Photoredox/Nickel Dual-Catalysis-Enabled Regioselective Cyclization of Alkenes with Alkyl Chlorides DOI

Xuege Yang,

Lou Shi, Ruoyu Qin

et al.

Published: Jan. 1, 2023

A photoredox/nickel dual catalysis is presented for the construction of several kinds useful nitrogen-containing heterocycles. This protocol regioselective and features a broad substrate scope. It provides direct access to heterocycles by reacting alkyl chlorides with readily available activated unactivated alkenes. Moreover, this can be easily scalable gram-scale, it feasible use sunlight as light source. Mechanistic studies suggest that energy transfer pathway involved in catalytic process.

Language: Английский

Synthesis of Diverse 4‐Pyrrolin‐2‐ones by Electrochemically Induced Dehydrogenative Regioselective Cyclization of 3‐Aza‐1,5‐dienes and 1,3‐Dicarbonyl Compounds DOI
Xing Ji,

Run He,

Lou Shi

et al.

European Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: 27(11)

Published: Jan. 20, 2024

Abstract A practical and mild electrochemical dehydrogenative regioselective cyclization method has been established for the synthesis of 4‐pyrrolin‐2‐ones using 3‐aza‐1,5‐dienes 1,3‐dicarbonyl compounds as substrates. This protocol is catalyst‐free, metal‐free, does not require oxidizing agents. It exhibits wide substrate compatibility can be easily scaled up to gram scale.

Language: Английский

Citations

9
Photoredox/nickel dual-catalysis-enabled synthesis of N-heterocycles from alkyl chlorides and alkenes DOI

Xuege Yang,

Lou Shi, Ruoyu Qin

et al.

Molecular Catalysis, Journal Year: 2024, Volume and Issue: 553, P. 113806 - 113806

Published: Jan. 1, 2024

Language: Английский

Citations

6
Copper-Catalyzed [3 + 2] Annulation of O-Acyl Oximes with 4-Sulfonamidophenols for the Synthesis of 5-Sulfonamidoindoles and 2-Amido-5-sulfonamidobenzofuran-3(2H)-ones DOI

Zi-Jun Hu,

Wei Chen,

Xinyu Lyu

et al.

Organic Letters, Journal Year: 2024, Volume and Issue: 26(20), P. 4229 - 4234

Published: May 13, 2024

A copper-catalyzed [3 + 2] annulation of

Language: Английский

Citations

3
Copper-Catalyzed [3 + 2] Annulation of O-Acyl Oximes with p-Hydroquinones for the Synthesis of 5-Hydroxyindoles DOI

Hui-Peng Zhang,

Wei Chen,

Zi-Jun Hu

et al.

The Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 4, 2024

A copper-catalyzed [3 + 2] annulation of

Language: Английский

Citations

0
Photoredox/Nickel Dual-Catalysis-Enabled Regioselective Cyclization of Alkenes with Alkyl Chlorides DOI

Xuege Yang,

Lou Shi, Ruoyu Qin

et al.

Published: Jan. 1, 2023

A photoredox/nickel dual catalysis is presented for the construction of several kinds useful nitrogen-containing heterocycles. This protocol regioselective and features a broad substrate scope. It provides direct access to heterocycles by reacting alkyl chlorides with readily available activated unactivated alkenes. Moreover, this can be easily scalable gram-scale, it feasible use sunlight as light source. Mechanistic studies suggest that energy transfer pathway involved in catalytic process.

Language: Английский

Citations

0