I2-catalyzed tandem sp3 C–H oxidation and annulation of aryl methyl ketones with amidoximes for the synthesis of 5-aroyl-1,2,4-oxadiazoles DOI

Shiva Kumar Punna,

Mariyaraj Arockiaraj,

Venkatachalam Rajeshkumar

et al.

Organic & Biomolecular Chemistry, Journal Year: 2024, Volume and Issue: 22(36), P. 7478 - 7484

Published: Jan. 1, 2024

A metal-free, iodine-catalyzed protocol for the synthesis of biologically significant 5-aroyl 1,2,4-oxadiazole scaffolds has been developed using aryl methyl ketones and amidoximes.

Language: Английский

Pseudo‐Multicomponent Reactions of Lawsone: Synthetic Strategies of Bis‐Lawsone DOI Open Access
Swadhin Swaraj Acharya,

Dibyaranjan Samantaray,

Chipuru Sibakrishna

et al.

ChemistrySelect, Journal Year: 2025, Volume and Issue: 10(1)

Published: Jan. 1, 2025

Abstract 1,4‐Naphthoquinones (1,4‐NQs) are an important class of molecules with diverse pharmaceutical applications. Lawsone, a naturally occurring molecule range bioactivities, falls in the 1,4‐NQs. It possesses 1,3‐dicarbonyl functionality, which has been utilized synthesis bis‐lawsones reaction aldehydes. In this review we have discussed notable developments bis‐lawsone from 2009 to 2023. Also, highlights limitations and future perspectives area.

Language: Английский

Citations

1
Arylglyoxal-based multicomponent synthesis of C-3 functionalized imidazoheterocycles DOI
Swadhin Swaraj Acharya,

Rahul Kumar Sahoo,

Pralina Mohanty

et al.

Chemical Papers, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 10, 2024

Language: Английский

Citations

4
One-Pot Multicomponent Synthesis of Fully Substituted 1,3-Thiazoles Appended with Naturally Occurring Lawsone DOI
Swadhin Swaraj Acharya,

Bisal Kumar Guin,

Bibhuti Bhusan Parida

et al.

The Journal of Organic Chemistry, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 6, 2025

Lawsone is a popular bioactive natural product. 1,3-Thiazoles are also widely distributed in many products, FDA-approved drugs, and functional materials. We report herein the first synthesis of naturally occurring lawsone-linked fully substituted 1,3-thiazoles one-pot multicomponent reaction (MCR) arylglyoxals, lawsone, thiobenzamides acetic acid at 90 °C, affording lawsone-1,3-thiazole hybrids excellent yields short times. The advantages present method include facile, robust, easy access to medicinally relevant diverse array hybrids, isolation product by filtration, thereby avoiding column-chromatographic purifications, time, metal- catalyst-free gram-scale synthesis.

Language: Английский

Citations

0
Recyclable LaF3·Pd nanocatalyst in Suzuki coupling: green synthesis of biaryls from haloarenes and phenylboronic acids DOI Creative Commons

Smitabala Panda,

Sagarika Patra,

Swadhin Swaraj Acharya

et al.

RSC Advances, Journal Year: 2024, Volume and Issue: 14(30), P. 21269 - 21276

Published: Jan. 1, 2024

A green and sustainable approach has been developed using a recyclable reusable LaF 3 ·Pd nanocatalyst. This catalyst applied in the synthesis of biaryls good to excellent yields via Suzuki coupling aqueous medium.

Language: Английский

Citations

3
Synthetic Routes to Access Dicarbonylated Aryls and Heteroaryls DOI
Swadhin Swaraj Acharya, Bibhuti Bhusan Parida

Organic & Biomolecular Chemistry, Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 1, 2024

The regioselective 1,2-dicarbonylation of aryls and heteroaryls offers access to functionalized dicarbonylated heteroaryls, which opens pharmaceuticals bioactive molecules with diverse synthetic utility.

Language: Английский

Citations

2
Iodine-promoted sequential C(sp3)–H oxidation and cyclization of aryl methyl ketones with 2-(2-aminophenyl)quinazolin-4(3H)-ones DOI

Mariyaraj Arockiaraj,

Venkatachalam Rajeshkumar

Organic & Biomolecular Chemistry, Journal Year: 2024, Volume and Issue: 22(34), P. 7052 - 7058

Published: Jan. 1, 2024

An I

Language: Английский

Citations

1
I2-catalyzed tandem sp3 C–H oxidation and annulation of aryl methyl ketones with amidoximes for the synthesis of 5-aroyl-1,2,4-oxadiazoles DOI

Shiva Kumar Punna,

Mariyaraj Arockiaraj,

Venkatachalam Rajeshkumar

et al.

Organic & Biomolecular Chemistry, Journal Year: 2024, Volume and Issue: 22(36), P. 7478 - 7484

Published: Jan. 1, 2024

A metal-free, iodine-catalyzed protocol for the synthesis of biologically significant 5-aroyl 1,2,4-oxadiazole scaffolds has been developed using aryl methyl ketones and amidoximes.

Language: Английский

Citations

0