Cu(Ii)-Catalyzed Efficient Construction of 1,3-Naphthoxazines from 2-Naphthols, Amidines and N, N-Dimethylethanolamine DOI
Jinqiang Kuang,

Meiqi Geng,

Maozhong Miao

et al.

Published: Jan. 1, 2023

Herein, we report a Cu(II)-catalyzed multi-component reaction for the facile synthesis of 1,3-naphthoxazines from amidines and ortho-quinone methides, which are in situ-generated 2-naphthols N, N-dimethylaminoethanol (DMEA). DMEA acts as unique efficient C1 synthon well solvent. A variety with diverse functional groups were provided moderate to excellent yields.

Language: Английский

Efficient access to spiro[quinazoline-thiophen](thi)ones via acetic acid mediated [3 + 2] annulation of quinazolin(thi)one enamines with dithianediol DOI

Jingxi Fang,

Zhentao Pan,

Yingbo Rao

et al.

Tetrahedron Letters, Journal Year: 2024, Volume and Issue: 138, P. 154965 - 154965

Published: Feb. 26, 2024

Language: Английский

Citations

0
Palladium-Catalyzed N-Alkenylation of N-Aryl Phosphoramidates with Alkenes DOI Creative Commons
Li Yuan, Ge Wu, Jia Li

et al.

Molecules, Journal Year: 2023, Volume and Issue: 28(11), P. 4466 - 4466

Published: May 31, 2023

Versatile and concise Pd-catalyzed oxidative N-alkenylation of N-aryl phosphoramidates with alkenes is described in this study, a reaction that great significance but surprisingly unexploited. The transformation proceeds under mild conditions, using O2 as green oxidant TBAB an effective additive. An efficient catalytic system allows variety drug-related substrates to participate these transformations, which interest the drug discovery development phosphoramidates.

Language: Английский

Citations

1
Cu(Ii)-Catalyzed Efficient Construction of 1,3-Naphthoxazines from 2-Naphthols, Amidines and N, N-Dimethylethanolamine DOI
Jinqiang Kuang,

Meiqi Geng,

Maozhong Miao

et al.

Published: Jan. 1, 2023

Herein, we report a Cu(II)-catalyzed multi-component reaction for the facile synthesis of 1,3-naphthoxazines from amidines and ortho-quinone methides, which are in situ-generated 2-naphthols N, N-dimethylaminoethanol (DMEA). DMEA acts as unique efficient C1 synthon well solvent. A variety with diverse functional groups were provided moderate to excellent yields.

Language: Английский

Citations

0