters (BTPs) different structures are synthesized by room temperature polycondensation. The structure composition BTPs systematically characterized 1H NMR, FTIR GPC. Antimicrobial experiments reveal that the ability to resist bacterial or fungal adhesion directly related polymer structure. When chain adopts rigid structure,they exhibit excellent anti-adhesive inhibitory performances against Gram-negative bacteria (Escherichia coli), Gram-positive (Staphylococcus aureus). Meanwhile, as-synthesized poses fungal-repelling effect on common strains (Aspergillus niger) for up 30 d. Further studies have shown stereochemical brought borneol key imparting effective BTPs. addition, non-leaching material low cellular cytotoxicity. Taking into consideration, provides potential strategy prepare new class polyester materials.

Language: Английский

Citations

0
Preliminary Evaluation of Poly-(Sorbitol-Co-Citrate Adipate) Properties for Application as Biomaterial DOI Open Access
A. Torres, Boutros Sarrouh, Renata Carolina Zanetti Lofrano

et al.

Published: April 4, 2024

This study evaluated the stability of Poly-(sorbitol-co-citrate adipate) with potential applica-tion in biomedical area. Thus, physical, chemical and microbiological this was investigated. First, alkaline phosphate buffer (pH 7.4) for 5 days. In aqueous solution, copolymer acidified medium indicating presence residual citric acid. moisture absorption test results obtained followed pH, reinforcing evaluation antimicrobial activity indicate that did not allow growth yeast Saccharomyces cerevisiae, as only source carbon. However, cell lysis phase due to restriction access nutrients culture medium, showed a loss mass its use by microorganism. it presented biodegradability property under extreme conditions culture.

Language: Английский

Citations

0
The Application and Research Progress of Hydrogel Loading Stem Cells in Bone Regeneration DOI Creative Commons

Shenyu Zhao

MedScien, Journal Year: 2024, Volume and Issue: 1(7)

Published: June 6, 2024

Nowadays, osteogenesis technology is one of the hot topics in current orthopedic field. Globally, improving stability and efficiency bone regeneration has become a problem that society been studying. Due to its good tunability, compatibility, combination ability, hydrogel gradually applied technology. Stem cells can differentiate copy, have certain clinical potential treatment tissue. In recent years, many new types materials developed, some are expected be trials. Likewise, stem cell therapy also at forefront medical research today. Many characteristics make part them smoothly regeneration. this review, experimental data results cutting-edge developmental hydrogel-loading field collected, development application will summarized. The article contains nature, preparation, hydrogel; discusses effective role regeneration; combined with biological factor future technologies. focuses on different composite hydrogel. At same time, these hydrogels more efficient stable through characteristics. Therefore, review tells far-reaching impact technology, skeletal development, even organizational repair.

Language: Английский

Citations

0