Divergent synthesis of difluoromethylated indole-3-carbinols, bisindolylmethanes and indole-3-methanamines DOI

Yifei Qu,

Xiaojia Cai,

Yuzhuang Guan

et al.

Organic & Biomolecular Chemistry, Journal Year: 2023, Volume and Issue: 22(1), P. 90 - 94

Published: Nov. 24, 2023

A facile and straightforward method for the successful synthesis of difluoromethylated indole-3-carbinols, bisindolylmethanes indole-3-methanamines by a Friedel–Crafts reaction is developed.

Language: Английский

Rh(III)-Catalyzed, Redox-Neutral, C–H Multifluoroalkenylation of Benzamides DOI
Wen‐Hua Chen, Jun Xu, Jia‐Qiang Wu

et al.

Synthesis, Journal Year: 2024, Volume and Issue: 56(19), P. 3045 - 3053

Published: June 11, 2024

Abstract Fluorinated molecules are widely used in pharmaceutical and agrochemical industries. Multifluoroalkyl-containing compounds have attracted increasing attention for their unique ability to alter the activity of drugs bioactive molecules. Herein, we report an efficient Rh(III)-catalyzed, redox-neutral, C–H multifluoroalkenylation benzamides with multifluoroalkenes, which provides a versatile protocol accessing wide range multifluoroalkenylated arenes.

Language: Английский

Citations

0
Divergent synthesis of difluoromethylated indole-3-carbinols, bisindolylmethanes and indole-3-methanamines DOI

Yifei Qu,

Xiaojia Cai,

Yuzhuang Guan

et al.

Organic & Biomolecular Chemistry, Journal Year: 2023, Volume and Issue: 22(1), P. 90 - 94

Published: Nov. 24, 2023

A facile and straightforward method for the successful synthesis of difluoromethylated indole-3-carbinols, bisindolylmethanes indole-3-methanamines by a Friedel–Crafts reaction is developed.

Language: Английский

Citations

1