Dearomative Cyclization/Spirocyclization via Electrochemical Reductive Hydroarylation of Nonactivated Arenes DOI
Yi Wu, Xian‐Li Ma, Fang-Yao Li

et al.

Organic Letters, Journal Year: 2024, Volume and Issue: 26(42), P. 8993 - 8998

Published: Oct. 14, 2024

An electrochemical cyclization/spirocyclization hydroarylation via reductive dearomatization of a series nonactivated arenes including

Language: Английский

Practical Electrochemical Hydrogenation of Nitriles at Nickel Foam Cathode DOI Creative Commons

Rok Narobe,

Marcel Nicolas Perner,

María de Jesús Gálvez‐Vázquez

et al.

Green Chemistry, Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 1, 2024

We report a scalable hydrogenation method for nitriles based on cost-effective materials in very simple two-electrode setup under galvanostatic conditions. All components are commercially and readily available. The is easy to conduct applicable variety of nitrile substrates, leading exclusively primary amine products yields up 89% using an work-up protocol. Importantly, this transferable from the milligram scale batch-type screening cells multi-gram flow-type electrolyser. transfer flow electrolysis enabled us achieve notable 20 g day

Language: Английский

Citations

3
Electrochemically promoted selenocyclization for the synthesis of organoselenyl isoxazoles DOI
Nan Sun, Zhi Qiao,

Jiamin Li

et al.

Green Chemistry, Journal Year: 2024, Volume and Issue: 26(19), P. 10240 - 10246

Published: Jan. 1, 2024

Herein, we report a general and sustainable electrochemically promoted oxidative selenocyclization protocol for the synthesis of organoselenyl isoxazoles from 2-alkyn-1-one O -methyloximes diorganyl diselenides.

Language: Английский

Citations

2
De novo synthesis of 6-6-5 fused-systems through electrochemical decarboxylation and radical domino additions DOI

Chengcheng Yuan,

Guanru Liu,

Wenjing Guan

et al.

Green Chemistry, Journal Year: 2024, Volume and Issue: 26(19), P. 10308 - 10313

Published: Jan. 1, 2024

An oxidant and quaternary ammonium salt-free electrosynthesis of 6-6-5 fused systems was developed with excellent atom step economy.

Language: Английский

Citations

1
Defluorinative Haloalkylation of Unactivated Alkenes Enabled by Dual Photoredox and Copper Catalysis DOI
Shiyu Li,

Xinguang Li,

Kui-Kui Zhao

et al.

The Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: 89(18), P. 13518 - 13529

Published: Sept. 10, 2024

A three-component defluorinative haloalkylation of alkenes with trifluoromethyl compounds and TBAX (X = Cl, Br) via dual photoredox/copper catalysis is reported. The mild conditions are compatible a wide array activated aromatics bearing diverse substituents, various nonactivated terminal internal alkenes, enabling straightforward access to synthetically valuable γ-gem-difluoroalkyl halides high efficiency. Mechanistic studies indicate that the [Cu] complexes not only serve as XAT catalysts but also facilitate SET reduction groups by photocatalysts. Additionally, resulting alkyl halide products can versatile conversion intermediates for synthesis range compounds.

Language: Английский

Citations

1
Dearomative Cyclization/Spirocyclization via Electrochemical Reductive Hydroarylation of Nonactivated Arenes DOI
Yi Wu, Xian‐Li Ma, Fang-Yao Li

et al.

Organic Letters, Journal Year: 2024, Volume and Issue: 26(42), P. 8993 - 8998

Published: Oct. 14, 2024

An electrochemical cyclization/spirocyclization hydroarylation via reductive dearomatization of a series nonactivated arenes including

Language: Английский

Citations

0