High-Density Lipoprotein Nanoparticles Loaded with Silybin for Therapy of Drug-Induced Liver Injury DOI
Yuxin Zhao, Kai Liu, Chunmei Yan

et al.

ACS Applied Nano Materials, Journal Year: 2025, Volume and Issue: unknown

Published: June 4, 2025

Language: Английский

Artichoke water extract protects against Lead-induced hepatotoxicity by activating Nrf2 signaling and inhibiting NLRP3/caspase-1/GSDMD-mediated pyroptosis DOI Creative Commons
Aihua Deng,

Mengyuan Yi,

Yun Wang

et al.

Journal of Ethnopharmacology, Journal Year: 2025, Volume and Issue: unknown, P. 119654 - 119654

Published: March 1, 2025

Language: Английский

Citations

0
Cynarin protects against seizures and neuronal death in a rat model of kainic acid-induced seizures DOI
Cheng‐Wei Lu, Tzu‐Yu Lin,

Wei Pan

et al.

Food & Function, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

The potential therapeutic value of cynarin, a phenolic compound derived from artichoke, in treating epilepsy has not yet been reported.

Language: Английский

Citations

0
Functional foods and bioactive compounds: a comprehensive review on their role in mitigating drug-induced liver injury DOI Creative Commons
Jinmin Zhao, Weiyi Zhao, Meng Zhao

et al.

Frontiers in Nutrition, Journal Year: 2025, Volume and Issue: 11

Published: May 21, 2025

Drug-induced liver injury (DILI) has become a serious public health issue worldwide. Many drugs (chemotherapy drugs, fever-reducing medications, nonsteroidal anti-inflammatory immunosuppressants, antibiotics, antivirals, and antineoplastic etc.) may cause damage potentially lead to acute failure (ALF). There is an urgent need develop effective treatment programs for DILI. Here, the epidemiology, pathogenesis molecular mechanisms of DILI, reported functional foods dietary bioactive constituents, such as phenols, flavonoids, glycosides, terpenes, carotenoids, isolated from food (legumes, nuts, grains, fruits, spices vegetables, their protective against DILI are summarized classified. Research shows that antipyretic analgesic (such acetaminophen) most common causes drug-induced (DILI). Compounds derived food, particularly have been extensively studied ability alleviate caused by acetaminophen. They exert significant hepatoprotective effects preventing mitochondrial dysfunction oxidative stress, well inhibiting inflammation. However, reducing toxicity food-derived compounds improving solubility bioavailability in remain current future challenges address. Future research on application anti-DILI also needed. Overall, this review provide insights into potential use

Language: Английский

Citations

0
High-Density Lipoprotein Nanoparticles Loaded with Silybin for Therapy of Drug-Induced Liver Injury DOI
Yuxin Zhao, Kai Liu, Chunmei Yan

et al.

ACS Applied Nano Materials, Journal Year: 2025, Volume and Issue: unknown

Published: June 4, 2025

Language: Английский

Citations

0