Chemical Engineering Journal, Journal Year: 2025, Volume and Issue: 514, P. 163228 - 163228
Published: April 30, 2025
Language: Английский
Applied Surface Science, Journal Year: 2025, Volume and Issue: unknown, P. 162467 - 162467
Published: Jan. 1, 2025
Language: Английский
Citations
2
SusMat, Journal Year: 2024, Volume and Issue: unknown
Published: Nov. 27, 2024
ABSTRACT Flexible sensors exhibit the properties of excellent shape adaptability and deformation ability, which have been applied for environmental monitoring, medical diagnostics, food safety, smart systems, human–computer interaction. Cellulose‐based hydrogels are ideal materials fabrication flexible due to their unique three‐dimensional structure, renewability, ease processing, biodegradability, modifiability, good mechanical properties. This paper comprehensively reviews recent advances cellulose‐based in construction sensor applications. The characteristics, mechanisms, advantages prepared by physical cross‐linking, chemical cross‐linking respectively analyzed summarized detail. focus then turns research development hydrogel sensors, including sensing (pressure/strain, humidity/temperature, optical sensing), (chromium, copper, mercury ion sensing, toxic gas nitrite biosensing (glucose, antibody, cellular sensing). Additionally, limitations along with key challenges future directions, discussed. It is anticipated that this review will furnish invaluable insight advancement novel green, facilitate integration as a fundamental component multifunctional technologies, thereby expediting design innovative near future.
Language: Английский
Citations
15
Journal of Biomaterials Science Polymer Edition, Journal Year: 2025, Volume and Issue: unknown, P. 1 - 27
Published: Jan. 9, 2025
Molecular Dynamics (MD) simulations are now widely utilized in pharmaceutical nanotechnology to gain deeper understanding of nanoscale processes imperative drug design. This review has also detailed how MD simulation can be employed the study drug-nanocarrier interactions, controlling release chemical compounds from delivery systems and increasing solubility bioavailability nanocarriers. Furthermore, contributes examining systems, measuring toxic effects, determining biocompatibility nanomedical systems. With incorporation artificial intelligence use hybrid gone a step ahead model other niches biology that make tremendous opening develop highly selective nanomedications. Nevertheless, with well-known issues such as computational constraints discrepancy between silico experiment results, remains work progress, considerable promise for replacing or supplementing existing approaches development precision medicine nanomedicine, continued progression healthcare hopeful.
Language: Английский
Citations
1
Advanced Functional Materials, Journal Year: 2025, Volume and Issue: unknown
Published: Feb. 9, 2025
Abstract Anti‐tumor theranostic radionuclide nanosystems have gained significant attention as an emerging therapeutic strategy. This review systematically elucidates the concept and recent advances of anti‐tumor nanotheranostic systems with radionuclides, a focus on design nanocarriers, precise selection their advantages limitations in clinical translation. also explores integration imaging various treatment modalities, including photodynamic therapy, photothermal sonodynamic immunotherapy. Furthermore, combination therapy fluorescence magnetic resonance technologies, which broadens application nanotheranostics, is discussed. Finally, outlooks future development nanotheranostics radionuclides proposes key research focus.
Language: Английский
Citations
1
BioNanoScience, Journal Year: 2025, Volume and Issue: 15(2)
Published: March 22, 2025
Language: Английский
Citations
1
Published: Feb. 1, 2025
Language: Английский
Citations
0
Applied Organometallic Chemistry, Journal Year: 2025, Volume and Issue: 39(4)
Published: March 3, 2025
ABSTRACT Cancer is a significant global public health concern, being the second leading cause of mortality, accounting for one in six cases worldwide. Researchers have employed various approaches cancer treatment, with nanobiotechnology emerging as standout technique developing anticancer agents. This study assessed activity chitosan (CS)‐coated gold nanoparticles (AuNPs) and combination AuNPs–papain (Pap)–folic acid (FA) nanomaterial platforms against Michigan Foundation‐7 (MCF‐7) cell lines. A range methods, including ultraviolet–visible (UV–Vis), Fourier transform infrared (FTIR), scanning electron microscopy (SEM), transmission (TEM), X‐ray diffraction (XRD), energy‐dispersive spectroscopy (EDS), zeta potential, were used to characterize prepared nanomaterials. AuNPs AuNPs–Pap–FA exhibited UV–Vis absorption at 525 558 nm, respectively. In XRD test, peaks found 32°, 39°, 45°, 65°, 78.5°, AuNPs–CS–Pap–FA identified 29, 37°, 78.5°. SEM revealed irregularly dispensed oval shapes AuNPs. TEM images confirmed shape before after coating Pap FA. The mean diameter was 15 AuNPs–CS–Pap–FA, it 22.5 nm. Acridine orange–ethidium bromide (AO/EB) staining, flow cytometry assay, 2,2‐diphenyl‐1‐picrylhydrazyl (DPPH), vitro hemolysis assays conducted. maximum scavenging observed reaching up 90%. hemolytic rate low concentrations (3.12, 6.25, 12.5 μg mL −1 ) within permissible levels. concentration 100 reduced viability MCF‐7 cells 10% when compared nontreated cells. highest expression caspase‐8 achieved treating line AuNPs–CS–Pap–FA. nanopreparation remarkable holds promise potential candidate further development towards clinical applications an agent.
Language: Английский
Citations
0
Journal of Controlled Release, Journal Year: 2025, Volume and Issue: unknown, P. 113667 - 113667
Published: March 1, 2025
Language: Английский
Citations
0
ACS Nano, Journal Year: 2025, Volume and Issue: unknown
Published: April 23, 2025
Epilepsy is a common neurological disorder characterized by significant rate of disability. Accurate early diagnosis and precise localization the epileptogenic zone are essential for timely intervention, seizure prevention, personalized treatment. However, over 30% patients with epilepsy exhibit negative results on electroencephalography magnetic resonance imaging (MRI), which can lead to misdiagnosis subsequent delays in Consequently, enhancing diagnostic methodologies imperative effective management. The integration nanomaterials biomedicine has led development tools epilepsy. Key advancements include nanomaterial-enhanced neural electrodes, contrast agents, biochemical sensors. Nanomaterials improve quality electrophysiological signals broaden detection range electrodes. In imaging, functionalized nanoparticles enhance MRI sensitivity, facilitating zone. NIR-II nanoprobes enable tracking seizure-related biomarkers deep tissue penetration. Furthermore, sensitivity sensors detecting biomarkers, crucial detection. These significantly increase specificity. challenges remain, particularly regarding biosafety, control, scalability fabrication processes. Overcoming these obstacles successful clinical translation. Artificial-intelligence-based big data analytics facilitate screening specific properties. This approach may help address current limitations both effectiveness safety. review explores application epilepsy, objective inspiring innovative ideas strategies effectiveness.
Language: Английский
Citations
0
Chemical Engineering Journal, Journal Year: 2025, Volume and Issue: 514, P. 163228 - 163228
Published: April 30, 2025
Language: Английский
Citations
0