European Journal of Organic Chemistry,
Journal Year:
2023,
Volume and Issue:
27(4)
Published: Nov. 22, 2023
Abstract
A
novel
method
has
been
developed
for
the
synthesis
of
fused
dihydroisoquinoline
frameworks
through
a
Rh(III)‐catalyzed
annulation
3‐aryl‐2
H
‐benzo[
e
][1,2,4]thiadiazine‐1,1‐dioxides
with
vinylene
carbonates
by
C−H
bond
activation.
This
is
first
report
on
oxidative
functionalization
aryl‐2
][1,2,4]thiadiazine‐1,1‐dioxide
carbonate
to
afford
angularly
heterocycles
in
good
yields
high
functional
group
tolerance.
In
this
approach,
acts
as
glycolaldehyde
surrogate
construct
ring
systems.
Chemical Communications,
Journal Year:
2024,
Volume and Issue:
60(26), P. 3571 - 3574
Published: Jan. 1, 2024
Herein,
a
novel
Pd-catalyzed
denitrogenation/vinylation
of
benzotriazinones
using
vinylene
carbonate
as
the
vinylation
reagent
is
reported.
This
transformation
demonstrates
an
unprecedented
skeletal
editing
approach,
effectively
converting
NN
to
CC
fragments
European Journal of Organic Chemistry,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Feb. 21, 2025
Abstract
Nitrogen‐containing
heterocyclic
compounds
are
the
core
skeletons
of
many
natural
products,
bioactive
molecules
and
drugs,
transition
metal‐catalyzed
hydrazine‐directed
C−H
bond
activation/annulation
reactions
is
one
effective
methods
for
synthesis
nitrogen‐containing
compounds.
In
this
review,
important
research
progress
activation
reviewed
according
to
size
constructed
heterocycles,
substrate
scope
reaction
mechanism
discussed
in
detail,
limitations
future
development
prospects
summarized
outlooked.
The Journal of Organic Chemistry,
Journal Year:
2025,
Volume and Issue:
unknown
Published: April 3, 2025
A
divergent
[5
+
1]
cyclization
reaction
of
o-aminobenzamides
with
vinylene
carbonate
has
been
developed,
rapidly
generating
three
types
cyclic
molecules
including
quinazolinones,
2-methylquinazolinones,
and
2,3-dihydroquinazolinones
high
chemoselectivity.
In
this
discovery,
blooms
as
a
multifunctional
reagent
to
participate
in
cyclization.
The
potential
new
finding
is
further
emphasized
by
assembling
the
benzothiazole
heteroarene
via
[4
version
tolerating
bioactive
units
well.
The Journal of Organic Chemistry,
Journal Year:
2024,
Volume and Issue:
89(5), P. 3238 - 3250
Published: Feb. 14, 2024
A
Co(III)-catalyzed
vinylene
transfer
reaction
enabled
by
carboxylic
acid
is
presented.
This
redox-neutral
transformation
tolerates
various
functional
groups,
including
free
hydroxyl
and
features
practicality.
Five-step
routes
based
on
the
Heck
annulation
have
been
devised
to
total
synthesis
of
8-oxodehydrodiscretamine
2-demethyl-oxypalmatine
without
protection
functionality.
RSC Advances,
Journal Year:
2024,
Volume and Issue:
14(7), P. 4804 - 4809
Published: Jan. 1, 2024
The
step-economical
synthesis
of
C2,
C3-unsubstituted
1-aminoindole
derivatives
through
rhodium-catalyzed
annulation
hydrazines
with
vinylene
carbonate.
The Journal of Organic Chemistry,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Sept. 19, 2024
Transition
metal-catalyzed
C-H
annulation
reactions
have
been
extensively
utilized
for
the
synthesis
of
cinnolines,
especially
N-protected
ones;
however,
none
them
can
yield
cinnolin-4(1
Organic Chemistry Frontiers,
Journal Year:
2024,
Volume and Issue:
11(16), P. 4464 - 4469
Published: Jan. 1, 2024
A
visible-light-induced
oxytrifluoromethylation
reaction
of
carbamate-containing
alkenes
has
been
reported
for
the
synthesis
diverse
cyclic
carbonates
and
vicinal
diols
bearing
trifluoroethyl
substituted
quaternary
centers.
Organic Chemistry Frontiers,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Nov. 12, 2024
We
developed
a
cascade
C–H
activation/[3
+
2]
annulation
for
enaminones
and
vinylene
carbonate,
employing
the
catalyst
[Cp*RhCl
2
]
oxidants.
This
reaction
allows
efficient
synthesis
of
3-carbonylpyrroles.
