Metal‐Free Direct Synthesis of N‐Sulfonyl Amidines from Thioamides and Electron Deficient N‐Sulfonylamides DOI
Jigarkumar K. Vankar, Srinu Tothadi, Guddeangadi N. Gururaja

et al.

European Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: 27(45)

Published: Aug. 29, 2024

Abstract A metal‐free, efficient synthesis of N ‐sulfonyl amidines has been demonstrated from easily accessible thioamides and electron‐deficient sulfonyl amides. The amidation reaction is facile at room temperature with low amide loading. illustrated various amides broad substrate scope. utility amidine validated late‐stage drug functionalization.

Language: Английский

1,1,1,3,3,3-Hexafluoro-2-propanol (HFIP)-promoted regiospecific 1,6-hydroarylation of para-quinone methides with N-heteroarenes: Synthesis of unsymmetrical triarylmethanes DOI
Haiyan Xu,

C. K. LIANG,

Junyu Zhu

et al.

Tetrahedron, Journal Year: 2024, Volume and Issue: 158, P. 133982 - 133982

Published: April 7, 2024

Language: Английский

Citations

2
Metal‐Free Direct Synthesis of N‐Sulfonyl Amidines from Thioamides and Electron Deficient N‐Sulfonylamides DOI
Jigarkumar K. Vankar, Srinu Tothadi, Guddeangadi N. Gururaja

et al.

European Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: 27(45)

Published: Aug. 29, 2024

Abstract A metal‐free, efficient synthesis of N ‐sulfonyl amidines has been demonstrated from easily accessible thioamides and electron‐deficient sulfonyl amides. The amidation reaction is facile at room temperature with low amide loading. illustrated various amides broad substrate scope. utility amidine validated late‐stage drug functionalization.

Language: Английский

Citations

0