Orbital - The Electronic Journal of Chemistry,
Journal Year:
2024,
Volume and Issue:
unknown, P. 26 - 29
Published: May 2, 2024
For
the
first
time,
possibility
of
flavocillin
electrochemical
determination,
assisted
by
vanadium
(III)
oxyhydroxide
has
been
evaluated.
The
determination
will
be
given
gradual
reduction
both
flavonyl
and
penicyllyl
moieties
in
mildly
acidic
medium,
close
to
neutral.
analysis
mathematical
model,
correspondent
reaction
mechanism,
confirms
efficiency
cathodic
process
for
determination.
RSC Advances,
Journal Year:
2023,
Volume and Issue:
13(49), P. 34562 - 34575
Published: Jan. 1, 2023
Metal-organic
frameworks
(MOFs)
and
MXenes
have
demonstrated
immense
potential
for
biomedical
applications,
offering
a
plethora
of
advantages.
MXenes,
in
particular,
exhibit
robust
mechanical
strength,
hydrophilicity,
large
surface
areas,
significant
light
absorption
potential,
tunable
terminations,
among
other
remarkable
characteristics.
Meanwhile,
MOFs
possess
high
porosity
area,
making
them
ideal
protecting
active
biomolecules
serving
as
carriers
drug
delivery,
hence
their
extensive
study
the
field
biomedicine.
However,
akin
to
(nano)materials,
concerns
regarding
environmental
implications
persist.
The
number
studies
investigating
toxicity
biocompatibility
is
growing,
albeit
further
systematic
research
needed
thoroughly
understand
biosafety
issues
biological
effects
prior
clinical
trials.
synthesis
often
involves
use
strong
acids
temperatures,
which,
if
not
properly
managed,
can
adverse
on
environment.
Efforts
should
be
made
minimize
release
harmful
byproducts
ensure
proper
waste
management
during
production
process.
In
addition,
it
crucial
assess
into
environment
applications.
For
applications
MOFs,
several
challenges
exist.
These
include
fabrication
costs,
poor
selectivity,
low
capacity,
quest
stable
water-resistant
well
difficulties
recycling/regeneration
maintaining
chemical/thermal/mechanical
stability.
Thus,
careful
consideration
associated
with
utilization
vital.
addition
manufacturing
processes,
ultimate
fate
must
taken
account.
While
numerous
reviews
been
published
this
perspective
aims
shed
key
issues,
urging
researchers
conduct
field.
aspects
biomedicine
are
discussed,
focusing
main
outlining
future
directions.
Infection and Drug Resistance,
Journal Year:
2025,
Volume and Issue:
Volume 18, P. 1007 - 1033
Published: Feb. 1, 2025
The
increasing
incidence
of
antibiotic
resistance
in
Staphylococcus
aureus
(S.
aureus)
poses
a
substantial
threat
to
global
public
health.
In
recent
decades,
the
evolution
bacteria
and
misuse
antibiotics
have
led
progressive
development
drug
S.
aureus,
resulting
worldwide
rise
methicillin-resistant
(MRSA)
infection
rates.
Understanding
molecular
mechanisms
underlying
staphylococcal
resistance,
treatments
for
infections,
efficacy
nanomaterials
addressing
multi-drug
is
crucial.
This
review
explores
mechanisms,
which
include
limiting
uptake,
target
modification,
inactivation
through
production
degrading
enzymes,
active
efflux
drugs.
It
also
examines
current
therapeutic
strategies,
such
as
combination
therapy,
phage
monoclonal
antibody
nanoparticle
with
particular
emphasis
on
role
silver-based
nanomaterials.
Nanoparticles
possess
ability
overcome
offering
novel
avenue
management
drug-resistant
bacteria.
demonstrated
potent
antibacterial
activity
against
various
including
cell
membrane
disruption,
generation
reactive
oxygen
species
(ROS),
inhibition
essential
cellular
processes.
highlights
need
further
research
optimize
design,
enhance
their
potency,
ensure
biocompatibility
biodegradability.
ultimately
concludes
by
emphasizing
importance
multifaceted
approach
treatment,
new
antibiotics,
investment
stewardship
programs
prevent
misuse,
exploration
natural
compounds
bacteriocins
potential
antimicrobial
agents.
Nanoscale Advances,
Journal Year:
2024,
Volume and Issue:
6(14), P. 3513 - 3532
Published: Jan. 1, 2024
Recent
advancements
in
MXene-based
wound
dressings
are
discussed,
focusing
on
their
contributions
to
tissue
regeneration,
infection
control,
anti-inflammation
and
photothermal
effects,
targeted
therapeutic
delivery.
