ChemBioChem,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Nov. 14, 2024
Abstract
Covalent
organic
frameworks
(COFs)
have
emerged
as
a
distinguished
class
of
porous
materials.
Owing
to
their
ability
be
constructed
through
covalent
bonds
involving
light
elements,
such
hydrogen,
boron,
carbon,
nitrogen,
and
oxygen,
COFs
offer
greater
stability
lower
cytotoxicity
than
metal–organic
do,
addressing
critical
limitations
in
vivo
applications.
Their
unique
attributes,
high
surface
area,
customizable
pore
sizes,
versatile
functionalities,
make
them
ideal
for
various
biomedical
This
review
aims
provide
an
overview
the
recent
advancements
modern
uses.
First,
variety
methods
synthesis
are
outlined,
which
ensures
suitability
medical
use.
Next,
we
delve
into
innovative
applications,
emphasizing
roles
disease
diagnosis
therapies.
Finally,
challenges,
clinical
translation,
biocompatibility,
controlled
drug
release,
critically
discussed,
providing
comprehensive
insight
potential
revolutionizing
technologies.
Overall,
this
offers
COFs’
capabilities
future
prospects
enhancing
Journal of Agricultural and Food Chemistry,
Journal Year:
2025,
Volume and Issue:
73(9), P. 4982 - 4997
Published: Feb. 21, 2025
In
food
safety,
detecting
pesticide
residues
from
environmental
exposure
is
garnering
increasing
global
attention.
Therefore,
it
crucial
to
develop
rapid
and
straightforward
detection
methods
for
residues.
comparison
the
limitations
of
traditional
techniques,
fluorescent
probes
have
become
ideal
tools
in
due
their
superior
non-destructive
real-time
monitoring
capabilities.
this
work,
first,
types
pesticides
commonly
found
fundamental
principles
underlying
probe
materials
are
introduced.
Second,
characteristics,
applications,
advantages,
prevalent
residue
evaluated.
Finally,
significance
within
context
safety
developmental
potential
field
summarized
discussed,
aiming
provide
a
valuable
reference
developing
new
future
research
directions.
ACS Nano,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Jan. 13, 2025
The
synthesis
of
covalent
organic
frameworks
(COFs)
with
excellent
luminescent
properties
and
their
effective
application
in
the
field
bionic
sensing
remain
a
formidable
challenge.
Herein,
series
COFs
different
numbers
hydroxyl
groups
are
successfully
synthesized,
number
on
benzene-1,3,5-tricarbaldehyde
(BTA)
linker
influences
final
COFs.
COF
(HHBTA-OH)
prepared
hydrazine
hydrate
(HH)
BTA
containing
one
group
as
ligands
exhibits
best
fluorescent
performance.
MA@HHBTA-OH
is
formed
by
reaction
HHBTA-OH
meldrum's
acid
(MA)
has
its
extremely
high
hydrophilicity,
dispersibility,
strong
red
fluorescence,
which
can
imitate
human
gustatory
system
to
detect
bitter
substances.
was
combined
agarose
(AG)
construct
MA@HHBTA-OH@AG
film
for
assessing
food
freshness.
In
addition,
an
acoustic
MA@HHBTA-OH@MF
sensor
fabricated
integrating
melamine
foam
(MF)
through
hydrogen
bond.
functions
like
eardrum
recognizes
sound
pressure
waves
mechanical
summary,
biomimetic
sensors
based
were
constructed,
monitor
auditory,
gustatory,
olfactory
information
achieve
multimode
perception
sound,
substances,
Advanced Optical Materials,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Feb. 6, 2025
Abstract
In
order
to
inhibit
non‐radiative
decay
pathways
of
covalent‐organic
frameworks
(COFs),
a
strategy
is
proposed
block
intralayer
conjugation
and
interlayer
π–π
stacking
by
using
flexible
aggregation‐induced
emission
(AIE)
building
blocks
(4′,4′′′,4′′′′′,4′′′′′′′‐(1,2‐ethenediylidene)
tetrakis[1,1′‐biphenyl]‐4‐carbaldehyde
(TFBE))
connected
weakly
conjugated
linker.
By
the
TFBE
as
changing
flexibility
linker,
TFBE‐COFs
with
different
luminescence
properties
are
obtained.
Experimental
theoretical
results
show
that
these
have
high
crystallinity
large
layer
spacing,
among
which
photoluminescence
quantum
yield
hydrazone
(Hz)‐COF
TFBE‐ODH
(oxalyl
dihydrazide
(ODH))
in
solid
state
reaches
26.28%,
superior
most
COFs
reported
so
far.
The
excellent
attributed
non‐planar
geometry
TFBE,
inhibits
quenching.
Moreover,
π‐electron
delocalization‐induced
leaps
suppressed
further
enhances
TFBE‐COFs.
Hz‐COF
exhibits
sensing
performance
for
trace
tetracycline,
detection
limit
0.15
µ
m
.
addition,
white
light‐emitting
diodes
coated
manufactured
achieve
high‐quality
light
emission.
This
study
provides
new
design
application
high‐emission
COFs.
Bioconjugate Chemistry,
Journal Year:
2025,
Volume and Issue:
unknown
Published: April 1, 2025
Fluorescence
imaging
technology
is
playing
increasing
roles
in
modern
personalized
and
precision
medicine.
Thanks
to
their
excellent
photophysical
properties,
organic
luminogens
featuring
aggregation-induced
emission
(AIE)
characteristics
(AIEgens)
have
attracted
considerable
attention
over
the
past
two
decades.
Because
of
superior
biocompatibility,
ease
processing
functionalization,
water
solubility,
high
responsiveness,
exceptional
signal-to-noise
ratio
(SNR)
for
biotargets,
AIE
bioconjugates,
formed
by
covalently
linking
AIEgens
with
biomolecules,
emerged
as
an
ideal
candidate
bioapplications.
In
this
review,
we
summarize
progress
preparation,
application
bioconjugates
last
five
years.
Moreover,
challenges
opportunities
are
also
briefly
discussed.
