Ultrasonics Sonochemistry,
Journal Year:
2023,
Volume and Issue:
102, P. 106741 - 106741
Published: Dec. 23, 2023
Ultrasonic
irradiation
serves
as
a
vigorous
and
environmentally
sustainable
approach
for
augmenting
multicomponent
reactions
(MCRs),
offering
benefits
such
thermal
enhancement,
agitation,
activation,
among
others.
Malononitrile
emerges
versatile
reagent
in
this
context,
participating
myriad
of
MCRs
to
produce
structurally
diverse
heterocyclic
frameworks.
This
review
encapsulates
the
critical
role
malononitrile
sonochemical
synthesis
these
structures.
The
paper
further
delves
into
biochemical
pharmacological
implications
heterocycles,
elucidating
their
reaction
mechanisms
well
delineating
method's
scope
limitations.
We
furnish
an
overview
merits
challenges
inherent
synthetic
offer
insights
potential
avenues
future
research.
ChemistrySelect,
Journal Year:
2025,
Volume and Issue:
10(1)
Published: Jan. 1, 2025
Abstract
1,4‐Naphthoquinones
(1,4‐NQs)
are
an
important
class
of
molecules
with
diverse
pharmaceutical
applications.
Lawsone,
a
naturally
occurring
molecule
range
bioactivities,
falls
in
the
1,4‐NQs.
It
possesses
1,3‐dicarbonyl
functionality,
which
has
been
utilized
synthesis
bis‐lawsones
reaction
aldehydes.
In
this
review
we
have
discussed
notable
developments
bis‐lawsone
from
2009
to
2023.
Also,
highlights
limitations
and
future
perspectives
area.
RSC Advances,
Journal Year:
2023,
Volume and Issue:
13(47), P. 32858 - 32892
Published: Jan. 1, 2023
This
review
highlights
recent
developments
in
the
microwave-assisted
organic
synthesis
of
N-
and
O-containing
heterocycles
with
specific
examples
pyrazolopyrimidines-,
coumarin-,
quinoline-,
isatin-based
scaffolds
their
associated
biological
activities.
Synthesis,
Journal Year:
2024,
Volume and Issue:
56(16), P. 2445 - 2461
Published: Jan. 8, 2024
Abstract
The
unique
reactivity
and
beneficial
features
of
the
5-aminotetrazole
synthon
(1H-tetrazol-5-amine)
have
made
it
a
versatile
effective
building
block
in
synthesis
heterocyclic
compounds.
In
addition,
several
drugs
containing
this
scaffold
with
wide
array
biological
properties
been
already
introduced.
Heterocyclic
structures
are
backbone
many
biologically
active
industrially
important
5-Aminotetrazole
is
one
favored
synthons
used
preparation
heterocycle-bearing
compounds,
especially
multicomponent
synthesis.
This
review
highlights
comprehensive
overview
emerging
applications
as
key
component
frameworks
through
reactions,
reported
between
2017
July
2023.
1
Introduction
2
3
Tetrazolopyrimidine
Compounds
4
Spiro
5
Miscellaneous
6
Conclusion
BMC Chemistry,
Journal Year:
2025,
Volume and Issue:
19(1)
Published: March 15, 2025
N-aryl
amides
hold
significant
importance
in
organic
chemistry
due
to
their
widespread
presence
pharmaceuticals,
agrochemicals,
and
various
bioactive
compounds.
As
a
result,
catalysts
preparation
methodologies
for
amide
derivatives
have
long
been
target
of
active
investigation
interest.
In
the
current
work,
simple
accessible
route
was
adopted
magnetic
catalyst
[Fe3O4@SiO2-DHB/DI(S-NH)-Pd
(0)]
then
its
catalysis
three-component
synthesis
via
carbonylation
reaction
between
aryl
iodides
amines
examined.
experiments,
efficiency
producing
range
with
high
yields
short
under
mild
conditions
unequivocally
confirmed,
confirmed
through
experiments.
High
desired
compound
ease
separation,
reusability
catalysts,
conditions,
accommodation
substrates,
thorough
analysis
determination
produced
compounds
characterization
purification
taken
as
key
features
this
work.
