Chemical Communications, Journal Year: 2024, Volume and Issue: 60(38), P. 5050 - 5053
Published: Jan. 1, 2024
An unprecedented solvent-tuned electrochemical method for selective C(sp
Language: Английский
Chemical Communications, Journal Year: 2024, Volume and Issue: 60(38), P. 5050 - 5053
Published: Jan. 1, 2024
An unprecedented solvent-tuned electrochemical method for selective C(sp
Language: Английский
The Journal of Organic Chemistry, Journal Year: 2025, Volume and Issue: unknown
Published: Feb. 13, 2025
Herein, we report sodium iodide (NaI)-catalyzed decarboxylative C–H alkylation of azauracils with N-hydroxyphthalimide (NHPI) esters facilitated by visible light activation catalytic electron donor–acceptor (EDA) complexes. Control experiments and density functional theory calculations suggest that the coupling reaction proceeds via a transiently assembled EDA complex between NHPI ester NaI in N,N-dimethylacetamide solvent. This synthetic method efficiently applies to primary, secondary, tertiary under mild, photocatalyst-free, redox-neutral conditions, achieving high yields desired alkylated azauracils.
Language: Английский
Citations
2Chemical Communications, Journal Year: 2024, Volume and Issue: 60(21), P. 2958 - 2961
Published: Jan. 1, 2024
Visible-light-driven EDA complex-promoted ring-opening of cycloketone oxime esters to synthesise various 4-cyanoalkylated isoquinoline-1,3-diones with acryloylbenzamides was developed.
Language: Английский
Citations
10Organic & Biomolecular Chemistry, Journal Year: 2024, Volume and Issue: 22(5), P. 965 - 969
Published: Jan. 1, 2024
A visible-light-induced, electron donor–acceptor (EDA) complex-enabled decarboxylative cascade reaction of acryloylbenzamides with alkyl N -hydroxyphthalimide esters by NaI/PPh 3 catalysis was developed.
Language: Английский
Citations
5Organic & Biomolecular Chemistry, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 1, 2025
A novel, efficient and sustainable visible-light–mediated methodology for the construction of pyrazolo[4,3- d ]pyrimidin-7(6 H )-ones from easily available starting materials has been developed.
Language: Английский
Citations
0The Journal of Organic Chemistry, Journal Year: 2025, Volume and Issue: unknown
Published: April 22, 2025
A visible-light-driven intermolecular tandem α-amidotrifluoroethylation/cyclization of enaminones using a previously unreported N-trifluoroethylaminopyridinium salt was achieved in the absence transition metal catalysts or bases. Notable features this synthetic method include mild conditions, high selectivity, excellent functional group compatibility, and satisfactory yields. Preliminary mechanistic studies indicate that reaction proceeds via radical pathway, involving an situ generated N-trifluoroethyl radical, followed by 1,2-H shift.
Language: Английский
Citations
0Chemical Communications, Journal Year: 2024, Volume and Issue: 60(38), P. 5050 - 5053
Published: Jan. 1, 2024
An unprecedented solvent-tuned electrochemical method for selective C(sp
Language: Английский
Citations
3