3D-printed microfluidic and millifluidic devices for cell culture and mechanotransduction studies: A review DOI
Juan G. Santiago, Olga M. Rodríguez Martínez, P.A. Sundaram

et al.

Journal of Micromanufacturing, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 28, 2024

The practice of conventional cell culture techniques affects the quality biological research in mechanobiology by not replicating cell’s microenvironment adequately. Microfluidic devices resembling 3D vivo offer viable alternatives for studies and other applications including screening, separation, point-of-care diagnostics. This review highlights recent advances additive manufacturing (AM) to fabricate microfluidic millifluidic through fast design iterations cost reduction compared with device manufacturing. Key AM technologies such as fused deposition modeling (FDM), stereolithography apparatus (SLA), digital light processing (DLP) have allowed direct manufacture complex master molds sacrificial structures using multiple material components. Currently, available printed precise fabrication milli- devices, essential mimicking cellular microenvironment, while economically reducing production costs eliminating expensive clean-room environments waste are highlighted.

Language: Английский

A review of the recent achievements and future trends on 3D printed microfluidic devices for bioanalytical applications DOI
Lucas C. Duarte, Federico Figueredo, C Chagas

et al.

Analytica Chimica Acta, Journal Year: 2024, Volume and Issue: 1299, P. 342429 - 342429

Published: Feb. 28, 2024

Language: Английский

Citations

14

Powder Bed Fusion 3D Printing in Precision Manufacturing for Biomedical Applications: A Comprehensive Review DOI Open Access

R. Nekin Joshua,

S. Aravind Raj, Mohamed Thariq Hameed Sultan

et al.

Materials, Journal Year: 2024, Volume and Issue: 17(3), P. 769 - 769

Published: Feb. 5, 2024

Precision manufacturing requirements are the key to ensuring quality and reliability of biomedical implants. The powder bed fusion (PBF) technique offers a promising solution, enabling creation complex, patient-specific implants with high degree precision. This technology is revolutionizing industry, paving way for new era personalized medicine. review explores details 3D printing its application in field. It begins an introduction 3D-printing various classifications. Later, it analyzes numerous fields which has been successfully deployed where precision components required, including fabrication scaffolds tissue engineering. also discusses potential advantages limitations using terms precision, customization, cost effectiveness. In addition, highlights current challenges prospects technology. work valuable insights researchers engaged field, aiming contribute advancement context applications.

Language: Английский

Citations

13

Recent advances in 3D-printing-based organ-on-a-chip DOI Creative Commons

Xinkun Wu,

Wenwan Shi,

Xiaojiang Liu

et al.

Deleted Journal, Journal Year: 2024, Volume and Issue: 1(1), P. 100003 - 100003

Published: March 21, 2024

Organ-on-a-chip (OOC) facilitates precise manipulation of fluids in microfluidic chips and simulation the physiological, chemical, mechanical characteristics tissues, thus providing a promising tool for vitro drug screening physiological modeling. In recent decades, this technology has advanced rapidly because development various three-dimensional (3D) printing techniques. 3D can not only fabricate using materials such as resins polydimethylsiloxane but also construct biomimetic tissues bioinks cell-loaded hydrogels. review, advances 3D-printing-based OOC are systematically summarized based on used direct or indirect OOC, techniques construction applications models heart, blood vessels, intestines, liver, kidney. addition, future perspectives challenges area envisioned to inspire researchers employ accelerate development.

Language: Английский

Citations

12

Vat Photopolymerization Based Digital Light Processing 3D Printing Hydrogels in Biomedical Fields: Key Parameters and Perspective DOI
Zhe Lü,

Weizi Gao,

Fukang Liu

et al.

Additive manufacturing, Journal Year: 2024, Volume and Issue: unknown, P. 104443 - 104443

Published: Sept. 1, 2024

Language: Английский

Citations

12

Lithography-based 3D printing of hydrogels DOI
Abhishek P. Dhand, Matthew D. Davidson, Jason A. Burdick

et al.

Nature Reviews Bioengineering, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 16, 2024

Language: Английский

Citations

10

Direct laser writing-enabled 3D printing strategies for microfluidic applications DOI Creative Commons
Olivia M. Young, Xin Xu, Sunandita Sarker

et al.

Lab on a Chip, Journal Year: 2024, Volume and Issue: 24(9), P. 2371 - 2396

Published: Jan. 1, 2024

Over the past decade, additive manufacturing-or "three-dimensional (3D) printing"-has attracted increasing attention in

Language: Английский

Citations

9

Recent advances in Organ-on-a-Chip models: How precision engineering integrates cutting edge technologies in fabrication and characterization DOI
Sorour Sadeghzade, Mohammad Hosseini Hooshiar, Hossein Akbari

et al.

Applied Materials Today, Journal Year: 2024, Volume and Issue: 38, P. 102231 - 102231

Published: May 14, 2024

Language: Английский

Citations

9

Microsensor systems for cell metabolism – from 2D culture to organ-on-chip (2019–2024) DOI Creative Commons
Johannes Dornhof, Jochen Kieninger, Stefan J. Rupitsch

et al.

Lab on a Chip, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

We review the latest developments in microsensor systems for monitoring metabolism of cell cultures and organs-on-chip, including sensor principles, requirements, performance, notable achievements, trends microfabrication.

Language: Английский

Citations

1

Advancements in 3D Printing Technologies for Personalized Treatment of Osteonecrosis of the Femoral Head DOI Creative Commons
Tingting Chen,

Lincong Luo,

Jiaying Li

et al.

Materials Today Bio, Journal Year: 2025, Volume and Issue: 31, P. 101531 - 101531

Published: Feb. 5, 2025

Three-dimensional (3D) printing technology has shown significant promise in the medical field, particularly orthopedics, prosthetics, tissue engineering, and pharmaceutical preparations. This review focuses on innovative application of 3D addressing challenges osteonecrosis femoral head (ONFH). Unlike traditional hip replacement surgery, which is often suboptimal for younger patients, offers precise localization necrotic areas ability to create personalized implants. By integrating advanced biomaterials, this a promising strategy approach early hip-preserving treatments. Additionally, 3D-printed bone engineering scaffolds can mimic natural environment, promoting regeneration vascularization. In future, potential extends combining with artificial intelligence optimizing treatment plans, developing materials enhanced bioactivity compatibility, translating these innovations from laboratory clinical practice. demonstrates how uniquely addresses critical ONFH treatment, including insufficient vascularization, poor mechanical stability, limited long-term success conventional therapies. introducing gradient porous scaffolds, bioactive material coatings, AI-assisted design, work outlines novel strategies improve interventions. These advancements not only enhance efficacy but also pave way findings into applications.

Language: Английский

Citations

1

Vibration-assisted vat photopolymerization for pixelated-aliasing-free surface fabrication DOI Creative Commons
Xu Han,

Renzhi Hu,

Shuai Chen

et al.

International Journal of Extreme Manufacturing, Journal Year: 2024, Volume and Issue: 6(3), P. 035004 - 035004

Published: Feb. 28, 2024

Highlights Vibration of the light source enhances both surface and contour smoothness in vat photopolymerization processes. Low-frequency mask screen vibration ensures a uniform intensity distribution. Subpixel amplitude mitigates pixelated, zig-zag contours. Dimensional geometrical errors are maintained within single pixel’s size. Vibration-assisted image projection shows promise for 3D printing optics.

Language: Английский

Citations

6